Gene: Rnf112

Name
ring finger protein 112
MGI ID
MGI:106611
Synonyms
neurolastin Zfp179 bfp
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (289) Expression & images (74) Disease models (0) Order (3)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Bulging eye HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / RR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.292 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Iris/Pupil HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Mean cell hemoglobin concentration HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Mean cell hemoglobin concentration HOM 2f:4m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_007_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal deposits HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Open Field / Percentage center time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.520 Success
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Eosinophil differential count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Mean platelet volume HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 3f:0m 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 0f:2m 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Body length HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.483 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Urinalysis / Magnesium HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.841 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Lens Opacity HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Open Field / Periphery distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00657 Success
Rnf112tm1.1(KOMP)Vlcg JAX Light-Dark Test / Dark side time spent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.644 Success
Rnf112tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep light phase percent HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.608 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Retina (combined) HOM 8f:7m Not processed Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Hematocrit HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Hematocrit HOM 2f:4m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_004_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 7f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_011_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.945 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Rotarod / Learning slope HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0110 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Dilation HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.299 Success
Rnf112tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Fat mass HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.608 Success
Rnf112tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 0f:2m 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 3f:0m 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tremor HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Viability Primary Screen / Outcome HOM 67f:69m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Large Unstained Cell (LUC) count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Lymphocyte cell count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Sleep Wake / Light sleep bout lengths mean HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.424 Success
Rnf112tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / ST HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.947 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Open Field / Center distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.106 Success
Rnf112tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 3f:0m 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 0f:2m 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Light-Dark Test / Percent time in dark HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.495 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal vascularization HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Retinal Blood Vessels Pattern HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.783 Success
Rnf112tm1.1(KOMP)Vlcg JAX Sleep Wake / Light sleep bout lengths standard deviation HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0781 Success
Rnf112tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / PQ HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.577 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Platelet count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Platelet count HOM 2f:4m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Position HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.873 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Eyelid closure HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Light-Dark Test / Time mobile light side HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00337 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Sleep Wake / Breath rate during sleep standard deviation HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.621 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Iris transilumination HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Eosinophil cell count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Urinalysis / Albumin to Creatinine ratio HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.143 Success
Rnf112tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 7f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_009_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Hemoglobin HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Hemoglobin HOM 2f:4m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_003_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rnf112tm1.1(KOMP)Vlcg JAX Open Field / Whole arena resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00514 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Vitreous HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Lens HOM 8f:7m Fisher Exact Test framework 0.122 Success
Rnf112tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / QTc HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.294 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Head size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb grip strength normalised against body weight HOM 7f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_010_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Optic Disc HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Open Field / Center average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.156 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Narrow eye opening HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep dark phase percent HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.121 Success
Rnf112tm1.1(KOMP)Vlcg JAX Heart Weight / Heart weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.445 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.969 Success
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Neutrophil differential count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Persistence of hyaloid vascular system HOM 8f:7m Fisher Exact Test framework 0.0200 Success
Rnf112tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0224 Success
Rnf112tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.582 Success
Rnf112tm1.1(KOMP)Vlcg JAX Light-Dark Test / Latency to first transition into dark HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.837 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Shape HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Open Field / Periphery average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00860 Success
Rnf112tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / QTc Dispersion HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0617 Success
Rnf112tm1.1(KOMP)Vlcg JAX Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Eye HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Sleep Wake / Dark sleep bout lengths standard deviation HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.635 Success
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Lymphocyte differential count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Monocyte differential count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Light-Dark Test / Percent time in light HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.495 Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.183 Success
Rnf112tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / rMSSD HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.877 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Open Field / Distance travelled - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00529 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Snout size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / PR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.813 Success
Rnf112tm1.1(KOMP)Vlcg JAX Sleep Wake / Dark sleep bout lengths mean HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.854 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Synechia HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 3f:0m 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 0f:2m 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Light-Dark Test / Light side time spent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.644 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Open Field / Periphery permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.521 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / HR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.511 Success
Rnf112tm1.1(KOMP)Vlcg JAX Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.721 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Aggression HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Startle response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb grip strength measurement mean HOM 7f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_GRS_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Eyelid morphology HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Mean cell volume HOM 2f:4m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_005_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Mean cell volume HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep daily percent HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.547 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Cornea HOM 8f:7m Fisher Exact Test framework 0.0264 Success
Rnf112tm1.1(KOMP)Vlcg JAX Open Field / Center permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.520 Success
Rnf112tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 0f:2m 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 3f:0m 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Basophil cell count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.113 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0980 Success
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Red blood cell count HOM 2f:4m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_002_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Red blood cell count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Urinalysis / Creatinine HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.391 Success
Rnf112tm1.1(KOMP)Vlcg JAX Light-Dark Test / Fecal boli HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.637 Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Iris Pigmentation HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Sleep Wake / Breath rate during sleep mean HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00700 Success
Rnf112tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / HRV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.758 Success
Rnf112tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0943 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Retinal Blood Vessels HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep bout lengths mean HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.947 Success
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Neutrophil cell count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Rotarod / Average duration HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.464 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Urinalysis / Glucose HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.866 Success
Rnf112tm1.1(KOMP)Vlcg JAX Light-Dark Test / Side changes HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000986 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal Sclerization HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Hole-board Exploration / Total holepokes HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0457 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Eye Hemorrhage or Blood Presence HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Monocyte cell count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Open Field / Number of rears - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0283 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Bone Area HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.589 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Fusion between cornea and lens HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Mean corpuscular hemoglobin HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Mean corpuscular hemoglobin HOM 2f:4m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_006_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0278 Success
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Large Unstained Cell (LUC) differential count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / CV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.845 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.749 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Basophil differential count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Sleep Wake / Peak wake with respect to dark onset median HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.859 Success
Rnf112tm1.1(KOMP)Vlcg JAX Light-Dark Test / Time mobile dark side HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000535 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Retinal Blood Vessels Structure HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Urinalysis / microAlbumin (calculated) HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.718 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Gait HOM 8f:8m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / QRS HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.177 Success
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / Red blood cell distribution width HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Ears HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Rotarod / Learning difference HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00574 Success
Rnf112tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Lean mass HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.367 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Light Response HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Open Field / Whole arena average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00523 Success
Rnf112tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal opacity HOM 8f:7m Fisher Exact Test framework 1.00 Success
Rnf112tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep bout lengths standard deviation HOM 4f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0624 Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Rnf112tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / White blood cell count HOM 2f:4m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_HEM_001_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Rnf112tm1.1(KOMP)Vlcg JAX Hematology / White blood cell count HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No N/A
Bone marrow 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No  (2/2) N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132)  (1/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No  (2/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (2/3) N/A
Dorsal root ganglion 2  (1/47)  (2/3) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/3)  Wholemount images
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485) N/A
Fronto-nasal process 2  (1/48) Image Only N/A
Hand 2  (1/485) N/A
Head 2  (5/485)  (2/3) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485)  (2/3) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) Image Only N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485)  (2/3) N/A
Nose 2  (1/51) N/A
Oral cavity 2  (1/485) Image Only N/A
Skin 2  (1/485) Image Only N/A
Spinal cord 2  (1/50)  (2/3) N/A
Tail 2  (1/485)  (2/3) N/A
Tail somite 2  (1/485) Image Only N/A

 Associated Images

Sleep Wake: Wake state (bmp file)
7 Images
X-ray: XRay Images Dorso Ventral
9 Images
Embryo LacZ: LacZ images wholemount
12 Images
X-ray: XRay Images Lateral Orientation
9 Images
X-ray: XRay Images Forepaw
9 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Rnf112tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Rnf112tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Rnf112tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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