Larp4b | La ribonucleoprotein 4B

GeneMGI:106330Synonyms: Larp5, D13Wsu64e, +1 more

Physiological systems

15 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system

13 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased mean platelet volume1 supporting datasetLarp4bem1(IMPC)WtsihomozygoteEarly adult3.86x10-9 
decreased hemoglobin content1 supporting datasetLarp4bem1(IMPC)WtsihomozygoteEarly adult1.15x10-6 
increased circulating insulin level1 supporting datasetLarp4bem1(IMPC)WtsihomozygoteEarly adult3.83x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Larp4bem1(IMPC)WtsiDeletionmouse
Larp4btm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Larp4btm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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