Gene: Hells

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Name
helicase, lymphoid specific
MGI ID
MGI:106209
Synonyms
Lysh LSH PASG proliferation-associated SNF2-like YFK8 E130115I21Rik
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased monocyte cell number Hellstm1a(EUCOMM)Wtsi HOM Early adult 9.71×10-07
preweaning lethality, complete penetrance Hellstm1b(EUCOMM)Wtsi HOM   Early adult 7.54×10-06
decreased circulating triglyceride level Hellstm1a(EUCOMM)Wtsi HOM Early adult 5.80×10-14
decreased circulating cholesterol level Hellstm1a(EUCOMM)Wtsi HOM Early adult 7.05×10-06
abnormal gait Hellstm1a(EUCOMM)Wtsi HOM Early adult 5.85×10-07
hyperactivity Hellstm1b(EUCOMM)Wtsi HET Early adult 1.24×10-05
decreased circulating LDL cholesterol level Hellstm1a(EUCOMM)Wtsi HOM Early adult 5.59×10-05
decreased granulocyte number Hellstm1a(EUCOMM)Wtsi HOM Early adult 1.12×10-06
decreased IgG1 level Hellstm1a(EUCOMM)Wtsi HOM Early adult 1.38×10-06

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590) N/A
Blood 2 No N/A
Bone 2 No N/A
Bone marrow 2 No N/A
Brain 2 No  (3/590) N/A
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/377)  (2/2)  Wholemount images
Cerebellum 2 No  (3/590) N/A
Cerebral cortex 2 No  (2/590) N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2)  Wholemount images
Cranium 2 No N/A
Diaphragm 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Harderian gland 2 No N/A
Heart 2 No  (1/590) N/A
Hindlimb 2 No N/A
Hippocampus 2 No  (3/590) N/A
Hypothalamus 2 No  (2/590) N/A
Kidney 2 No  (20/590) N/A
Large intestine 2 No  (10/590) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Main olfactory bulb 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No  (2/590) N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/590)  (1/2)  Wholemount images
Oviduct 2 No N/A
Pancreas 2 No  (5/590) N/A
Parathyroid gland 2 No N/A
Parotid gland 2 No N/A
Penis 2 No N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590) N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/590)  (1/2)  Wholemount images
Spinal cord 2 No  (2/590) N/A
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590)  (2/2)  Wholemount images
Stomach pyloric region 2 No N/A
Striatum 2 No  (3/590) N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (5/590)  (1/2)  Wholemount images
Thymus 2 No  (2/2)  Wholemount images
Thyroid gland 2 No  (16/590) N/A
Tongue 2 No  (5/127) N/A
Trachea 2 No  (2/590) N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No  (1/2)  Wholemount images
Vagina 2 No N/A
Vas deferens 2 No  (15/388) N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Adult LacZ: LacZ Images Wholemount
12 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Hellstm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Hellstm44592(L1L2_gt0) Targeting vectors
Hellstm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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