Gene: Cyp7a1

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Name
cytochrome P450, family 7, subfamily a, polypeptide 1
MGI ID
MGI:106091
Synonyms
cholesterol 7 alpha hydroxylase
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased leukocyte cell number Cyp7a1tm1b(EUCOMM)Wtsi HOM Early adult 8.53×10-08
increased startle reflex Cyp7a1tm1b(EUCOMM)Wtsi HOM Early adult 2.01×10-07
abnormal lens morphology Cyp7a1tm1b(EUCOMM)Wtsi HOM Early adult 7.54×10-07
increased circulating bilirubin level Cyp7a1tm1b(EUCOMM)Wtsi HOM Early adult 2.91×10-06
decreased blood urea nitrogen level Cyp7a1tm1b(EUCOMM)Wtsi HOM Early adult 1.22×10-06
abnormal retinal vasculature morphology Cyp7a1tm1b(EUCOMM)Wtsi HOM Early adult 1.88×10-05
increased circulating alkaline phosphatase level Cyp7a1tm1b(EUCOMM)Wtsi HOM Early adult 4.29×10-17
increased circulating cholesterol level Cyp7a1tm1b(EUCOMM)Wtsi HOM Early adult 2.74×10-08
increased circulating amylase level Cyp7a1tm1b(EUCOMM)Wtsi HOM Early adult 2.80×10-05
cataract Cyp7a1tm1b(EUCOMM)Wtsi HOM Early adult 5.51×10-07
increased circulating unsaturated transferrin level Cyp7a1tm1b(EUCOMM)Wtsi HOM Early adult 1.35×10-06
increased circulating HDL cholesterol level Cyp7a1tm1b(EUCOMM)Wtsi HOM Early adult 1.14×10-13

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Cyp7a1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Cyp7a1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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