Cbx1 - chromobox 1 | International Mouse Phenotyping Consortium

Genes Phenotypes

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Gene: Cbx1

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Name

chromobox 1

MGI ID

MGI:105369

Synonyms

MOD1 Cbx-rs2 Hp1beta M31 HP1B E430007M08Rik

Viability

Homozygous - Lethal

Embryo viewer

N/A

Phenotype	System	Allele	Zyg	Sex	Life Stage	P Value
preweaning lethality, complete penetrance		Cbx1^{tm1a(EUCOMM)Wtsi}	HOM		Early adult	0.00

Expression

Table Images

Expression No Expression Ambiguous No Tissue Available

Anatomy	#HET Specimens	HOM Images?	WT Expr	Mutant Expr	Images
Adrenal gland	2	No	(2/584)	(2/2)	N/A
Aorta	2	No			N/A
Blood vessel	2	No		(2/2)	N/A
Bone	2	No			N/A
Brain	2	No		(2/2)	N/A
Brainstem	2	No			N/A
Brown adipose tissue	2	No			N/A
Cartilage tissue	2	No		(2/2)	N/A
Cerebellum	2	No			N/A
Cerebral cortex	2	No			N/A
Eye	2	No			N/A
Gall bladder	2	No		(1/2)	N/A
Heart	2	No		(2/2)	N/A
Hippocampus	2	No			N/A
Hypothalamus	2	No			N/A
Kidney	2	No	(18/584)	(2/2)	N/A
Large intestine	2	No	(10/584)	(2/2)	N/A
Liver	2	No		(2/2)	N/A
Lower urinary tract	2	No		(2/2)	N/A
Lung	2	No		(2/2)	N/A
Lymph node	2	No		(2/2)	N/A
Mammary gland	2	No			N/A
Esophagus	2	No		(2/2)	N/A
Olfactory lobe	2	No			N/A
Ovary	2	No	(1/584)	(1/2)	N/A
Oviduct	2	No		(1/2)	N/A
Pancreas	2	No	(5/584)	(2/2)	N/A
Parathyroid gland	2	No			N/A
Peripheral nervous system	2	No		(2/2)	N/A
Peyer's patch	2	No		(2/2)	N/A
Pituitary gland	2	No		(1/2)	N/A
Prostate gland	2	No	(12/584)		N/A
Skeletal muscle tissue	2	No		(2/2)	N/A
Skin	2	No		(2/2)	N/A
Small intestine	2	No	(9/584)	(2/2)	N/A
Spinal cord	2	No		(2/2)	N/A
Spleen	2	No	(2/584)	(2/2)	N/A
Stomach	2	No	(12/584)	(2/2)	N/A
Striatum	2	No			N/A
Testis	2	No	(2/584)	(1/2)	N/A
Thymus	2	No		(2/2)	N/A
Thyroid gland	2	No	(15/584)	(1/2)	N/A
Trachea	2	No		(2/2)	N/A
Uterus	2	No		(1/2)	N/A
White adipose tissue	2	No			N/A

LacZ Wholemount Images

LacZ Section Images

Cbx1^{tm1a(EUCOMM)Wtsi}
lower urinary tract, HET, Male, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
testis, HET, Male, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
lymph node, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
peyer's patch, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
pituitary gland, peripheral nervous system, HET, Female, WTSI

View all 27 images

Cbx1^{tm1a(EUCOMM)Wtsi}
testis, HET, Male, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
peyer's patch, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
ovary, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
thyroid gland, trachea, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
heart, HET, Female, WTSI

View all 16 images

Cbx1^{tm1a(EUCOMM)Wtsi}
peyer's patch, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
gall bladder, liver, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
oesophagus, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
large intestine, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
lymph node, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
peyer's patch, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
thymus, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
spleen, HET, Male, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
pituitary gland, peripheral nervous system, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
brain, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
spinal cord, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
inguinal fat pad, mammary gland, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
pinna, skin, HET, Male, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
skin, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
lower urinary tract, HET, Male, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
kidney, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
urinary bladder, lower urinary tract, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
thyroid gland, trachea, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
adrenal gland, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
skeletal muscle tissue, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
testis, HET, Male, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
ovary, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
thyroid gland, trachea, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
lung, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
inguinal fat pad, mammary gland, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
heart, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
inguinal fat pad, mammary gland, HET, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
pinna, skin, HET, Male, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
inguinal fat pad, mammary gland, HET, Female, WTSI

No Embryo expression data was found for this gene.

Associated Images

Legacy Phenotype Associated Images

Cbx1^{tm1a(EUCOMM)Wtsi}
body, WT, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
head, WT, Female, WTSI

Cbx1^{tm1a(EUCOMM)Wtsi}
body, WT, Female, WTSI

View all 143 images

Cbx1^{tm1a(EUCOMM)Wtsi}
back skin, HET, Female, WTSI

Disease Models

By Annotation and Orthology (0)
By phenotypic Similarity (0)

No associations by disease annotation and gene orthology found.

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MGI Allele	Allele Type	Produced
Cbx1^{tm1a(EUCOMM)Wtsi}	KO first allele (reporter-tagged insertion with conditional potential)	Mice, Targeting vectors, ES Cells
Cbx1^{tm1(KOMP)Vlcg}	Reporter-tagged deletion allele (with selection cassette)	Targeting vectors, ES Cells

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Gene: Cbx1

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Expression

IMPC lacZ Expression Data

LacZ Wholemount Images

LacZ Section Images

LacZ Section Images

Associated Images

Legacy Phenotype Associated Images

Disease Models

Order Mouse and ES Cells

This service may be affected by the Covid-19 pandemic. See how

The IMPC Newsletter

Access Data Release 10.1 Data