Gene: Cxcr2

Name
chemokine (C-X-C motif) receptor 2
MGI ID
MGI:105303
Synonyms
Gpcr16 Cmkar2 IL8RA Il8rb IL-8Rh IL-8rb CD128
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased granulocyte number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased mature B cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased gamma-delta T cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased CD103-positive CD11b-low dendritic cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased effector memory CD4-positive, alpha-beta T cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased memory-marker CD4-positive NK T cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased circulating calcium level Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 4.95×10-07
decreased circulating thyroxine level Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 7.58×10-05
increased Ly6C high monocyte number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased CD8-positive, alpha-beta T cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased effector memory CD8-positive, alpha-beta T cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased pre-pro B cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased circulating magnesium level Cxcr2tm1a(EUCOMM)Wtsi HET postnatal 2.15×10-05
increased memory-marker NK cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased neutrophil cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 1.00×10-07
decreased B cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased circulating total protein level Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 4.43×10-05
increased eosinophil cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased memory-marker gamma-delta T cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased monocyte cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased effector memory T-helper cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased circulating creatinine level Cxcr2tm1a(EUCOMM)Wtsi HET postnatal 1.93×10-06
decreased immature B cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased T cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased KLRG1+ CD8 alpha beta T cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
increased Ly6C low monocyte number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00
decreased pre-B cell number Cxcr2tm1a(EUCOMM)Wtsi HOM postnatal 0.00

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

Expression data not available

 Associated Images

Spleen Immunophenotyping: Images associated with FACS analysis
72 Images
X-ray: XRay Images Forepaw
26 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
25 Images
X-ray: XRay Images Dorso Ventral
76 Images
X-ray: XRay Images Lateral Orientation
50 Images
X-ray: XRay Images Skull Lateral Orientation
25 Images
Anti-nuclear antibody assay
17 Images
DSS Histology
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Cxcr2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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