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Gene: Dusp1

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Name
dual specificity phosphatase 1
MGI ID
MGI:105120
Synonyms
erp mkp-1 3CH134 Ptpn16 MKP1
Viability
No data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (3) Measurements chart (131) All data table (235)
Expression & images (45) Disease models (0) Order (1)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased body weight Dusp1tm1(KOMP)Wtsi HOM   Early adult 1.56×10-07
increased circulating magnesium level Dusp1tm1(KOMP)Wtsi HOM   Early adult 6.73×10-05
decreased circulating alanine transaminase level Dusp1tm1(KOMP)Wtsi HOM Early adult 1.19×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590) N/A
Blood vessel 2 No  (2/2) N/A
Bone 2 No N/A
Brain 2 No  (3/590)  (2/2) N/A
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/590) N/A
Cerebral cortex 2 No  (2/590) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/590) N/A
Hippocampus 2 No  (3/590) N/A
Hypothalamus 2 No  (2/590) N/A
Kidney 2 No  (20/590)  (2/2) N/A
Large intestine 2 No  (10/590) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/590)  (2/2) N/A
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Esophagus 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/590) N/A
Ovary 2 No  (1/590)  (1/2) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/590) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590) N/A
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590)  (2/2) N/A
Striatum 2 No  (3/590) N/A
Testis 2 No  (5/590)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (16/590) N/A
Trachea 2 No  (2/590)  (2/2) N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Dusp1tm1(KOMP)Wtsi
brain, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
kidney, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
urinary bladder, lower urinary tract, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
tail, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
trachea, thyroid gland, HET, Female, WTSI

View all 11 images

Dusp1tm1(KOMP)Wtsi
kidney, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
urinary bladder, lower urinary tract, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
trachea, thyroid gland, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
ovary, oviduct, uterus, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
stomach, oesophagus, HET, Female, WTSI

View all 6 images

Dusp1tm1(KOMP)Wtsi
pinna, skin, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
skin, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
ovary, oviduct, uterus, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
testis, HET, Male, WTSI
Dusp1tm1(KOMP)Wtsi
kidney, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
urinary bladder, lower urinary tract, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
blood vessel, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
stomach, oesophagus, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
trachea, thyroid gland, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
brain, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
trachea, thyroid gland, HET, Female, WTSI
Dusp1tm1(KOMP)Wtsi
pinna, skin, HET, Female, WTSI
No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images
Dusp1tm1(KOMP)Wtsi
forearm, WT, Male, WTSI
Dusp1tm1(KOMP)Wtsi
body, WT, Male, WTSI
Dusp1tm1(KOMP)Wtsi
head, WT, Female, WTSI
Dusp1tm1(KOMP)Wtsi
forearm, WT, Female, WTSI
Dusp1tm1(KOMP)Wtsi
body, WT, Male, WTSI

View all 128 images

Dusp1tm1(KOMP)Wtsi
back skin, WT, Female, WTSI
Dusp1tm1(KOMP)Wtsi
back skin, HOM, Female, WTSI
Dusp1tm1(KOMP)Wtsi
back skin, WT, Female, WTSI
Dusp1tm1(KOMP)Wtsi
abnormal epidermal pigmentation, HOM, Female, WTSI

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Dusp1tm1(KOMP)Wtsi Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells

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