Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased startle reflex Nintm1b(EUCOMM)Hmgu HOM Early adult 0.00
hyperactivity Nintm1b(EUCOMM)Hmgu HOM   Early adult 3.94×10-06
improved glucose tolerance Nintm1b(EUCOMM)Hmgu HOM Early adult 7.02×10-05
abnormal auditory brainstem response Nintm1b(EUCOMM)Hmgu HOM   Early adult 1.48×10-06
decreased anxiety-related response Nintm1b(EUCOMM)Hmgu HOM   Early adult 1.21×10-05
increased exploration in new environment Nintm1b(EUCOMM)Hmgu HOM Early adult 4.38×10-13
increased mean corpuscular hemoglobin Nintm1b(EUCOMM)Hmgu HOM Early adult 6.81×10-05
decreased prepulse inhibition Nintm1b(EUCOMM)Hmgu HOM Early adult 6.93×10-18
cardiovascular system phenotype Nintm1b(EUCOMM)Hmgu HOM Early adult 4.11×10-07
increased circulating LDL cholesterol level Nintm1b(EUCOMM)Hmgu HOM Early adult 4.44×10-06

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
4 Yes  (4/583)  Wholemount images
4 Yes  (1/583)  (2/6)  Wholemount images
4 Yes  (2/6)  Wholemount images
4 Yes  (4/583)  (6/6)  Wholemount images
4 No  (2/583)  (6/6) N/A
4 No N/A
4 No  (1/583)  (2/6) N/A
4 Yes  (12/371)  (6/6)  Wholemount images
4 No  (3/583)  (6/6) N/A
4 No  (2/583)  (6/6) N/A
4 Yes  (6/6)  Wholemount images
4 No  (12/127)  (6/6) N/A
4 No N/A
4 Yes  Wholemount images
4 Yes  (2/127)  (6/6)  Wholemount images
4 Yes  (18/132)  Wholemount images
4 Yes  (7/407)  (2/6)  Wholemount images
4 No N/A
4 Yes  (2/6)  Wholemount images
4 No N/A
4 Yes  Wholemount images
4 Yes  (2/583)  (2/6)  Wholemount images
4 Yes  (2/6)  Wholemount images
4 No  (3/583)  (6/6) N/A
4 No  (2/583)  (6/6) N/A
4 Yes  (14/127)  (6/6)  Wholemount images
4 Yes  (6/127)  (6/6)  Wholemount images
4 Yes  (21/583)  (6/6)  Wholemount images
4 Yes  (10/583)  (6/6)  Wholemount images
4 Yes  Wholemount images
4 No  (1/583)  (5/6) N/A
4 Yes  (2/583)  (6/6)  Wholemount images
4 Yes  (1/583)  Wholemount images
4 Yes  (6/6)  Wholemount images
4 Yes  Wholemount images
4 Yes  Wholemount images
4 Yes  Wholemount images
4 No  (6/6) N/A
4 No  (2/583)  (6/6) N/A
4 No N/A
4 Yes  (1/583)  (2/6)  Wholemount images
4 Yes  (3/6)  Wholemount images
4 No  (5/583) N/A
4 Yes  (1/563)  (5/6)  Wholemount images
4 Yes  Wholemount images
4 Yes  (3/6)  Wholemount images
4 No  (2/583)  (2/6) N/A
4 No N/A
4 Yes  (1/583)  (6/6)  Wholemount images
4 Yes  (12/583)  Wholemount images
4 Yes  Wholemount images
4 Yes  (2/6)  Wholemount images
4 No N/A
4 Yes  (1/583)  (2/6)  Wholemount images
4 No  (9/583)  (6/6) N/A
4 Yes  (3/583)  (6/6)  Wholemount images
4 Yes  (3/583)  Wholemount images
4 Yes  (13/583)  (6/6)  Wholemount images
4 No N/A
4 No  (3/583)  (6/6) N/A
4 Yes  Wholemount images
4 Yes  (2/130)  Wholemount images
4 Yes  (6/583)  (3/6)  Wholemount images
4 No  (6/6) N/A
4 Yes  (1/583)  (2/6)  Wholemount images
4 Yes  (17/583)  Wholemount images
4 Yes  (5/127)  (2/6)  Wholemount images
4 Yes  (3/583)  (6/6)  Wholemount images
4 Yes  (6/6)  Wholemount images
4 Yes  (5/6)  Wholemount images
4 Yes  (3/6)  Wholemount images
4 Yes  (1/6)  Wholemount images
4 No  (15/382) N/A
4 No  (2/6) N/A
4 Yes  Wholemount images
4 Yes  Wholemount images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
9  (6/505)  (11/11) N/A
9  (1/505) N/A
9  (1/506)  (11/11)  Wholemount images
9  (1/505)  (2/11)  Wholemount images
9  (1/505) N/A
9  (1/302)  (9/11) N/A
9  (1/505) N/A
9  (1/505)  (9/11)  Wholemount images
9  (1/505) N/A
9  (5/505)  (11/11)  Wholemount images
9  (1/505)  Wholemount images
9  (6/505)  (11/11) N/A
9  (1/505)  (9/11)  Wholemount images
9  (1/503)  Wholemount images
9  (1/302)  (4/11) N/A
9  (1/503)  Wholemount images
9  (1/505) N/A
9  (1/505) N/A
9  (1/505)  (2/11) N/A
9  (1/503) N/A
9  (1/505) N/A
9  (1/505)  (11/11)  Wholemount images
9  (1/505) N/A
9  (1/302)  (9/11) N/A
9  (1/302)  (9/11) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
223 Images
Adult LacZ: LacZ Images Wholemount
377 Images
Eye Morphology: Images Slit Lamp
2 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Eye Morphology: Images Ophthalmoscopy
1 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Nintm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Nintm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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