Gene: Slc6a5

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Name
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
MGI ID
MGI:105090
Synonyms
Glyt2
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Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic growth retardation Slc6a5tm1.1(KOMP)Vlcg HET embryonic day 9.5 0.00
increased mean corpuscular hemoglobin concentration Slc6a5tm1.1(KOMP)Vlcg HET postnatal 4.97×10-05
abnormal seminal vesicle morphology Slc6a5tm1.1(KOMP)Vlcg HET postnatal 0.00
abnormal embryo size Slc6a5tm1.1(KOMP)Vlcg HET embryonic day 9.5 0.00
preweaning lethality, complete penetrance Slc6a5tm1.1(KOMP)Vlcg HOM n/a 0.00

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 3 No  (2/584)  (2/3) N/A
Aorta 3 No N/A
Blood 3 No N/A
Bone marrow 3 No N/A
Brain 3 No  (1/3) N/A
Brainstem 3 No N/A
Brown adipose tissue 3 No N/A
Cartilage tissue 3 No N/A
Cecum 3 No  (12/383)  (1/3) N/A
Cerebellum 3 No  (2/3) N/A
Cerebral cortex 3 No N/A
Chest bone 3 No N/A
Colon 3 No  (12/127)  (1/3) N/A
Diaphragm 3 No N/A
Duodenum 3 No  (2/127) N/A
Epididymis 3 No  (18/134)  (2/3) N/A
Esophagus 3 No  (7/415)  (1/3) N/A
Eye 3 No N/A
Gall bladder 3 No N/A
Gonadal fat pad 3 No N/A
Harderian gland 3 No N/A
Heart 3 No N/A
Hindlimb 3 No N/A
Hippocampus 3 No N/A
Hypothalamus 3 No N/A
Ileum 3 No  (14/127)  (1/3) N/A
Jejunum 3 No  (6/127) N/A
Kidney 3 No  (18/584)  (1/3) N/A
Large intestine 3 No  (10/584) N/A
Liver 3 No N/A
Lower urinary tract 3 No N/A
Lung 3 No N/A
Lymph node 3 No N/A
Mammary gland 3 No N/A
Mesenteric adipose tissue 3 No N/A
Mesenteric lymph node 3 No N/A
Midbrain 3 No  (3/3) N/A
Olfactory lobe 3 No N/A
Ovary 3 No  (1/584) N/A
Oviduct 3 No N/A
Pancreas 3 No  (5/584) N/A
Parathyroid gland 3 No N/A
Parotid gland 3 No N/A
Penis 3 No N/A
Peripheral nervous system 3 No N/A
Peyer's patch 3 No N/A
Pituitary gland 3 No N/A
Prostate gland 3 No  (12/584)  (1/3) N/A
Quadriceps 3 No N/A
Sciatic nerve 3 No N/A
Skeletal muscle 3 No N/A
Skin 3 No N/A
Small intestine 3 No  (9/584) N/A
Spinal cord 3 No  (3/3) N/A
Spleen 3 No  (2/584) N/A
Stomach 3 No  (12/584)  (1/3) N/A
Stomach pyloric region 3 No N/A
Striatum 3 No N/A
Sublingual gland 3 No N/A
Submandibular gland 3 No  (2/132) N/A
Testis 3 No  (2/584) N/A
Thymus 3 No N/A
Thyroid gland 3 No  (15/584)  (1/3) N/A
Tongue 3 No  (5/127) N/A
Trachea 3 No N/A
Trigeminal V nerve 3 No N/A
Urinary bladder 3 No N/A
Uterus 3 No N/A
Vagina 3 No N/A
Vas deferens 3 No  (15/388)  (2/3) N/A
Vascular system 3 No N/A
Vesicular gland 3 No N/A
White adipose tissue 3 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51) N/A
Brain 4  (6/485) N/A
Central nervous system ganglion 2  (1/51) N/A
Ear 4  (1/485) N/A
Embryo 4  (1/485)  (2/10) N/A
Eye 4  (1/485) N/A
Foot 4  (1/485) N/A
Forebrain 4  (1/485) N/A
Forelimb 4  (1/485) N/A
Gut 2  (1/50) N/A
Hand 4  (1/485) N/A
Head 4  (5/485) N/A
Heart 4  (1/485) N/A
Hindbrain 4  (6/485)  (2/10) N/A
Hindlimb 4  (1/485) N/A
Liver 4  (1/485) N/A
Lung 4  (1/485) N/A
Mandibular process 4  (1/485) N/A
Maxillary process 4  (1/485) N/A
Midbrain 4  (1/485) N/A
Nose 2  (1/51) N/A
Oral cavity 4  (1/485) N/A
Skeleton 2  (1/51) N/A
Skin 4  (1/485) N/A
Spinal cord 2  (1/50)  (2/2) N/A
Tail 4  (1/485) N/A
Tail somite 4  (1/485) N/A
Trachea 2  (1/50) N/A
Urinary system 2  (1/50) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
36 Images
Gross Morphology Embryo E9.5
2 Images
X-ray: XRay Images Dorso Ventral
40 Images
X-ray: XRay Images Lateral Orientation
20 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Slc6a5tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Slc6a5tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue

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