Genes Phenotypes

Gene: Rbl2

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Name
RB transcriptional corepressor like 2
MGI ID
MGI:105085
Synonyms
retinoblastoma-like 2 p130 Rb2
Viability
Homozygous - Subviable
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (3) Measurements chart (102) All data table (108)
Expression & images (74) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal retina morphology Rbl2tm1b(EUCOMM)Hmgu HET postnatal 7.38×10-05
preweaning lethality, incomplete penetrance Rbl2tm1b(EUCOMM)Hmgu HOM n/a 0.00
persistence of hyaloid vascular system Rbl2tm1b(EUCOMM)Hmgu HET postnatal 4.77×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Bone 2 No  (2/2) N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No  (2/2) N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No  (1/2) N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No  (2/2) N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No  (2/2) N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No  (2/2) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2) N/A
LacZ Wholemount Images
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/485)  (2/3) N/A
Dorsal root ganglion 1  (1/47) Image Only N/A
Ear 1  (1/485) Image Only N/A
Embryo 1  (1/485)  (2/3)  Wholemount images
Eye 1  (1/485)  (2/3) N/A
Foot 1  (1/485) Image Only N/A
Forebrain 1  (1/485)  (1/3) N/A
Forelimb 1  (1/485)  (2/3) N/A
Fronto-nasal process 1  (1/48) Image Only N/A
Hand 1  (1/485)  (2/3) N/A
Head 1  (5/485)  (2/3) N/A
Heart 1  (1/485)  (2/3) N/A
Hindbrain 1  (6/485)  (2/3) N/A
Hindlimb 1  (1/485) Image Only N/A
Liver 1  (1/485) N/A
Lung 1  (1/485) Image Only N/A
Mandibular process 1  (1/485)  (2/3) N/A
Maxillary process 1  (1/485)  (2/3) N/A
Midbrain 1  (1/485)  (1/3) N/A
Nose 1  (1/51)  (2/3) N/A
Oral cavity 1  (1/485) Image Only N/A
Skin 1  (1/485) Image Only N/A
Spinal cord 1  (1/50)  (2/3) N/A
Tail 1  (1/485)  (2/3) N/A
Tail somite 1  (1/485) Image Only N/A
embryo or Unassigned (12)
Embryo expression
EMAPA:16039 embryo

 Associated Images

Embryo LacZ: LacZ images wholemount
12 Images
X-ray: XRay Images Skull Lateral Orientation
8 Images
Sleep Wake: Wake state (bmp file)
1 Images
X-ray: XRay Images Dorso Ventral
9 Images
X-ray: XRay Images Lateral Orientation
9 Images
X-ray: XRay Images Forepaw
7 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
7 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Rbl2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Rbl2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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