Gene: Ubp1

Name
upstream binding protein 1
MGI ID
MGI:104889
Synonyms
NF2d9 LBP-1b LBP-1a
Viability
Homozygous - Lethal
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to tooth bud stage Ubp1tm1b(KOMP)Mbp HOM embryonic day 12.5 0.00
increased cardiac output Ubp1tm1b(KOMP)Mbp HET postnatal 7.31×10-06
preweaning lethality, complete penetrance Ubp1tm1b(KOMP)Mbp HOM n/a 0.00
decreased lean body mass Ubp1tm1b(KOMP)Mbp HET postnatal 4.58×10-05

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cecum 2 No  (12/383) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2)  Wholemount images
Trachea 2 No  (2/2)  Wholemount images
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/388)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2  (1/47)  (2/2) N/A
Axial skeleton 2  (1/51)  (2/2) N/A
Brain 2  (6/485)  (2/2) N/A
Central nervous system ganglion 2  (1/51)  (2/2) N/A
Cranium 2  (1/46)  (2/2) N/A
Dorsal root ganglion 2  (1/47)  (2/2) N/A
Ear 2  (1/485)  (2/2) N/A
Embryo 2  (1/485)  (2/2) N/A
Outer ear 2  (1/47)  (2/2) N/A
Eye 2  (1/485)  (2/2) N/A
Femur pre-cartilage condensation 2  (1/46)  (2/2) N/A
Foot 2  (1/485)  (2/2) N/A
Forearm 2  (1/282)  (2/2) N/A
Forebrain 2  (1/485)  (2/2) N/A
Forelimb 2  (1/485)  (2/2) N/A
Fronto-nasal process 2  (1/48)  (2/2) N/A
Gut 2  (1/50)  (2/2) N/A
Hand 2  (1/485)  (2/2) N/A
Head 2  (5/485)  (2/2) N/A
Head mesenchyme 2  (1/47)  (2/2) N/A
Heart 2  (1/485)  (2/2) N/A
Heart ventricle 2  (1/47)  (2/2) N/A
Hindbrain 2  (6/485)  (2/2) N/A
Hindlimb 2  (1/485)  (2/2) N/A
Humerus pre-cartilage condensation 2  (1/46)  (2/2) N/A
Inner ear 2  (1/46)  (2/2) N/A
Intestine 2  (1/47)  (2/2) N/A
Liver 2  (1/485)  (2/2) N/A
Lower leg 2  (1/282)  (2/2) N/A
Lung 2  (1/485)  (2/2) N/A
Mandibular process 2  (1/485)  (2/2) N/A
Maxillary process 2  (1/485)  (2/2) N/A
Mesonephros of female 2  (1/46)  (1/2) N/A
Mesonephros of male 2  (1/46)  (1/2) N/A
Metanephros 2  (1/46)  (2/2) N/A
Midbrain 2  (1/485)  (2/2) N/A
Nasal septum 2  (1/47)  (2/2) N/A
Nose 2  (1/51)  (2/2) N/A
Notochord 2  (1/47)  (2/2) N/A
Oral cavity 2  (1/485)  (2/2) N/A
Outflow tract 2  (1/47)  (2/2) N/A
Pancreas 2  (1/46)  (2/2) N/A
Pericardium 2  (1/46)  (2/2) N/A
Pharynx 2  (1/46)  (2/2) N/A
Radius-ulna pre-cartilage condensation 2  (1/46)  (2/2) N/A
Rib pre-cartilage condensation 2  (1/46)  (2/2) N/A
Skeleton 2  (1/51)  (2/2) N/A
Skin 2  (1/485)  (2/2) N/A
Spinal cord 2  (1/50)  (2/2) N/A
Stomach 2  (1/46)  (2/2) N/A
Tail 2  (1/485)  (2/2) N/A
Tail somite 2  (1/485)  (2/2) N/A
Thoracic vertebral cartilage condensation 2  (1/46)  (2/2) N/A
Tongue 2  (1/46)  (2/2) N/A
Trachea 2  (1/50)  (2/2) N/A
Trunk mesenchyme 2  (1/47)  (2/2) N/A
Umbilical artery embryonic part 2  (1/47)  (2/2) N/A
Umbilical vein embryonic part 2  (1/47)  (2/2) N/A
Upper arm 2  (1/282)  (2/2) N/A
Upper leg 2  (1/282)  (2/2) N/A
Urinary system 2  (1/50)  (2/2) N/A
Vibrissa 2  (1/47)  (2/2) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
9 Images
Eye Morphology: VIP of left eye
1 Images
Eye Morphology: VIP of right fundus
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Ubp1tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Ubp1tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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