Gene: Gpx5

Name
glutathione peroxidase 5
MGI ID
MGI:104886
Synonyms
Arep
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

Mouseover the data points for more information. Click and drag to zoom the chart. Click on the legends to disable/enable data.

Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Alanine aminotransferase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.425 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Electrocardiogram (ECG) / RR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.986 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Creatinine HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0189 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Number of thoracic vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_014_001'.
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Mean cell hemoglobin concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00347 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Radius HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Fibula HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Mean platelet volume HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000203 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Eosinophil differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000987 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Open Field / Percentage center time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.851 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Shape of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / Body length HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.459 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Brachydactyly HOM 5f:5m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Scapulae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Eye Morphology / Lens Opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Open Field / Periphery distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.200 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Eye Morphology / Retina (combined) HOM 8f:8m Not processed Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Zygomatic bone HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Calcium HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0811 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Shape of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Hematocrit HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0262 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.113 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.101 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / Fat mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00638 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 0.00857 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Phosphorus HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.358 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Tremor HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Viability Primary Screen / Outcome HOM 49f:73m Supplied as data Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Lymphocyte cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.741 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Electrocardiogram (ECG) / ST HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.323 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Indirect Calorimetry / Respiratory Exchange Ratio HOM 0f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.973 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Open Field / Center distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.416 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 0.141 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Triglycerides HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.518 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Clavicle HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Platelet count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0909 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Digit integrity HOM 5f:5m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Total protein HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.181 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00672 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Number of cervical vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_013_001'.
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Fusion of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Tibia HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Aspartate aminotransferase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.368 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Eosinophil cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00255 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.786 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Hemoglobin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.432 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Open Field / Whole arena resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.919 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Syndactylism HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Eye Morphology / Lens HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.281 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Head size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Open Field / Center average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0684 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00353 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Neutrophil differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0821 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / HDL-cholesterol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.283 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Open Field / Periphery average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.259 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Processes on vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Maxilla/Pre-maxilla HOM 5f:5m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Lymphocyte differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00193 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Monocyte differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.865 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0114 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Number of ribs right HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_008_001'.
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Open Field / Distance travelled - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.211 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Snout size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Auditory Brain Stem Response / Click-evoked ABR threshold HOM 2f:2m 0.616 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Electrocardiogram (ECG) / PR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.681 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 0.0199 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Total cholesterol HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.523 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Open Field / Periphery permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.851 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Albumin HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.125 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.817 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Electrocardiogram (ECG) / HR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.963 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Aggression HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Pelvis HOM 5f:5m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Grip Strength / Forelimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.556 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Startle response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Mean cell volume HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.176 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Femur HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Eye Morphology / Cornea HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Open Field / Center permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.851 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Basophil cell count HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00674 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0595 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Red blood cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.129 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.312 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Eye Morphology / Retinal Blood Vessels HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Mandibles HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Neutrophil cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.274 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Humerus HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Number of digits HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_028_001'.
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.527 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Number of lumbar vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_015_001'.
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Ulna HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Alkaline phosphatase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.985 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Monocyte cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.535 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Open Field / Number of rears - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00737 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Teeth HOM 5f:5m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Number of ribs left HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_009_001'.
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / Bone Area HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00102 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Mean corpuscular hemoglobin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.141 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0198 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Total bilirubin HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.399 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Fusion of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.463 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Basophil differential count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.000563 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Clinical Chemistry / Glucose HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0364 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Eye Morphology / Retinal Blood Vessels Structure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Joints HOM 5f:5m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Skull shape HOM 5f:5m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Gait HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / Red blood cell distribution width HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.610 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Electrocardiogram (ECG) / QRS HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.799 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Ears HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Gpx5tm1.1(KOMP)Vlcg UC Davis Insulin Blood Level / Insulin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.118 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Body Composition (DEXA lean/fat) / Lean mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0992 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Open Field / Whole arena average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.211 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Eye Morphology / Corneal opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis X-ray / Number of pelvic vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_016_001'.
Gpx5tm1.1(KOMP)Vlcg UC Davis Hematology / White blood cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.342 Success
Gpx5tm1.1(KOMP)Vlcg UC Davis Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No  (2/584) N/A
Aorta 1 No N/A
Blood 1 No N/A
Bone marrow 1 No N/A
Brain 1 No N/A
Brainstem 1 No N/A
Brown adipose tissue 1 No N/A
Cartilage tissue 1 No N/A
Cecum 1 No  (12/383) N/A
Cerebellum 1 No N/A
Cerebral cortex 1 No N/A
Chest bone 1 No N/A
Colon 1 No  (12/127) N/A
Diaphragm 1 No N/A
Duodenum 1 No  (2/127) N/A
Epididymis 1 No  (18/134)  (1/1) N/A
Esophagus 1 No  (7/415) N/A
Eye 1 No N/A
Gall bladder 1 No N/A
Gonadal fat pad 1 No N/A
Harderian gland 1 No N/A
Heart 1 No N/A
Hindlimb 1 No N/A
Hippocampus 1 No N/A
Hypothalamus 1 No N/A
Ileum 1 No  (14/127) N/A
Jejunum 1 No  (6/127) N/A
Kidney 1 No  (18/584) N/A
Large intestine 1 No  (10/584) N/A
Liver 1 No N/A
Lower urinary tract 1 No N/A
Lung 1 No N/A
Lymph node 1 No N/A
Mammary gland 1 No N/A
Mesenteric adipose tissue 1 No N/A
Mesenteric lymph node 1 No N/A
Midbrain 1 No N/A
Olfactory lobe 1 No N/A
Ovary 1 No  (1/584) N/A
Oviduct 1 No N/A
Pancreas 1 No  (5/584) N/A
Parathyroid gland 1 No N/A
Parotid gland 1 No N/A
Penis 1 No N/A
Peripheral nervous system 1 No N/A
Peyer's patch 1 No N/A
Pituitary gland 1 No N/A
Prostate gland 1 No  (12/584) N/A
Quadriceps 1 No N/A
Sciatic nerve 1 No N/A
Skeletal muscle 1 No N/A
Skin 1 No N/A
Small intestine 1 No  (9/584) N/A
Spinal cord 1 No N/A
Spleen 1 No  (2/584) N/A
Stomach 1 No  (12/584) N/A
Stomach pyloric region 1 No N/A
Striatum 1 No N/A
Sublingual gland 1 No N/A
Submandibular gland 1 No  (2/132) N/A
Testis 1 No  (2/584) N/A
Thymus 1 No N/A
Thyroid gland 1 No  (15/584) N/A
Tongue 1 No  (5/127) N/A
Trachea 1 No N/A
Trigeminal V nerve 1 No N/A
Urinary bladder 1 No N/A
Uterus 1 No N/A
Vagina 1 No N/A
Vas deferens 1 No  (15/388)  (1/1) N/A
Vascular system 1 No N/A
Vesicular gland 1 No N/A
White adipose tissue 1 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Dorso Ventral
8 Images
X-ray: XRay Images Lateral Orientation
12 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Gpx5tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Gpx5tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Gpx5tm38811(L1L2_gt0) Targeting vectors
Gpx5tm38811(L1L2_st0) Targeting vectors

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter