Genes Phenotypes

Gene: Akt2

Name
thymoma viral proto-oncogene 2
MGI ID
MGI:104874
Synonyms
PKBbeta PKB 2410016A19Rik
Viability
N/A
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (20) Measurements chart (161) All data table (343)
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased lean body mass Akt2tm1Wcs HOM postnatal 1.34×10-23
increased lean body mass Akt2tm1Wcs HET postnatal 8.81×10-06
decreased body length Akt2tm1Wcs HOM postnatal 2.35×10-11
increased total body fat amount Akt2tm1Wcs HOM postnatal 1.74×10-23
decreased lean body mass Akt2tm1Wcs HET postnatal 6.46×10-05
increased circulating LDL cholesterol level Akt2tm1Wcs HOM postnatal 1.79×10-06
decreased circulating cholesterol level Akt2tm1Wcs HOM postnatal 4.08×10-05
decreased bone mineral density Akt2tm1Wcs HOM postnatal 6.38×10-08
abnormal bone mineralization Akt2tm1Wcs HOM postnatal 4.90×10-17
thrombocytosis Akt2tm1Wcs HOM postnatal 8.08×10-07
increased circulating alkaline phosphatase level Akt2tm1Wcs HOM postnatal 9.10×10-07
decreased body weight Akt2tm1Wcs HET postnatal 1.82×10-21
decreased circulating triglyceride level Akt2tm1Wcs HOM postnatal 3.67×10-11
decreased grip strength Akt2tm1Wcs HOM postnatal 2.11×10-05
decreased body weight Akt2tm1Wcs HOM postnatal 0.00
abnormal glucose homeostasis Akt2tm1Wcs HOM postnatal 4.66×10-09
decreased circulating LDL cholesterol level Akt2tm1Wcs HOM postnatal 1.79×10-06
increased circulating cholesterol level Akt2tm1Wcs HOM postnatal 4.08×10-05
increased total body fat amount Akt2tm1Wcs HET postnatal 6.52×10-06
decreased lean body mass Akt2tm1Wcs HOM postnatal 2.64×10-15

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

Legacy Phenotype Associated Images
Akt2tm1e(KOMP)Wtsi
HOM, Male, WTSI
Akt2tm1e(KOMP)Wtsi
HET, Female, WTSI
Akt2tm1e(KOMP)Wtsi
HOM, Female, WTSI
Akt2tm1e(KOMP)Wtsi
HET, Female, WTSI
Akt2tm1e(KOMP)Wtsi
HET, Female, WTSI

View all 167 images

Akt2tm1e(KOMP)Wtsi
tail skin, HET, Male, WTSI
Akt2tm1e(KOMP)Wtsi
tail skin, HOM, Female, WTSI
Akt2tm1e(KOMP)Wtsi
tail skin, HOM, Female, WTSI
Akt2tm1e(KOMP)Wtsi
tail skin, HOM, Female, WTSI
Akt2tm1e(KOMP)Wtsi
tail skin, HOM, Female, WTSI

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Akt2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Akt2tm40417(L1L2_gt0) Targeting vectors

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