Genes Phenotypes

Gene: Akt2

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Name
thymoma viral proto-oncogene 2
MGI ID
MGI:104874
Synonyms
PKBbeta 2410016A19Rik PKB
Viability
N/A
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (20) Measurements chart (150) All data table (365)
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased grip strength Akt2tm1Wcs HOM Early adult 2.11×10-05
increased total body fat amount Akt2tm1Wcs HOM Early adult 1.74×10-23
increased circulating LDL cholesterol level Akt2tm1Wcs HOM Early adult 1.79×10-06
decreased body weight Akt2tm1Wcs HET Early adult 1.82×10-21
decreased lean body mass Akt2tm1Wcs HET Early adult 6.46×10-05
increased circulating cholesterol level Akt2tm1Wcs HOM Early adult 4.08×10-05
decreased lean body mass Akt2tm1Wcs HOM Early adult 2.64×10-15
decreased circulating triglyceride level Akt2tm1Wcs HOM Early adult 3.67×10-11
abnormal glucose homeostasis Akt2tm1Wcs HOM Early adult 4.66×10-09
increased lean body mass Akt2tm1Wcs HET Early adult 8.81×10-06
decreased body weight Akt2tm1Wcs HOM Early adult 0.00
increased total body fat amount Akt2tm1Wcs HET Early adult 6.52×10-06
abnormal bone mineralization Akt2tm1Wcs HOM Early adult 4.90×10-17
decreased circulating LDL cholesterol level Akt2tm1Wcs HOM Early adult 1.79×10-06
thrombocytosis Akt2tm1Wcs HOM Early adult 8.08×10-07
increased lean body mass Akt2tm1Wcs HOM Early adult 1.34×10-23
decreased bone mineral density Akt2tm1Wcs HOM Early adult 6.38×10-08
increased circulating alkaline phosphatase level Akt2tm1Wcs HOM Early adult 9.10×10-07
decreased circulating cholesterol level Akt2tm1Wcs HOM Early adult 4.08×10-05
decreased body length Akt2tm1Wcs HOM Early adult 2.35×10-11

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 Expression

Expression data not available

 Associated Images

Legacy Phenotype Associated Images
Akt2tm1e(KOMP)Wtsi
HOM, Male, WTSI
Akt2tm1e(KOMP)Wtsi
HOM, Male, WTSI
Akt2tm1e(KOMP)Wtsi
HOM, Male, WTSI
Akt2tm1e(KOMP)Wtsi
HOM, Male, WTSI
Akt2tm1e(KOMP)Wtsi
HOM, Male, WTSI

View all 167 images

Akt2tm1e(KOMP)Wtsi
tail skin, HET, Male, WTSI
Akt2tm1e(KOMP)Wtsi
tail skin, HOM, Female, WTSI
Akt2tm1e(KOMP)Wtsi
tail skin, HOM, Female, WTSI
Akt2tm1e(KOMP)Wtsi
tail skin, HOM, Female, WTSI
Akt2tm1e(KOMP)Wtsi
tail skin, HOM, Female, WTSI

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Akt2tm40417(L1L2_gt0) Targeting vectors
Akt2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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