Genes Phenotypes

Gene: Lcp1

Name
lymphocyte cytosolic protein 1
MGI ID
MGI:104808
Synonyms
L-fimbrin D14Ertd310e Pls2 L-plastin
Viability
Homozygous - Lethal
Other links
MGI   Ensembl  
Significant phenotypes (3) All measurements (282) Expression & images (73) Disease models (0) Order (5)
View data by physiological system
Significant
Not Significant
Not tested
Body weight
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal sleep behavior Lcp1tm1e.1(KOMP)Wtsi HET postnatal 2.77×10-06
increased fasted circulating glucose level Lcp1tm1e.1(KOMP)Wtsi HET postnatal 3.45×10-05
preweaning lethality, complete penetrance Lcp1tm1e.1(KOMP)Wtsi HOM n/a 0.00

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No  (2/2)  Section images
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584)  (1/2)  Section images
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No  Section images
Mammary gland 2 No N/A
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (1/2)  Section images
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No  Section images
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584) N/A
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
digestive system (2)
Large Intestine expression
MA:0000333
immune system (2)
Lymph Node imageOnly
MA:0000139
nervous system (3)
Brain expression
MA:0000168
postnatal mouse (6)
Brain expression
MA:0000168
trunk (2)
Large Intestine expression
MA:0000333
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (2/2) N/A
Dorsal root ganglion 2  (1/47) N/A
Ear 2  (1/485)  (1/2) N/A
Embryo 2  (1/485)  (2/2)  Wholemount images
Eye 2  (1/485)  (1/2) N/A
Foot 2  (1/485)  (1/2) N/A
Forebrain 2  (1/485)  (2/2) N/A
Forelimb 2  (1/485)  (1/2) N/A
Fronto-nasal process 2  (1/48) Image Only N/A
Hand 2  (1/485)  (1/2) N/A
Head 2  (5/485)  (2/2) N/A
Heart 2  (1/485)  (1/2) N/A
Hindbrain 2  (6/485)  (2/2) N/A
Hindlimb 2  (1/485)  (1/2) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) Image Only N/A
Mandibular process 2  (1/485)  (1/2) N/A
Maxillary process 2  (1/485)  (1/2) N/A
Midbrain 2  (1/485)  (1/2) N/A
Nose 2  (1/51)  (2/2) N/A
Oral cavity 2  (1/485) Image Only N/A
Skin 2  (1/485)  (1/2) N/A
Spinal cord 2  (1/50)  (1/2) N/A
Tail 2  (1/485)  (1/2) N/A
Tail somite 2  (1/485)  (1/2) N/A
embryo or Unassigned (4)
Embryo expression
EMAPA:16039 embryo

 Associated Images

Electroretinography 2: Rod and cone PDF
4 Images
Sleep Wake: Wake state (bmp file)
10 Images
Original Image
Adult LacZ: LacZ Images Section
6 Images
Embryo LacZ: LacZ images wholemount
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Lcp1tm1e.1(KOMP)Wtsi Mice
Lcp1tm1e(KOMP)Wtsi Targeted, non-conditional allele Mice
Lcp1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Lcp1tm43058(L1L2_Bact_P) Targeting vectors
Lcp1tm43058(L1L2_gt1) Targeting vectors

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