Genes Phenotypes

Gene: Myo6

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Name
myosin VI
MGI ID
MGI:104785
Synonyms
Myo6 Tlc rsv
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (20) Measurements chart (558) All data table (798)
Expression & images (0) Disease models (0) Order (4)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
head bobbing Myo6em1(IMPC)Tcp HOM Early adult 2.69×10-17
abnormal behavior Myo6em1(IMPC)Tcp HOM Early adult 1.07×10-16
decreased circulating amylase level Myo6Tlc HET Early adult 2.60×10-08
hyperactivity Myo6Tlc HET Early adult 1.09×10-06
decreased circulating triglyceride level Myo6Tlc HET Early adult 6.19×10-06
hyperactivity Myo6em1(IMPC)Tcp HOM Early adult 1.55×10-19
abnormal startle reflex Myo6em1(IMPC)Tcp HOM Early adult 1.19×10-14
abnormal whole-body plethysmography Myo6Tlc HET Early adult 4.89×10-06
decreased lean body mass Myo6em1(IMPC)Tcp HOM Early adult 9.63×10-06
increased vertical activity Myo6Tlc HET Early adult 7.72×10-05
increased or absent threshold for auditory brainstem response Myo6em1(IMPC)Tcp HOM Early adult 5.10×10-06
decreased body length Myo6em1(IMPC)Tcp HOM Early adult 9.20×10-21
decreased total body fat amount Myo6em1(IMPC)Tcp HOM Early adult 1.10×10-12
decreased grip strength Myo6em1(IMPC)Tcp HOM Early adult 4.38×10-10
decreased body weight Myo6Tlc HET Early adult 2.14×10-06
abnormal gait Myo6em1(IMPC)Tcp HOM Early adult 2.53×10-10
decreased bone mineral content Myo6em1(IMPC)Tcp HOM Early adult 3.01×10-21
decreased bone mineral density Myo6em1(IMPC)Tcp HOM Early adult 1.53×10-22
abnormal bone structure Myo6em1(IMPC)Tcp HOM Early adult 1.29×10-13
increased lean body mass Myo6em1(IMPC)Tcp HOM Early adult 9.54×10-08

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
6 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Legacy Phenotype Associated Images
Myo6sv
HET, Male, WTSI
Myo6sv
HET, Male, WTSI
Myo6sv
HET, Male, WTSI
Myo6sv
HET, Male, WTSI
Myo6sv
body, HET, Male, WTSI

View all 165 images

Myo6sv
abnormal hair cycle, HOM, Female, WTSI
Myo6sv
tail skin, HET, Female, WTSI
Myo6sv
abnormal hair follicle bulge morphology, HOM, Female, WTSI
Myo6sv
tail skin, HET, Female, WTSI

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Myo6em1(IMPC)Tcp Exon Deletion Mice
Myo6tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Myo6tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Myo6tm40489(L1L2_gt0) Targeting vectors