Gene: Gpx4

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Name
glutathione peroxidase 4
MGI ID
MGI:104767
Synonyms
mtPHGPx PHGPx snGPx phospholipid hydroperoxide glutathione peroxidase sperm nuclei glutathione peroxidase
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to tooth bud stage Gpx4tm1.1(KOMP)Vlcg HOM E12.5 0.00
preweaning lethality, complete penetrance Gpx4tm1.1(KOMP)Vlcg HOM Early adult 0.00
hydrometra Gpx4tm1.1(KOMP)Vlcg HET Early adult 0.00
abnormal heart morphology Gpx4tm1.1(KOMP)Vlcg HET Early adult 0.00
embryonic lethality prior to organogenesis Gpx4tm1.1(KOMP)Vlcg HOM E9.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379) N/A
Cerebellum 2 No  (2/2)  Section images
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (2/127) N/A
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415) N/A
Eye 2 No  (2/2)  Section images
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127)  (1/2)  Section images
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No  (1/2)  Section images
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Parotid gland 2 No N/A
Penis 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584)  (1/2)  Section images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Tongue 2 No  (5/127) N/A
Trachea 2 No N/A
Trigeminal V nerve 2 No  (2/2)  Section images
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/388)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Section
24 Images
X-ray: XRay Images Whole Body Dorso Ventral
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
8 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Gpx4tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Gpx4tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Gpx4tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Gpx4tm220805(L1L2_Bact_P) Targeting vectors

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