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Gene: Sez6 MGI:104745

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Gene Summary

Name:
seizure related gene 6
Synonyms:
D11Bhm177e,  sez-6

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IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Whole Body Lateral Orientation

12 Images

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X-ray

XRay Images Whole Body Dorso Ventral

12 Images

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Human diseases caused by Sez6 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Sez6 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Progressive Supranuclear Palsy
Unsteady gait, Abnormal synaptic transmission, Bradykinesia, Dementia, Falls, Cognitive impairmen... ORPHA:683

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Sez6

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Sez6.

No publications found that use IMPC mice or data for Sez6.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Sez6em1(IMPC)H Exon Deletion Mice
Sez6em2(IMPC)H Exon Deletion Mice
Sez6tm3(L1L2_gt1) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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