Gene: Cdkn2a

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Name
cyclin dependent kinase inhibitor 2A
MGI ID
MGI:104738
Synonyms
INK4a-ARF p16INK4a p19ARF MTS1 p16 ARF-INK4a Arf Pctr1 p19 Ink4a/Arf
Viability
N/A
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
cataract Cdkn2atm1a(EUCOMM)Wtsi HOM Early adult 6.17×10-09
abnormal eye morphology Cdkn2atm1a(EUCOMM)Wtsi HOM Early adult 1.88×10-07
abnormal lens morphology Cdkn2atm1a(EUCOMM)Wtsi HOM Early adult 6.53×10-09

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/589) N/A
Aorta 2 No  (1/589) N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (3/589) N/A
Brainstem 2 No  (2/589) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/589) N/A
Cerebral cortex 2 No  (2/589) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/589) N/A
Hippocampus 2 No  (3/589) N/A
Hypothalamus 2 No  (2/589) N/A
Kidney 2 No  (20/589) N/A
Large intestine 2 No  (10/589) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/589) N/A
Lung 2 No  (1/589) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Esophagus 2 No N/A
Olfactory lobe 2 No  (2/589) N/A
Ovary 2 No  (1/589) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/589) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (1/589) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/589) N/A
Prostate gland 2 No  (12/589) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/589) N/A
Spinal cord 2 No  (2/589) N/A
Spleen 2 No  (2/589) N/A
Stomach 2 No  (13/589) N/A
Striatum 2 No  (3/589) N/A
Testis 2 No  (5/589)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (16/589) N/A
Trachea 2 No  (2/589) N/A
Uterus 2 No N/A
White adipose tissue 2 No N/A
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

Histopathology
19 Images
Legacy Phenotype Associated Images

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 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Eye with optic nerve - developmental and structural abnormality Cdkn2atm1a(EUCOMM)Wtsi HOM Early adult
Testes - process of degenerative change Cdkn2atm1a(EUCOMM)Wtsi HOM Early adult
Thymus - developmental and structural abnormality Cdkn2atm1a(EUCOMM)Wtsi HOM Early adult
Thymus - MPATH diagnostic term cyst Cdkn2atm1a(EUCOMM)Wtsi HOM Early adult

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MGI Allele Allele Type Produced
Cdkn2atm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells