Gene: Fgf9

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Name
fibroblast growth factor 9
MGI ID
MGI:104723
Synonyms
Eks glia activating factor
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal body wall morphology Fgf9tm1b(KOMP)Wtsi HOM E18.5 0.00
abnormal retinal vasculature morphology Fgf9tm1b(KOMP)Wtsi HET Early adult 1.02×10-19
embryonic lethality prior to tooth bud stage Fgf9tm1b(KOMP)Wtsi HOM E12.5 0.00
increased startle reflex Fgf9tm1b(KOMP)Wtsi HET Early adult 1.66×10-05
preweaning lethality, complete penetrance Fgf9tm1b(KOMP)Wtsi HOM Early adult 0.00
cleft palate Fgf9tm1b(KOMP)Wtsi HOM E18.5 0.00
decreased hematocrit Fgf9tm1b(KOMP)Wtsi HET Early adult 9.15×10-05
abnormal embryo size Fgf9tm1b(KOMP)Wtsi HOM E18.5 0.00
increased mean corpuscular hemoglobin concentration Fgf9tm1b(KOMP)Wtsi HET Early adult 8.98×10-05
enlarged heart Fgf9tm1b(KOMP)Wtsi HET Early adult 0.00
hyperactivity Fgf9tm1b(KOMP)Wtsi HET Early adult 3.02×10-05
cataract Fgf9tm1b(KOMP)Wtsi HET Early adult 2.08×10-16
increased grip strength Fgf9tm1b(KOMP)Wtsi HET Early adult 1.33×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584)  (2/4)  Wholemount images
Aorta 4 No N/A
Bone 2 No  (2/2)  Wholemount images
Brain 4 No  (4/4)  Wholemount images
Brainstem 4 No  (4/4)  Wholemount images
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No  (2/4)  Wholemount images
Cerebellum 4 No  (4/4)  Wholemount images
Cerebral cortex 4 No  (2/4)  Wholemount images
Epididymis 2 No  (18/134) N/A
Esophagus 4 No  (7/415) N/A
Eye 4 No  (2/4)  Wholemount images
Gall bladder 2 No N/A
Heart 4 No N/A
Hippocampus 4 No  (4/4)  Wholemount images
Hypothalamus 4 No  (2/4)  Wholemount images
Kidney 4 No  (18/584)  (4/4)  Wholemount images
Large intestine 4 No  (10/584) N/A
Liver 4 No N/A
Lower urinary tract 4 No  (2/4)  Wholemount images
Lung 4 No N/A
Lymph node 4 No N/A
Mammary gland 4 No N/A
Midbrain 2 No N/A
Olfactory lobe 4 No  (2/4)  Wholemount images
Oral epithelium 2 No N/A
Ovary 4 No  (1/584)  (1/4)  Wholemount images
Oviduct 4 No  (1/4)  Wholemount images
Pancreas 4 No  (5/584) N/A
Parathyroid gland 2 No  (1/2)  Wholemount images
Peripheral nervous system 4 No  (2/4)  Wholemount images
Peyer's patch 4 No N/A
Pituitary gland 4 No  (1/4)  Wholemount images
Prostate gland 4 No  (12/584) N/A
Skeletal muscle 4 No N/A
Skin 4 No  (2/4)  Wholemount images
Small intestine 4 No  (9/584) N/A
Spinal cord 4 No  (4/4)  Wholemount images
Spleen 4 No  (2/584) N/A
Stomach 4 No  (12/584) N/A
Striatum 4 No  (2/4)  Wholemount images
Submandibular gland 2 No  (2/132) N/A
Testis 4 No  (2/584)  (1/4)  Wholemount images
Thalamus 2 No N/A
Thymus 4 No N/A
Thyroid gland 4 No  (15/584) N/A
Trachea 4 No  (2/4)  Wholemount images
Urinary bladder 2 No N/A
Uterus 4 No N/A
Vascular system 4 No N/A
Vesicular gland 2 No N/A
White adipose tissue 4 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 1  (1/61)  (1/1) N/A
Brain 2  (6/504) N/A
Dorsal root ganglion 1  (1/57) N/A
Ear 2  (1/504)  (1/3) N/A
Embryo 2  (1/505)  (3/3)  Wholemount images
Eye 2  (1/504)  (3/3) N/A
Foot 2  (1/504)  (2/3) N/A
Forebrain 2  (1/504) N/A
Forelimb 2  (1/504)  (3/3) N/A
Fronto-nasal process 1  (1/58) Image Only N/A
Hand 2  (1/503)  (2/3) N/A
Head 2  (5/504)  (3/3) N/A
Heart 2  (1/504) N/A
Hindbrain 2  (6/504) N/A
Hindlimb 2  (1/503)  (3/3) N/A
Liver 2  (1/504) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504) N/A
Maxillary process 2  (1/504)  (1/3) N/A
Midbrain 2  (1/504) N/A
Nose 1  (1/70)  (1/1) N/A
Oral cavity 2  (1/504) N/A
Rib pre-cartilage condensation 1  (1/54)  (1/1) N/A
Skin 2  (1/504)  (1/3) N/A
Spinal cord 1  (1/69) N/A
Tail 2  (1/504)  (3/3) N/A
Tail somite 2  (1/504) N/A

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
21 Images
X-ray: XRay Images Whole Body Dorso Ventral
21 Images
Electroretinography 2: Rod and cone PDF
4 Images
Eye Morphology: Images Ophthalmoscopy
4 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
21 Images
Gross Morphology Embryo E18.5
6 Images
Embryo LacZ: LacZ images wholemount
12 Images
Adult LacZ: LacZ Images Wholemount
14 Images

 Disease Models

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MGI Allele Allele Type Produced
Fgf9tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Fgf9tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice