Meis1 - Meis homeobox 1 | International Mouse Phenotyping Consortium

Phenotype	Allele	Zyg	Life Stage	P Value
decreased prepulse inhibition	Meis1^{tm1b(EUCOMM)Hmgu}	HET	postnatal	8.11×10^-05
increased bone mineral content	Meis1^{tm1b(EUCOMM)Hmgu}	HET	postnatal	2.48×10^-07
increased startle reflex	Meis1^{tm1b(EUCOMM)Hmgu}	HET	postnatal	6.99×10^-09
preweaning lethality, complete penetrance	Meis1^{tm1b(EUCOMM)Hmgu}	HOM	n/a	0.00

Table Images

Expression No Expression Ambiguous No Tissue Available

Anatomy	#HET Specimens	HOM Images?	WT Expr	Mutant Expr	Images
Adrenal gland	2	No	(2/584)		N/A
Aorta	2	No			N/A
Brain	2	No			N/A
Brainstem	2	No			N/A
Brown adipose tissue	2	No			N/A
Cartilage tissue	2	No		(2/2)	Section images
Cerebellum	2	No			N/A
Cerebral cortex	2	No			N/A
Epididymis	2	No	(18/134)		N/A
Esophagus	2	No	(7/415)	(2/2)	Section images
Eye	2	No			N/A
Heart	2	No		(2/2)	Section images
Hippocampus	2	No			N/A
Hypothalamus	2	No			N/A
Kidney	2	No	(18/584)		N/A
Large intestine	2	No	(10/584)	(2/2)	Section images
Liver	2	No			N/A
Lower urinary tract	2	No			N/A
Lung	2	No			N/A
Lymph node	2	No			N/A
Mammary gland	2	No			N/A
Midbrain	2	No			N/A
Olfactory lobe	2	No			N/A
Ovary	2	No	(1/584)	(1/2)	Section images
Oviduct	2	No		(1/2)	Section images
Pancreas	2	No	(5/584)	(2/2)	Section images
Peripheral nervous system	2	No			N/A
Peyer's patch	2	No			N/A
Pituitary gland	2	No			N/A
Prostate gland	2	No	(12/584)		N/A
Skeletal muscle	2	No			N/A
Skin	2	No			N/A
Small intestine	2	No	(9/584)	(2/2)	Section images
Spinal cord	2	No			N/A
Spleen	2	No	(2/584)		N/A
Stomach	2	No	(12/584)	(2/2)	Section images
Striatum	2	No			N/A
Submandibular gland	2	No	(2/132)		N/A
Testis	2	No	(2/584)	(1/2)	Section images
Thalamus	2	No			N/A
Thymus	2	No			N/A
Thyroid gland	2	No	(15/584)		N/A
Trachea	2	No		(2/2)	Section images
Urinary bladder	2	No			Section images
Uterus	2	No		(1/2)	Section images
Vascular system	2	No			N/A
Vesicular gland	2	No			N/A
White adipose tissue	2	No			N/A

cardiovascular system (1)
Heart expression
MA:0000072

digestive system (4)
Esophagus expression
MA:0000352

postnatal mouse (13)
Cartilage tissue expression
MA:0000104

reproductive system (4)
Ovary expression
MA:0000384

respiratory system (1)
Trachea expression
MA:0000441

set of connective tissues (1)
Cartilage tissue expression
MA:0000104

trunk (12)
Esophagus expression
MA:0000352

urinary system (1)
Urinary bladder imageOnly
MA:0000380

Table Images

Expression No Expression Ambiguous No Tissue Available

Anatomy	#HET Specimens	WT Expr	Mutant Expr	Images
Brain	2	(6/485)	(2/3)	N/A
Dorsal root ganglion	2	(1/47)	Image Only	N/A
Ear	2	(1/485)		N/A
Embryo	2	(1/485)	(2/3)	Wholemount images
Eye	2	(1/485)	(2/3)	N/A
Foot	2	(1/485)		N/A
Forebrain	2	(1/485)		N/A
Forelimb	2	(1/485)	(2/3)	N/A
Fronto-nasal process	2	(1/48)	Image Only	N/A
Hand	2	(1/485)		N/A
Head	2	(5/485)	(2/3)	N/A
Heart	2	(1/485)	(2/3)	N/A
Hindbrain	2	(6/485)	(2/3)	N/A
Hindlimb	2	(1/485)	(2/3)	N/A
Liver	2	(1/485)		N/A
Lung	2	(1/485)	Image Only	N/A
Mandibular process	2	(1/485)	(2/3)	N/A
Maxillary process	2	(1/485)	(2/3)	N/A
Midbrain	2	(1/485)		N/A
Nose	2	(1/51)	(2/3)	N/A
Oral cavity	2	(1/485)	Image Only	N/A
Skin	2	(1/485)	(2/3)	N/A
Spinal cord	2	(1/50)	(2/3)	N/A
Tail	2	(1/485)	(2/3)	N/A
Tail somite	2	(1/485)	(2/3)	N/A

embryo or Unassigned (12)
Embryo expression
EMAPA:16039 embryo

MGI Allele	Allele Type	Availability
Meis1^{tm1a(EUCOMM)Hmgu}	KO first allele (reporter-tagged insertion with conditional potential)	Mice, Targeting vectors, ES Cells
Meis1^{tm1b(EUCOMM)Hmgu}	Reporter-tagged deletion allele (post-Cre)	Mice

MGI Allele

Allele Type

Availability

Meis1^{tm1a(EUCOMM)Hmgu}

KO first allele (reporter-tagged insertion with conditional potential)

Mice, Targeting vectors, ES Cells

Meis1^{tm1b(EUCOMM)Hmgu}

Reporter-tagged deletion allele (post-Cre)

Mice

Gene: Meis1