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Gene: Scnn1b

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Name
sodium channel, nonvoltage-gated 1 beta
MGI ID
MGI:104696
Synonyms
ENaC beta
Viability
Data available
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (2) Measurements chart (199) All data table (480)
Expression & images (67) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Scnn1btm1b(EUCOMM)Hmgu HOM   Early adult 0.00
abnormal pelvic girdle bone morphology Scnn1btm1b(EUCOMM)Hmgu HET Early adult 2.32×10-05

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Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583)  (1/2)  Wholemount images
Bone 2 No N/A
Brain 2 No  (4/583)  (1/2)  Wholemount images
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Esophagus 2 No  (7/407) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/583)  (1/2)  Wholemount images
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583)  (2/2)  Wholemount images
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583)  (1/2)  Wholemount images
Lung 2 No  (2/583)  (2/2)  Wholemount images
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/583) N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/583)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/583) N/A
Parathyroid gland 2 No  (1/563) N/A
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583)  (2/2)  Wholemount images
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583) N/A
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583)  (2/2)  Wholemount images
Striatum 2 No  (3/583) N/A
Testis 2 No  (6/583)  (1/2)  Wholemount images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583)  (2/2)  Wholemount images
Trachea 2 No  (3/583) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
cardiovascular system (1)
Heart expression
Aorta expression
MA:0000072
MA:0000062
digestive system (1)
Stomach expression
MA:0000353
endocrine system (1)
Thyroid gland expression
MA:0000129
nervous system (4)
Brain expression
MA:0000168
postnatal mouse (12)
Brain expression
MA:0000168
reproductive system (2)
Ovary ambiguous
Oviduct expression
MA:0000384
MA:0000385
respiratory system (1)
Lung expression
MA:0000415
trunk (6)
Heart expression
Aorta expression
MA:0000072
MA:0000062
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
1  (6/505) N/A
1  (1/505) N/A
1  (1/506)  (2/2) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (5/505) N/A
1  (1/505) N/A
1  (6/505) N/A
1  (1/505) N/A
1  (1/503) N/A
1  (1/503) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/503) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A

 Associated Images

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Adult LacZ: LacZ Images Wholemount
12 Images
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X-ray: XRay Images Whole Body Dorso Ventral
12 Images
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X-ray: XRay Images Whole Body Lateral Orientation
12 Images
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Echo: M-Mode Images
32 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
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Embryo LacZ: LacZ images wholemount
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Scnn1btm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Scnn1btm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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