Genes Phenotypes

Gene: Scnn1b

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Name
sodium channel, nonvoltage-gated 1 beta
MGI ID
MGI:104696
Synonyms
ENaC beta
Viability
Homozygous - Lethal
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (2) Measurements chart (243) All data table (434)
Expression & images (67) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Scnn1btm1b(EUCOMM)Hmgu HOM Early adult 0.00
abnormal pelvic girdle bone morphology Scnn1btm1b(EUCOMM)Hmgu HET Early adult 1.13×10-05

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Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No  (1/2)  Wholemount images
Bone 2 No N/A
Brain 2 No  (1/2)  Wholemount images
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/2)  Wholemount images
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/2)  Wholemount images
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2)  Wholemount images
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
cardiovascular system (1)
Aorta expression
Heart expression
MA:0000062
MA:0000072
digestive system (1)
Stomach expression
MA:0000353
endocrine system (1)
Thyroid gland expression
MA:0000129
nervous system (4)
Brain expression
MA:0000168
postnatal mouse (12)
Aorta expression
Heart expression
MA:0000062
MA:0000072
reproductive system (2)
Oviduct expression
Ovary ambiguous
MA:0000385
MA:0000384
respiratory system (1)
Lung expression
MA:0000415
trunk (6)
Aorta expression
Heart expression
MA:0000062
MA:0000072
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/504) N/A
Ear 1  (1/504) N/A
Embryo 1  (1/505)  (2/2) N/A
Eye 1  (1/504) N/A
Foot 1  (1/504) N/A
Forebrain 1  (1/504) N/A
Forelimb 1  (1/504) N/A
Hand 1  (1/503) N/A
Head 1  (5/504) N/A
Heart 1  (1/504) N/A
Hindbrain 1  (6/504) N/A
Hindlimb 1  (1/503) N/A
Liver 1  (1/504) N/A
Lung 1  (1/500) N/A
Mandibular process 1  (1/504) N/A
Maxillary process 1  (1/504) N/A
Midbrain 1  (1/504) N/A
Oral cavity 1  (1/504) N/A
Skin 1  (1/504) N/A
Tail 1  (1/504) N/A
Tail somite 1  (1/504) N/A

 Associated Images

Echo: M-Mode Images
32 Images
Embryo LacZ: LacZ images wholemount
8 Images
Adult LacZ: LacZ Images Wholemount
12 Images
X-ray: XRay Images Whole Body Lateral Orientation
12 Images
X-ray: XRay Images Whole Body Dorso Ventral
12 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Scnn1btm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Scnn1btm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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