Genes Phenotypes

Gene: Eps15

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Name
epidermal growth factor receptor pathway substrate 15
MGI ID
MGI:104583
Synonyms
2410112D09Rik
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (146) All data table (270)
Expression & images (45) Disease models (0) Order (3)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating LDL cholesterol level Eps15tm1a(KOMP)Wtsi HOM Early adult 5.58×10-05
decreased mean corpuscular hemoglobin Eps15tm1a(KOMP)Wtsi HOM Early adult 1.59×10-06
increased circulating HDL cholesterol level Eps15tm1a(KOMP)Wtsi HOM Early adult 5.99×10-05
decreased leukocyte cell number Eps15tm1a(KOMP)Wtsi HOM Early adult 6.21×10-05

Download data as:  TSV  XLS

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 0 No  (2/584)  (2/2) N/A
Aorta 0 No N/A
Blood vessel 0 No  (2/2) N/A
Bone 0 No N/A
Brain 0 No  (2/2) N/A
Brainstem 0 No N/A
Brown adipose tissue 0 No N/A
Cartilage tissue 0 No  (2/2) N/A
Cerebellum 0 No N/A
Cerebral cortex 0 No N/A
Eye 0 No  (2/2) N/A
Gall bladder 0 No  (2/2) N/A
Heart 0 No  (2/2) N/A
Hippocampus 0 No N/A
Hypothalamus 0 No N/A
Kidney 0 No  (18/584)  (2/2) N/A
Large intestine 0 No  (10/584)  (2/2) N/A
Liver 0 No N/A
Lower urinary tract 0 No  (2/2) N/A
Lung 0 No  (2/2) N/A
Lymph node 0 No  (2/2) N/A
Mammary gland 0 No N/A
Esophagus 0 No  (2/2) N/A
Olfactory lobe 0 No N/A
Ovary 0 No  (1/584)  (1/2) N/A
Oviduct 0 No  (1/2) N/A
Pancreas 0 No  (5/584)  (2/2) N/A
Parathyroid gland 0 No  (1/2) N/A
Peripheral nervous system 0 No  (2/2) N/A
Peyer's patch 0 No  (1/2) N/A
Pituitary gland 0 No  (2/2) N/A
Prostate gland 0 No  (12/584)  (1/2) N/A
Skeletal muscle tissue 0 No N/A
Skin 0 No  (2/2) N/A
Small intestine 0 No  (9/584)  (2/2) N/A
Spinal cord 0 No  (2/2) N/A
Spleen 0 No  (2/584)  (1/2) N/A
Stomach 0 No  (12/584)  (2/2) N/A
Striatum 0 No N/A
Testis 0 No  (2/584)  (1/2) N/A
Thymus 0 No  (2/2) N/A
Thyroid gland 0 No  (15/584)  (1/2) N/A
Trachea 0 No  (2/2) N/A
Uterus 0 No  (1/2) N/A
White adipose tissue 0 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Eps15tm1a(KOMP)Wtsi
spleen, HOM, Male, WTSI
Eps15tm1a(KOMP)Wtsi
brain, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
heart, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
eye, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
blood vessel, HOM, Female, WTSI

View all 25 images

Eps15tm1a(KOMP)Wtsi
spleen, HOM, Male, WTSI
Eps15tm1a(KOMP)Wtsi
heart, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
ovary, oviduct, uterus, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
lung, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
gall bladder, HOM, Female, WTSI

View all 16 images

Eps15tm1a(KOMP)Wtsi
gall bladder, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
large intestine, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
oesophagus, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
small intestine, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
brain, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
pituitary gland, peripheral nervous system, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
brain, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
spinal cord, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
spleen, HOM, Male, WTSI
Eps15tm1a(KOMP)Wtsi
lymph node, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
thymus, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
ovary, oviduct, uterus, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
prostate gland, HOM, Male, WTSI
Eps15tm1a(KOMP)Wtsi
testis, HOM, Male, WTSI
Eps15tm1a(KOMP)Wtsi
heart, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
blood vessel, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
skin, pinna, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
skin, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
lung, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
trachea, HOM, Male, WTSI
Eps15tm1a(KOMP)Wtsi
eye, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
skin, pinna, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
adrenal gland, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
prostate gland, HOM, Male, WTSI
Eps15tm1a(KOMP)Wtsi
kidney, HOM, Female, WTSI
No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images
Eps15tm1a(KOMP)Wtsi
body, HOM, Male, WTSI
Eps15tm1a(KOMP)Wtsi
body, HOM, Male, WTSI
Eps15tm1a(KOMP)Wtsi
head, HOM, Male, WTSI
Eps15tm1a(KOMP)Wtsi
body, HOM, Male, WTSI
Eps15tm1a(KOMP)Wtsi
head, HOM, Male, WTSI

View all 68 images

Eps15tm1a(KOMP)Wtsi
back skin, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
back skin, HOM, Female, WTSI
Eps15tm1a(KOMP)Wtsi
back skin, HOM, Female, WTSI

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Eps15tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Eps15tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Eps15tm357289(L1L2_Bact_P) Targeting vectors

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