Genes Phenotypes

Gene: Cdkn1a

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Name
cyclin-dependent kinase inhibitor 1A (P21)
MGI ID
MGI:104556
Synonyms
P21 p21 p21WAF CDKI mda6 Waf1 p21Cip1 CAP20 CIP1 SDI1 Cdkn1
Viability
Homozygous - Viable
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (13) Measurements chart (195) All data table (613)
Expression & images (73) Disease models (0) Order (5)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal spleen morphology Cdkn1atm1.1(KOMP)Vlcg HOM postnatal 0.00
small seminal vesicle Cdkn1atm1.1(KOMP)Vlcg HOM postnatal 0.00
abnormal epididymis morphology Cdkn1atm1.1(KOMP)Vlcg HOM postnatal 0.00
abnormal lung morphology Cdkn1atm1.1(KOMP)Vlcg HOM postnatal 0.00
enlarged epididymis Cdkn1atm1.1(KOMP)Vlcg HOM postnatal 0.00
decreased circulating insulin level Cdkn1atm1.1(KOMP)Vlcg HOM postnatal 8.61×10-06
abnormal seminal vesicle morphology Cdkn1atm1.1(KOMP)Vlcg HOM postnatal 0.00
enlarged spleen Cdkn1atm1.1(KOMP)Vlcg HOM postnatal 0.00
abnormal heart morphology Cdkn1atm1.1(KOMP)Vlcg HOM postnatal 0.00
enlarged heart Cdkn1atm1.1(KOMP)Vlcg HOM postnatal 0.00
abnormal testis morphology Cdkn1atm1.1(KOMP)Vlcg HOM postnatal 0.00
enlarged heart atrium Cdkn1atm1.1(KOMP)Vlcg HOM postnatal 0.00
small testis Cdkn1atm1.1(KOMP)Vlcg HOM postnatal 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Blood 2 No  (2/2) N/A
Bone marrow 2 No  (2/2) N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/383)  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2) N/A
Diaphragm 2 No  (2/2) N/A
Duodenum 2 No  (2/127)  (2/2) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No  (2/2) N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No  (2/2) N/A
Harderian gland 2 No  (2/2) N/A
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127)  (2/2) N/A
Jejunum 2 No  (6/127)  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No  (1/2) N/A
Mesenteric adipose tissue 2 No  (2/2) N/A
Mesenteric lymph node 2 No  (2/2) N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Parathyroid gland 2 No  (2/2) N/A
Parotid gland 2 No  (2/2) N/A
Penis 2 No  (1/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2) N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Quadriceps 2 No  (2/2) N/A
Sciatic nerve 2 No  (2/2) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Tongue 2 No  (5/127)  (2/2) N/A
Trachea 2 No  (1/2) N/A
Trigeminal V nerve 2 No  (2/2) N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vagina 2 No  (1/2) N/A
Vas deferens 2 No  (15/388)  (1/2) N/A
Vascular system 2 No N/A
Vesicular gland 2 No  (1/2) N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Dorso Ventral
40 Images
X-ray: XRay Images Lateral Orientation
20 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Cdkn1atm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Cdkn1atm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Cdkn1atm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Cdkn1aem1(IMPC)Cnrm Conditional Ready Mice
Cdkn1aem2(IMPC)Cnrm Exdel Mice