Ercc5 - excision repair cross-complementing rodent repair deficiency, complementation group 5 | International Mouse Phenotyping Consortium

Phenotype	Allele	Zyg	Life Stage
embryonic growth retardation	Ercc5^{tm2b(EUCOMM)Hmgu}	HOM	embryonic day 18.5
abnormal embryo size	Ercc5^{tm2b(EUCOMM)Hmgu}	HOM	embryonic day 18.5
preweaning lethality, complete penetrance	Ercc5^{tm2b(EUCOMM)Hmgu}	HOM	n/a

Table Images

Expression No Expression Ambiguous No Tissue Available

Anatomy	#HET Specimens	HOM Images?	WT Expr	Mutant Expr	Images
Adrenal gland	2	No	(2/584)		N/A
Aorta	2	No			N/A
Bone	2	No			N/A
Brain	2	No			N/A
Brainstem	2	No			N/A
Brown adipose tissue	2	No			N/A
Cartilage tissue	2	No			N/A
Cecum	2	No	(12/383)		N/A
Cerebellum	2	No			N/A
Cerebral cortex	2	No			N/A
Esophagus	2	No	(7/415)		N/A
Eye	2	No			N/A
Gall bladder	2	No			N/A
Heart	2	No			N/A
Hippocampus	2	No			N/A
Hypothalamus	2	No			N/A
Kidney	2	No	(18/584)	(2/2)	N/A
Large intestine	2	No	(10/584)		N/A
Liver	2	No			N/A
Lower urinary tract	2	No			N/A
Lung	2	No			N/A
Lymph node	2	No			N/A
Mammary gland	2	No			N/A
Mesenteric lymph node	2	No			N/A
Olfactory lobe	2	No			N/A
Oral epithelium	2	No			N/A
Ovary	2	No	(1/584)		N/A
Oviduct	2	No			N/A
Pancreas	2	No	(5/584)		N/A
Parathyroid gland	2	No			N/A
Peripheral nervous system	2	No			N/A
Peyer's patch	2	No			N/A
Pituitary gland	2	No			N/A
Prostate gland	2	No	(12/584)		N/A
Skeletal muscle	2	No			N/A
Skin	2	No			N/A
Small intestine	2	No	(9/584)		N/A
Spinal cord	2	No			N/A
Spleen	2	No	(2/584)		N/A
Stomach	2	No	(12/584)		N/A
Striatum	2	No			N/A
Testis	2	No	(2/584)	(1/2)	N/A
Thymus	2	No			N/A
Thyroid gland	2	No	(15/584)		N/A
Trachea	2	No			N/A
Trigeminal V nerve	2	No			N/A
Urinary bladder	2	No			N/A
Uterus	2	No			N/A
Vas deferens	2	No	(15/388)		N/A
Vascular system	2	No			N/A
White adipose tissue	2	No			N/A

Table Images

Expression No Expression Ambiguous No Tissue Available

Anatomy	#HET Specimens	WT Expr	Images
Heart atrium	2	(1/47)	N/A
Axial skeleton	2	(1/51)	N/A
Brain	2	(6/485)	N/A
Central nervous system ganglion	2	(1/51)	N/A
Cranium	2	(1/46)	N/A
Dorsal root ganglion	2	(1/47)	N/A
Ear	2	(1/485)	N/A
Embryo	2	(1/485)	N/A
Outer ear	2	(1/47)	N/A
Eye	2	(1/485)	N/A
Femur pre-cartilage condensation	2	(1/46)	N/A
Foot	2	(1/485)	N/A
Forearm	2	(1/282)	N/A
Forebrain	2	(1/485)	N/A
Forelimb	2	(1/485)	N/A
Fronto-nasal process	2	(1/48)	N/A
Gut	2	(1/50)	N/A
Hand	2	(1/485)	N/A
Head	2	(5/485)	N/A
Head mesenchyme	2	(1/47)	N/A
Heart	2	(1/485)	N/A
Heart ventricle	2	(1/47)	N/A
Hindbrain	2	(6/485)	N/A
Hindlimb	2	(1/485)	N/A
Humerus pre-cartilage condensation	2	(1/46)	N/A
Inner ear	2	(1/46)	N/A
Intestine	2	(1/47)	N/A
Liver	2	(1/485)	N/A
Lower leg	2	(1/282)	N/A
Lung	2	(1/485)	N/A
Mandibular process	2	(1/485)	N/A
Maxillary process	2	(1/485)	N/A
Mesonephros of female	2	(1/46)	N/A
Mesonephros of male	2	(1/46)	N/A
Metanephros	2	(1/46)	N/A
Midbrain	2	(1/485)	N/A
Nasal septum	2	(1/47)	N/A
Nose	2	(1/51)	N/A
Notochord	2	(1/47)	N/A
Oral cavity	2	(1/485)	N/A
Outflow tract	2	(1/47)	N/A
Pancreas	2	(1/46)	N/A
Pericardium	2	(1/46)	N/A
Pharynx	2	(1/46)	N/A
Radius-ulna pre-cartilage condensation	2	(1/46)	N/A
Rib pre-cartilage condensation	2	(1/46)	N/A
Skeleton	2	(1/51)	N/A
Skin	2	(1/485)	N/A
Spinal cord	2	(1/50)	N/A
Stomach	2	(1/46)	N/A
Tail	2	(1/485)	N/A
Tail somite	2	(1/485)	N/A
Thoracic vertebral cartilage condensation	2	(1/46)	N/A
Tongue	2	(1/46)	N/A
Trachea	2	(1/50)	N/A
Trunk mesenchyme	2	(1/47)	N/A
Umbilical artery embryonic part	2	(1/47)	N/A
Umbilical vein embryonic part	2	(1/47)	N/A
Upper arm	2	(1/282)	N/A
Upper leg	2	(1/282)	N/A
Urinary system	2	(1/50)	N/A
Vibrissa	2	(1/47)	N/A

MGI Allele	Allele Type	Availability
Ercc5^{tm2a(EUCOMM)Hmgu}	KO first allele (reporter-tagged insertion with conditional potential)	Mice, Targeting vectors, ES Cells
Ercc5^{tm2b(EUCOMM)Hmgu}	Reporter-tagged deletion allele (post-Cre)	Mice, Tissue

Gene: Ercc5