Genes Phenotypes

Gene: Ercc5

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Name
excision repair cross-complementing rodent repair deficiency, complementation group 5
MGI ID
MGI:103582
Synonyms
Xpg
Viability
Homozygous - Lethal
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (8) Measurements chart (226) All data table (603)
Expression & images (113) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Ercc5tm2b(EUCOMM)Hmgu HOM Early adult 0.00
increased mean corpuscular hemoglobin concentration Ercc5tm2b(EUCOMM)Hmgu HET Early adult 1.60×10-10
decreased hematocrit Ercc5tm2b(EUCOMM)Hmgu HET Early adult 9.47×10-22
abnormal embryo size Ercc5tm2b(EUCOMM)Hmgu HOM E18.5 0.00
increased mean corpuscular hemoglobin Ercc5tm2b(EUCOMM)Hmgu HET Early adult 0.00
thrombocytosis Ercc5tm2b(EUCOMM)Hmgu HET Early adult 9.89×10-14
decreased erythrocyte cell number Ercc5tm2b(EUCOMM)Hmgu HET Early adult 4.19×10-19
embryonic growth retardation Ercc5tm2b(EUCOMM)Hmgu HOM E18.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/388) N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2  (1/57) N/A
Axial skeleton 2  (1/61)  (2/2) N/A
Brain 2  (6/504)  (2/2) N/A
Central nervous system ganglion 2  (1/70)  (2/2) N/A
Cranium 2  (1/61)  (2/2) N/A
Dorsal root ganglion 2  (1/57)  (2/2) N/A
Ear 2  (1/504)  (2/2) N/A
Embryo 2  (1/505)  (2/2) N/A
Outer ear 2  (1/66)  (2/2) N/A
Eye 2  (1/504)  (2/2) N/A
Femur pre-cartilage condensation 2  (1/52)  (2/2) N/A
Foot 2  (1/504)  (2/2) N/A
Forearm 2  (1/297)  (2/2) N/A
Forebrain 2  (1/504)  (2/2) N/A
Forelimb 2  (1/504)  (2/2) N/A
Fronto-nasal process 2  (1/58)  (2/2) N/A
Gut 2  (1/56) N/A
Hand 2  (1/503)  (2/2) N/A
Head 2  (5/504)  (2/2) N/A
Head mesenchyme 2  (1/57)  (2/2) N/A
Heart 2  (1/504)  (2/2) N/A
Heart ventricle 2  (1/57) N/A
Hindbrain 2  (6/504)  (2/2) N/A
Hindlimb 2  (1/503)  (2/2) N/A
Humerus pre-cartilage condensation 2  (1/61)  (2/2) N/A
Inner ear 2  (1/61) N/A
Intestine 2  (1/55) N/A
Liver 2  (1/504)  (2/2) N/A
Lower leg 2  (1/297)  (2/2) N/A
Lung 2  (1/500)  (2/2) N/A
Mandibular process 2  (1/504)  (2/2) N/A
Maxillary process 2  (1/504)  (2/2) N/A
Mesonephros of female 2  (1/52)  (1/2) N/A
Mesonephros of male 2  (1/52)  (1/2) N/A
Metanephros 2  (1/52)  (2/2) N/A
Midbrain 2  (1/504)  (2/2) N/A
Nasal septum 2  (1/57)  (2/2) N/A
Nose 2  (1/70)  (2/2) N/A
Notochord 2  (1/57)  (2/2) N/A
Oral cavity 2  (1/504)  (2/2) N/A
Outflow tract 2  (1/57) N/A
Pancreas 2  (1/52) N/A
Pericardium 2  (1/52) N/A
Pharynx 2  (1/52)  (2/2) N/A
Radius-ulna pre-cartilage condensation 2  (1/61)  (2/2) N/A
Rib pre-cartilage condensation 2  (1/54)  (2/2) N/A
Skeleton 2  (1/70)  (2/2) N/A
Skin 2  (1/504)  (2/2) N/A
Spinal cord 2  (1/69)  (2/2) N/A
Stomach 2  (1/52)  (2/2) N/A
Tail 2  (1/504)  (2/2) N/A
Tail somite 2  (1/504)  (2/2) N/A
Thoracic vertebral cartilage condensation 2  (1/52)  (2/2) N/A
Tongue 2  (1/52)  (2/2) N/A
Trachea 2  (1/56) N/A
Trunk mesenchyme 2  (1/57)  (2/2) N/A
Umbilical artery embryonic part 2  (1/57)  (2/2) N/A
Umbilical vein embryonic part 2  (1/57)  (2/2) N/A
Upper arm 2  (1/297)  (2/2) N/A
Upper leg 2  (1/297)  (2/2) N/A
Urinary system 2  (1/56)  (2/2) N/A
Vibrissa 2  (1/66)  (2/2) N/A

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ercc5tm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ercc5tm2b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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