Tiam1 | T cell lymphoma invasion and metastasis 1

GeneMGI:103306Synonyms: D16Ium10, D16Ium10e

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased cornea thickness1 supporting datasetTiam1tm1b(EUCOMM)HmguhomozygoteEarly adult9.96x10-5 
decreased exploration in new environment1 supporting datasetTiam1tm1b(EUCOMM)HmguhomozygoteEarly adult6.07x10-9 
decreased locomotor activity1 supporting datasetTiam1tm1b(EUCOMM)HmguhomozygoteEarly adult4.65x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tiam1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Tiam1tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Tiam1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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