Bmp7 | bone morphogenetic protein 7

GeneMGI:103302Synonyms: osteogenic protein 1, OP1

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Immune system Hematopoietic system

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased mean corpuscular volume1 supporting datasetBmp7tm1a(EUCOMM)HmguheterozygoteEarly adult5.4x10-5 
increased monocyte cell number1 supporting datasetBmp7tm1a(EUCOMM)HmguheterozygoteEarly adult1.12x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Bmp7tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Bmp7tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Bmp7tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Bmp7tm48315(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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