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Genes Phenotypes Help, News, Blog

Gene: Dnase1

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Name
deoxyribonuclease I
MGI ID
MGI:103157
Synonyms
DNaseI Dnl1
Viability
Data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (7) Measurements chart (174) All data table (371)
Expression & images (73) Disease models (0) Order (4)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
hydrometra Dnase1tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal urinary bladder morphology Dnase1tm1.1(KOMP)Vlcg HOM Early adult 0.00
decreased circulating insulin level Dnase1tm1.1(KOMP)Vlcg HOM Early adult 1.17×10-07
abnormal auditory brainstem response Dnase1tm1.1(KOMP)Vlcg HOM   Early adult 3.62×10-06
enlarged heart Dnase1tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal uterus morphology Dnase1tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal heart morphology Dnase1tm1.1(KOMP)Vlcg HOM Early adult 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No N/A
2 No  (4/583) N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (12/371) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No N/A
2 No  (12/127) N/A
2 No N/A
2 No  (2/127) N/A
2 No  (18/132)  Section images
2 No  (7/407) N/A
2 No N/A
2 No N/A
2 No N/A
2 No N/A
2 No  (2/583) N/A
2 No N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (14/127) N/A
2 No  (6/127)  (1/2)  Section images
2 No  (21/583)  (2/2)  Section images
2 No  (10/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No N/A
2 No N/A
2 No N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No  (5/583) N/A
2 No  (1/563) N/A
2 No N/A
2 No N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (12/583) N/A
2 No N/A
2 No N/A
2 No N/A
2 No  (1/583) N/A
2 No  (9/583) N/A
2 No  (3/583) N/A
2 No  (3/583) N/A
2 No  (13/583) N/A
2 No N/A
2 No  (3/583) N/A
2 No N/A
2 No  (2/130) N/A
2 No  (6/583) N/A
2 No  (1/583) N/A
2 No  (17/583) N/A
2 No  (5/127)  (1/2)  Section images
2 No  (3/583) N/A
2 No N/A
2 No N/A
2 No N/A
2 No N/A
2 No  (15/382)  Section images
2 No N/A
2 No N/A
2 No N/A
LacZ Wholemount Images
LacZ Section Images
Unassigned Top Level MA (1)
digestive system (2)
Jejunum expression
MA:0000340
postnatal mouse (9)
Epididymis tissue not available
MA:0000397
reproductive system (2)
Epididymis tissue not available
MA:0000397
respiratory system (1)
Tongue expression
MA:0000347
sensory organ (1)
Tongue expression
MA:0000347
trunk (8)
Epididymis tissue not available
MA:0000397
urinary system (5)
Kidney expression
MA:0000368
No Embryo expression data was found for this gene.

 Associated Images

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X-ray: XRay Images Whole Body Lateral Orientation
10 Images
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X-ray: XRay Images Whole Body Dorso Ventral
10 Images
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Adult LacZ: LacZ Images Section
10 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Dnase1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Dnase1tm214458(L1L2_Bact_P) Targeting vectors
Dnase1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Dnase1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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