Slc12a1 | solute carrier family 12, member 1

GeneMGI:103150Synonyms: urehr3, mBSC1, +2 more

Physiological systems

14 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Hematopoietic system

11 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:8Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased body weight3 supporting datasetsSlc12a1urehr3homozygoteEarly adult8.05x10-6 
increased blood urea nitrogen level1 supporting datasetSlc12a1urehr3homozygoteEarly adult8.41x10-33 
increased circulating creatinine level1 supporting datasetSlc12a1urehr3homozygoteEarly adult2.21x10-8 
increased circulating amylase level1 supporting datasetSlc12a1urehr3homozygoteEarly adult1.9x10-9 
decreased circulating chloride level1 supporting datasetSlc12a1urehr3homozygoteEarly adult1.43x10-11 
increased circulating calcium level1 supporting datasetSlc12a1urehr3homozygoteEarly adult1.4x10-7 
decreased hematocrit1 supporting datasetSlc12a1urehr3homozygoteEarly adult9.19x10-5 
decreased hemoglobin content1 supporting datasetSlc12a1urehr3homozygoteEarly adult4.36x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Slc12a1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter