Gene: Uchl1

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Name
ubiquitin carboxy-terminal hydrolase L1
MGI ID
MGI:103149
Synonyms
PGP9.5 PGP 9.5
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased large unstained cell number Uchl1tm1b(EUCOMM)Hmgu HET Early adult 7.53×10-05
hyperactivity Uchl1tm1b(EUCOMM)Hmgu HET   Early adult 3.12×10-06
increased prepulse inhibition Uchl1tm1b(EUCOMM)Hmgu HET Early adult 1.03×10-05
abnormal spine curvature Uchl1tm1b(EUCOMM)Hmgu HET Early adult 2.27×10-08
decreased circulating serum albumin level Uchl1tm1b(EUCOMM)Hmgu HET Early adult 9.90×10-05
increased circulating alkaline phosphatase level Uchl1tm1b(EUCOMM)Hmgu HET Early adult 1.90×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (2/2)  Wholemount images
Aorta 2 No  (1/583) N/A
Bone 2 No N/A
Brain 2 No  (4/583)  (2/2)  Wholemount images
Brainstem 2 No  (2/583)  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583) N/A
Cerebellum 2 No  (3/583)  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/583)  (2/2)  Wholemount images
Esophagus 2 No  (7/407)  (2/2)  Wholemount images
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No N/A
Heart 2 No  (2/583) N/A
Hippocampus 2 No  (3/583)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/583)  (2/2)  Wholemount images
Kidney 2 No  (21/583)  (2/2)  Wholemount images
Large intestine 2 No  (10/583)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (1/583)  (2/2)  Wholemount images
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/583)  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/583)  (1/2)  Wholemount images
Oviduct 2 No N/A
Pancreas 2 No  (5/583) N/A
Parathyroid gland 2 No  (1/563) N/A
Peripheral nervous system 2 No  (2/583)  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583)  (2/2)  Wholemount images
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583) N/A
Small intestine 2 No  (9/583)  (2/2)  Wholemount images
Spinal cord 2 No  (3/583)  (2/2)  Wholemount images
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583)  (2/2)  Wholemount images
Striatum 2 No  (3/583)  (2/2)  Wholemount images
Testis 2 No  (6/583)  (1/2)  Wholemount images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505)  (4/4) N/A
2  (1/505)  (2/4) N/A
2  (1/506)  (4/4) N/A
2  (1/505)  (4/4) N/A
2  (1/505) N/A
2  (1/505)  (4/4) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (5/505)  (4/4) N/A
2  (1/505)  (1/4) N/A
2  (6/505)  (4/4) N/A
2  (1/505) N/A
2  (1/503) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/505)  (1/4) N/A
2  (1/505)  (4/4) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/505)  (3/4) N/A
2  (1/505) N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
Adult LacZ: LacZ Images Wholemount
14 Images
Echo: M-Mode Images
32 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
6 Images

 Disease Models

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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Uchl1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Uchl1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells