Gene: Uchl1

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Name
ubiquitin carboxy-terminal hydrolase L1
MGI ID
MGI:103149
Synonyms
PGP9.5 PGP 9.5
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
hyperactivity Uchl1tm1b(EUCOMM)Hmgu HET Early adult 5.05×10-06
increased prepulse inhibition Uchl1tm1b(EUCOMM)Hmgu HET Early adult 1.20×10-05
decreased circulating fructosamine level Uchl1tm1b(EUCOMM)Hmgu HET Late adult 1.72×10-05
abnormal behavior Uchl1tm1b(EUCOMM)Hmgu HET Late adult 7.09×10-06
abnormal spine curvature Uchl1tm1b(EUCOMM)Hmgu HET Early adult 2.66×10-08
abnormal behavior Uchl1tm1b(EUCOMM)Hmgu HET Early adult 1.03×10-06
decreased circulating cholesterol level Uchl1tm1b(EUCOMM)Hmgu HET Late adult 2.33×10-05
hyperactivity Uchl1tm1b(EUCOMM)Hmgu HET Late adult 9.41×10-05
increased circulating chloride level Uchl1tm1b(EUCOMM)Hmgu HET Late adult 4.71×10-07
decreased circulating total protein level Uchl1tm1b(EUCOMM)Hmgu HET Late adult 1.05×10-06
decreased circulating serum albumin level Uchl1tm1b(EUCOMM)Hmgu HET Late adult 3.68×10-06

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Viewing: all phenotypes
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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504)  (4/4) N/A
Ear 2  (1/504)  (2/4) N/A
Embryo 2  (1/505)  (4/4) N/A
Eye 2  (1/504)  (4/4) N/A
Foot 2  (1/504) N/A
Forebrain 2  (1/504)  (4/4) N/A
Forelimb 2  (1/504) N/A
Hand 2  (1/503) N/A
Head 2  (5/504)  (4/4) N/A
Heart 2  (1/504)  (1/4) N/A
Hindbrain 2  (6/504)  (4/4) N/A
Hindlimb 2  (1/503) N/A
Liver 2  (1/504) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504) N/A
Maxillary process 2  (1/504)  (1/4) N/A
Midbrain 2  (1/504)  (4/4) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/504) N/A
Tail 2  (1/504)  (3/4) N/A
Tail somite 2  (1/504) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
14 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
6 Images
Echo: M-Mode Images
32 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Produced
Uchl1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Uchl1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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