Genes Phenotypes

Gene: Uchl1

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Name
ubiquitin carboxy-terminal hydrolase L1
MGI ID
MGI:103149
Synonyms
PGP9.5 PGP 9.5
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (11) Measurements chart (292) All data table (796)
Expression & images (67) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
hyperactivity Uchl1tm1b(EUCOMM)Hmgu HET Early adult 5.05×10-06
increased prepulse inhibition Uchl1tm1b(EUCOMM)Hmgu HET Early adult 1.20×10-05
decreased circulating fructosamine level Uchl1tm1b(EUCOMM)Hmgu HET Late adult 1.72×10-05
abnormal behavior Uchl1tm1b(EUCOMM)Hmgu HET Late adult 7.09×10-06
abnormal spine curvature Uchl1tm1b(EUCOMM)Hmgu HET Early adult 2.66×10-08
abnormal behavior Uchl1tm1b(EUCOMM)Hmgu HET Early adult 1.03×10-06
decreased circulating cholesterol level Uchl1tm1b(EUCOMM)Hmgu HET Late adult 2.33×10-05
hyperactivity Uchl1tm1b(EUCOMM)Hmgu HET Late adult 9.41×10-05
increased circulating chloride level Uchl1tm1b(EUCOMM)Hmgu HET Late adult 4.71×10-07
decreased circulating total protein level Uchl1tm1b(EUCOMM)Hmgu HET Late adult 1.05×10-06
decreased circulating serum albumin level Uchl1tm1b(EUCOMM)Hmgu HET Late adult 3.68×10-06

Download data as:  TSV  XLS

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
digestive system (3)
Large Intestine expression
MA:0000333
endocrine system (1)
Adrenal gland expression
MA:0000116
nervous system (5)
Cerebral Cortex expression
Striatum expression
Hippocampus expression
Brain expression
MA:0000185
MA:0000891
MA:0000191
MA:0000168
postnatal mouse (14)
Adrenal gland expression
MA:0000116
reproductive system (2)
Ovary expression
MA:0000384
sensory organ (1)
Eye expression
MA:0000261
trunk (8)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504)  (4/4) N/A
Ear 2  (1/504)  (2/4) N/A
Embryo 2  (1/505)  (4/4) N/A
Eye 2  (1/504)  (4/4) N/A
Foot 2  (1/504) N/A
Forebrain 2  (1/504)  (4/4) N/A
Forelimb 2  (1/504) N/A
Hand 2  (1/503) N/A
Head 2  (5/504)  (4/4) N/A
Heart 2  (1/504)  (1/4) N/A
Hindbrain 2  (6/504)  (4/4) N/A
Hindlimb 2  (1/503) N/A
Liver 2  (1/504) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504) N/A
Maxillary process 2  (1/504)  (1/4) N/A
Midbrain 2  (1/504)  (4/4) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/504) N/A
Tail 2  (1/504)  (3/4) N/A
Tail somite 2  (1/504) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
14 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
6 Images
Echo: M-Mode Images
32 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Produced
Uchl1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Uchl1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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