Gene: Ube2b

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Name
ubiquitin-conjugating enzyme E2B
MGI ID
MGI:102944
Synonyms
E2-14k HR6B Rad6b
Viability
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased grip strength Ube2btm1a(EUCOMM)Wtsi HET Early adult 8.03×10-05
preweaning lethality, incomplete penetrance Ube2btm1b(EUCOMM)Wtsi HOM   Early adult 0.00
increased circulating alkaline phosphatase level Ube2btm1a(EUCOMM)Wtsi HET   Early adult 5.33×10-05
abnormal behavior Ube2btm1a(EUCOMM)Wtsi HET Early adult 1.38×10-06
enlarged heart Ube2btm1b(EUCOMM)Wtsi HET Early adult 0.00
abnormal coat appearance Ube2btm1b(EUCOMM)Wtsi HET Early adult 7.79×10-06
abnormal gait Ube2btm1b(EUCOMM)Wtsi HET Early adult 6.75×10-07
limb grasping Ube2btm1b(EUCOMM)Wtsi HET Early adult 1.12×10-06

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Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583)  (2/2)  Wholemount images
2 No  (1/583)  (2/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No  (4/583)  (2/2)  Wholemount images
2 No  (2/583)  (2/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No  (1/583)  (2/2)  Wholemount images
2 No  (3/583)  (2/2)  Wholemount images
2 No  (2/583)  (2/2)  Wholemount images
2 No  (7/407)  (2/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No  (2/583)  (2/2)  Wholemount images
2 No  (3/583)  (2/2)  Wholemount images
2 No  (2/583)  (2/2)  Wholemount images
2 No  (21/583)  (2/2)  Wholemount images
2 No  (10/583)  (2/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No  (1/583)  (2/2)  Wholemount images
2 No  (2/583)  (2/2)  Wholemount images
2 No  (1/583)  (2/2)  Wholemount images
2 No  (1/2)  Wholemount images
2 No  (2/583)  (2/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No  (1/583)  (1/2)  Wholemount images
2 No  (1/2)  Wholemount images
2 No  (5/583)  (2/2)  Wholemount images
2 No  (1/563)  (2/2)  Wholemount images
2 No  (2/583)  (2/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No  (1/583)  (2/2)  Wholemount images
2 No  (12/583)  (1/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No  (1/583)  (2/2)  Wholemount images
2 No  (9/583)  (2/2)  Wholemount images
2 No  (3/583)  (2/2)  Wholemount images
2 No  (3/583)  (2/2)  Wholemount images
2 No  (13/583)  (2/2)  Wholemount images
2 No  (3/583)  (2/2)  Wholemount images
2 No  (6/583)  (1/2)  Wholemount images
2 No  (1/583)  (2/2)  Wholemount images
2 No  (17/583)  (2/2)  Wholemount images
2 No  (3/583)  (2/2)  Wholemount images
2 No  (1/2)  Wholemount images
2 No  (2/2)  Wholemount images
2 No  (2/2)  Wholemount images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505)  (4/4) N/A
2  (1/505)  (2/4) N/A
2  (1/506)  (4/4) N/A
2  (1/505)  (4/4) N/A
2  (1/505)  (3/4) N/A
2  (1/505)  (4/4) N/A
2  (1/505)  (4/4) N/A
2  (1/505)  (3/4) N/A
2  (5/505)  (4/4) N/A
2  (1/505)  (2/4) N/A
2  (6/505)  (4/4) N/A
2  (1/505)  (4/4) N/A
2  (1/503)  (2/4) N/A
2  (1/503)  (2/4) N/A
2  (1/505)  (2/4) N/A
2  (1/505)  (2/4) N/A
2  (1/505)  (4/4) N/A
2  (1/503)  (2/4) N/A
2  (1/505)  (2/4) N/A
2  (1/505)  (4/4) N/A
2  (1/505)  (4/4) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
28 Images
X-ray: XRay Images Whole Body Dorso Ventral
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
Echo: M-Mode Images
32 Images
X-ray: XRay Images Whole Body Lateral Orientation
12 Images
Embryo LacZ: LacZ images wholemount
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ube2btm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ube2btm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Ube2btm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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