Mybpc3 | myosin binding protein C, cardiac
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Behavior/neurological Cardiovascular system
16 No significant impact
4 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
increased heart weight | 1 supporting dataset | Mybpc3tm1a(EUCOMM)Hmgu | homozygote | Early adult | 4.78x10-27 | ||
abnormal heart morphology | 1 supporting dataset | Mybpc3tm1a(EUCOMM)Hmgu | homozygote | Early adult | 1.08x10-5 | ||
increased circulating potassium level | 1 supporting dataset | Mybpc3tm1a(EUCOMM)Hmgu | homozygote | Early adult | 3.43x10-5 | ||
abnormal response to new environment | 1 supporting dataset | Mybpc3tm1a(EUCOMM)Hmgu | homozygote | Early adult | 6.9x10-5 | ||
decreased circulating amylase level | 1 supporting dataset | Mybpc3tm1a(EUCOMM)Hmgu | homozygote | Early adult | 1.4x10-5 |
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External links
No external links available for Mybpc3.
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Mybpc3tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Mybpc3tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Mybpc3tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |