Gene: Acvr2a

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal craniofacial morphology Acvr2atm1.1(KOMP)Vlcg HOM E15.5 0.00
decreased neutrophil cell number Acvr2atm1.1(KOMP)Vlcg HET Early adult 1.04×10-06
decreased eosinophil cell number Acvr2atm1.1(KOMP)Vlcg HET Early adult 1.93×10-05
abnormal behavior Acvr2atm1.1(KOMP)Vlcg HET Early adult 9.86×10-05
abnormal eosinophil cell number Acvr2atm1.1(KOMP)Vlcg HET Early adult 7.45×10-08
abnormal embryo size Acvr2atm1.1(KOMP)Vlcg HET E12.5 0.00
abnormal anxiety-related response Acvr2atm1.1(KOMP)Vlcg HET Early adult 9.86×10-05
preweaning lethality, incomplete penetrance Acvr2atm1.1(KOMP)Vlcg HOM Early adult 0.00459
abnormal liver size Acvr2atm1.1(KOMP)Vlcg HET E12.5 0.00
abnormal eye morphology Acvr2atm1.1(KOMP)Vlcg HET E12.5 0.00
abnormal pericardium morphology Acvr2atm1.1(KOMP)Vlcg HET E12.5 0.00
abnormal embryo size Acvr2atm1.1(KOMP)Vlcg HOM E15.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/589) N/A
Aorta 2 No  (1/589)  (2/2)  Section images
Brain 2 No  (3/589)  (2/2)  Section images
Brainstem 2 No  (2/589)  (2/2) N/A
Brown adipose tissue 1 No  (1/1)  Section images
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/589)  (2/2) N/A
Cerebral cortex 2 No  (2/589)  (2/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No  (2/2)  Section images
Heart 2 No  (1/589)  (2/2) N/A
Hippocampus 2 No  (3/589) N/A
Hypothalamus 2 No  (2/589) N/A
Kidney 2 No  (20/589)  (2/2) N/A
Large intestine 2 No  (10/589)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/589) N/A
Lung 2 No  (1/589)  (2/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/589) N/A
Ovary 2 No  (1/589)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/589) N/A
Peripheral nervous system 2 No  (1/589) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/589) N/A
Prostate gland 2 No  (12/589)  (1/2) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/589)  (2/2) N/A
Spinal cord 2 No  (2/589)  (2/2)  Section images
Spleen 2 No  (2/589) N/A
Stomach 2 No  (13/589)  (2/2) N/A
Striatum 2 No  (3/589) N/A
Testis 2 No  (5/589) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (16/589) N/A
Trachea 2 No  (2/589) N/A
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2) N/A
Vascular system 2 No N/A
White adipose tissue 2 No  (1/2) N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/65)  (2/2) N/A
Brain 4  (6/506)  (2/4) N/A
Central nervous system ganglion 2  (1/74)  (2/2) N/A
Ear 4  (1/506)  (2/4) N/A
Embryo 4  (1/507)  (2/4) N/A
Eye 4  (1/506)  (2/4) N/A
Foot 4  (1/506)  (2/4) N/A
Forebrain 4  (1/506)  (2/4) N/A
Forelimb 4  (1/506)  (2/4) N/A
Gut 2  (1/60)  (2/2) N/A
Hand 4  (1/505)  (2/4) N/A
Head 4  (5/506)  (2/4) N/A
Heart 4  (1/506)  (2/4) N/A
Hindbrain 4  (6/506)  (2/4) N/A
Hindlimb 4  (1/505)  (2/4) N/A
Liver 4  (1/506)  (2/4) N/A
Lung 4  (1/502)  (2/4) N/A
Mandibular process 4  (1/506)  (2/4) N/A
Maxillary process 4  (1/506)  (2/4) N/A
Midbrain 4  (1/506)  (2/4) N/A
Nose 2  (1/74)  (2/2) N/A
Oral cavity 4  (1/506)  (2/4) N/A
Skeleton 2  (1/74)  (2/2) N/A
Skin 4  (1/506)  (2/4) N/A
Spinal cord 2  (1/73)  (2/2) N/A
Tail 4  (1/506)  (2/4) N/A
Tail somite 4  (1/506)  (2/4) N/A
Trachea 2  (1/60)  (2/2) N/A
Urinary system 2  (1/60)  (2/2) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
40 Images
Adult LacZ: LacZ Images Section
18 Images
Gross Morphology Embryo E14.5-E15.5
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
X-ray: XRay Images Whole Body Dorso Ventral
14 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Whole Body Lateral Orientation
14 Images
Gross Pathology and Tissue Collection
12 Images
Eye Morphology: Images Slit Lamp
7 Images
Eye Morphology: Images Ophthalmoscopy
2 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Acvr2atm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Acvr2atm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Acvr2atm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Acvr2atm270449(L1L2_Bact_P) Targeting vectors
Acvr2atm378905(L1L2_Bact_P) Targeting vectors

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