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Gene: Acvr2a

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Name
activin receptor IIA
MGI ID
MGI:102806
Synonyms
ActRIIa tActRII Acvr2
Viability
Data available
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (9) Measurements chart (196) All data table (908)
Expression & images (72) Disease models (0) Order (5)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal behavior Acvr2atm1.1(KOMP)Vlcg HET Early adult 9.86×10-05
abnormal embryo size Acvr2atm1.1(KOMP)Vlcg HOM E15.5 0.00
anophthalmia Acvr2atm1.1(KOMP)Vlcg HOM E15.5 0.00
increased thigmotaxis Acvr2atm1.1(KOMP)Vlcg HET Early adult 9.86×10-05
decreased eosinophil cell number Acvr2atm1.1(KOMP)Vlcg HET Early adult 1.93×10-05
microphthalmia Acvr2atm1.1(KOMP)Vlcg HOM E15.5 0.00
decreased neutrophil cell number Acvr2atm1.1(KOMP)Vlcg HET Early adult 1.04×10-06
abnormal craniofacial morphology Acvr2atm1.1(KOMP)Vlcg HOM E15.5 0.00
preweaning lethality, incomplete penetrance Acvr2atm1.1(KOMP)Vlcg HOM   Early adult 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583) N/A
2 No  (1/583)  (2/2)  Section images
2 No  (4/583)  (2/2)  Section images
2 No  (2/583)  (2/2) N/A
1 No  (1/1)  Section images
2 No  (1/583) N/A
2 No  (3/583)  (2/2) N/A
2 No  (2/583)  (2/2) N/A
2 No  (7/407) N/A
2 No  (2/2)  Section images
2 No  (2/583)  (2/2) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (21/583)  (2/2) N/A
2 No  (10/583)  (2/2) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (2/583)  (2/2)  Section images
2 No  (1/583) N/A
2 No N/A
2 No  (2/583) N/A
2 No  (1/583)  (1/2) N/A
2 No  (1/2) N/A
2 No  (5/583) N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (12/583)  (1/2) N/A
2 No N/A
2 No  (1/583)  (2/2)  Section images
2 No  (9/583)  (2/2) N/A
2 No  (3/583)  (2/2)  Section images
2 No  (3/583) N/A
2 No  (13/583)  (2/2) N/A
2 No  (3/583) N/A
2 No  (6/583) N/A
2 No  (1/583) N/A
2 No  (17/583) N/A
2 No  (3/583) N/A
2 No  (2/2)  Section images
2 No  (1/2) N/A
2 No N/A
2 No  (1/2) N/A
LacZ Wholemount Images
LacZ Section Images
adipose tissue (2)
Brown adipose tissue expression
MA:0000057
cardiovascular system (2)
Aorta expression
MA:0000062
integumental system (2)
Skin expression
MA:0000151
nervous system (4)
Brain expression
MA:0000168
postnatal mouse (18)
Aorta expression
MA:0000062
respiratory system (2)
Lung expression
MA:0000415
sensory organ (3)
Eye expression
MA:0000261
set of connective tissues (2)
Brown adipose tissue expression
MA:0000057
trunk (10)
Aorta expression
MA:0000062
urinary system (3)
Urinary bladder expression
MA:0000380
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/64)  (2/2) N/A
4  (6/505)  (2/4) N/A
2  (1/73)  (2/2) N/A
4  (1/505)  (2/4) N/A
4  (1/506)  (2/4) N/A
4  (1/505)  (2/4) N/A
4  (1/505)  (2/4) N/A
4  (1/505)  (2/4) N/A
4  (1/505)  (2/4) N/A
2  (1/59)  (2/2) N/A
4  (1/505)  (2/4) N/A
4  (5/505)  (2/4) N/A
4  (1/505)  (2/4) N/A
4  (6/505)  (2/4) N/A
4  (1/505)  (2/4) N/A
4  (1/503)  (2/4) N/A
4  (1/503)  (2/4) N/A
4  (1/505)  (2/4) N/A
4  (1/505)  (2/4) N/A
4  (1/505)  (2/4) N/A
2  (1/75)  (2/2) N/A
4  (1/503)  (2/4) N/A
2  (1/75)  (2/2) N/A
4  (1/505)  (2/4) N/A
2  (1/72)  (2/2) N/A
4  (1/505)  (2/4) N/A
4  (1/505)  (2/4) N/A
2  (1/59)  (2/2) N/A
2  (1/59)  (2/2) N/A

 Associated Images

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Eye Morphology: Images Ophthalmoscopy
2 Images
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X-ray: XRay Images Whole Body Dorso Ventral
14 Images
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X-ray: XRay Images Skull Lateral Orientation
14 Images
thumbnail
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
thumbnail
Embryo LacZ: LacZ images wholemount
40 Images
thumbnail
Eye Morphology: Images Slit Lamp
7 Images
thumbnail
Adult LacZ: LacZ Images Section
18 Images
thumbnail
Gross Pathology and Tissue Collection
12 Images
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X-ray: XRay Images Whole Body Lateral Orientation
14 Images
thumbnail
Gross Morphology Embryo E14.5-E15.5
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Acvr2atm270449(L1L2_Bact_P) Targeting vectors
Acvr2atm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Acvr2atm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Acvr2atm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Acvr2atm378905(L1L2_Bact_P) Targeting vectors

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