Genes Phenotypes

Gene: Acvr2a

Name
activin receptor IIA
MGI ID
MGI:102806
Synonyms
ActRIIa Acvr2 tActRII
Viability
Homozygous - Subviable
View
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (6) Measurements chart (292) All data table (824)
Expression & images (72) Disease models (0) Order (5)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, incomplete penetrance Acvr2atm1.1(KOMP)Vlcg HOM n/a 0.00
abnormal craniofacial morphology Acvr2atm1.1(KOMP)Vlcg HOM embryonic day 15.5 0.00
abnormal embryo size Acvr2atm1.1(KOMP)Vlcg HOM embryonic day 15.5 0.00
abnormal bone structure Acvr2atm1.1(KOMP)Vlcg HET postnatal 6.10×10-05
microphthalmia Acvr2atm1.1(KOMP)Vlcg HOM embryonic day 15.5 0.00
anophthalmia Acvr2atm1.1(KOMP)Vlcg HOM embryonic day 15.5 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No  (2/2)  Section images
Brain 2 No  (2/2)  Section images
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 1 No  (1/1)  Section images
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No  (2/2)  Section images
Heart 2 No  (2/2) N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2)  Section images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No N/A
Testis 2 No  (2/584) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2) N/A
Vascular system 2 No N/A
White adipose tissue 2 No  (1/2) N/A
LacZ Wholemount Images
LacZ Section Images
adipose tissue (2)
Brown adipose tissue expression
MA:0000057
cardiovascular system (2)
Aorta expression
MA:0000062
integumental system (2)
Skin expression
MA:0000151
nervous system (4)
Brain expression
MA:0000168
postnatal mouse (18)
Aorta expression
MA:0000062
respiratory system (2)
Lung expression
MA:0000415
sensory organ (3)
Eye expression
MA:0000261
set of connective tissues (2)
Brown adipose tissue expression
MA:0000057
trunk (10)
Aorta expression
MA:0000062
urinary system (3)
Urinary bladder expression
MA:0000380
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51)  (2/2) N/A
Brain 4  (6/485)  (2/4) N/A
Central nervous system ganglion 2  (1/51)  (2/2) N/A
Ear 4  (1/485)  (2/4) N/A
Embryo 4  (1/485)  (2/4) N/A
Eye 4  (1/485)  (2/4) N/A
Foot 4  (1/485)  (2/4) N/A
Forebrain 4  (1/485)  (2/4) N/A
Forelimb 4  (1/485)  (2/4) N/A
Gut 2  (1/50)  (2/2) N/A
Hand 4  (1/485)  (2/4) N/A
Head 4  (5/485)  (2/4) N/A
Heart 4  (1/485)  (2/4) N/A
Hindbrain 4  (6/485)  (2/4) N/A
Hindlimb 4  (1/485)  (2/4) N/A
Liver 4  (1/485)  (2/4) N/A
Lung 4  (1/485)  (2/4) N/A
Mandibular process 4  (1/485)  (2/4) N/A
Maxillary process 4  (1/485)  (2/4) N/A
Midbrain 4  (1/485)  (2/4) N/A
Nose 2  (1/51)  (2/2) N/A
Oral cavity 4  (1/485)  (2/4) N/A
Skeleton 2  (1/51)  (2/2) N/A
Skin 4  (1/485)  (2/4) N/A
Spinal cord 2  (1/50)  (2/2) N/A
Tail 4  (1/485)  (2/4) N/A
Tail somite 4  (1/485)  (2/4) N/A
Trachea 2  (1/50)  (2/2) N/A
Urinary system 2  (1/50)  (2/2) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
Gross Pathology and Tissue Collection
12 Images
Adult LacZ: LacZ Images Section
18 Images
Embryo LacZ: LacZ images wholemount
8 Images
Eye Morphology: Images Slit Lamp
7 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Dorso Ventral
14 Images
Gross Morphology Embryo E14.5-E15.5
8 Images
Eye Morphology: Images Ophthalmoscopy
2 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Acvr2atm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Acvr2atm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Acvr2atm378905(L1L2_Bact_P) Targeting vectors
Acvr2atm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Acvr2atm270449(L1L2_Bact_P) Targeting vectors

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter