Tgfb1i1 | transforming growth factor beta 1 induced transcript 1

GeneMGI:102784Synonyms: hic-5, TSC-5, +1 more

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Homeostasis/metabolism

17 No significant impact

6 Not tested

Data collections

Viability data
Body weight measurements
Embryo imaging data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

improved glucose tolerance1 supporting datasetTgfb1i1tm1b(KOMP)WtsihomozygoteEarly adult8.5x10-5 
increased circulating cholesterol level1 supporting datasetTgfb1i1tm1b(KOMP)WtsihomozygoteEarly adult4.37x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tgfb1i1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Tgfb1i1tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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