Gbp2 | guanylate binding protein 2
GeneMGI:102772
Physiological systems
18 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Cardiovascular system
16 No significant impact
6 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:70Adult tissues
0Embryo tissues
prolonged RR interval | 1 supporting dataset | Gbp2tm1b(KOMP)Wtsi | homozygote | Early adult | 2.71x10-6 | ||
increased heart rate variability | 1 supporting dataset | Gbp2tm1b(KOMP)Wtsi | homozygote | Early adult | 6.52x10-5 | ||
increased fasting circulating glucose level | 1 supporting dataset | Gbp2tm1b(KOMP)Wtsi | homozygote | Early adult | 4.46x10-6 |
| | | | | | | | | |
adrenal gland | heterozygote | n/a | 0% (0/1) | 0.7% (4/570) |
aorta | heterozygote | n/a | 0% (0/1) | 0.19% (1/533) |
blood | heterozygote | n/a | 0% (0/1) | 0% (0/17) |
bone | heterozygote | n/a | 0% (0/1) | 0% (0/394) |
bone marrow | heterozygote | n/a | 0% (0/1) | 0% (0/22) |
brain | heterozygote | n/a | 0% (0/1) | 0.86% (5/579) |
brainstem | heterozygote | n/a | 0% (0/1) | 0.41% (2/490) |
brown adipose tissue | heterozygote | n/a | 0% (0/1) | 0% (0/588) |
cartilage tissue | heterozygote | n/a | 0% (0/1) | 0.22% (1/454) |
cecum | heterozygote | n/a | 0% (0/1) | 7.75% (22/284) |
External links
No external links available for Gbp2.
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Gbp2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Gbp2tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Gbp2tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |