Gene: Runx3

Name
runt related transcription factor 3
MGI ID
MGI:102672
Synonyms
AML2 Cbfa3
Viability
Homozygous - Lethal
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Runx3tm1b(KOMP)Wtsi HOM n/a 0.00
abnormal locomotor behavior Runx3tm1b(KOMP)Wtsi HET postnatal 3.24×10-10

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584)  (1/2)  Section images
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132)  (1/2)  Section images
Testis 2 No  (2/584)  (1/2)  Section images
Thalamus 2 No N/A
Thymus 2 No  (2/2)  Section images
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (2/3) N/A
Dorsal root ganglion 2  (1/47) Image Only N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/3) N/A
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485)  (2/3) N/A
Fronto-nasal process 2  (1/48) Image Only N/A
Hand 2  (1/485) N/A
Head 2  (5/485)  (2/3) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485)  (2/3) N/A
Hindlimb 2  (1/485)  (2/3) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) Image Only N/A
Mandibular process 2  (1/485)  (2/3) N/A
Maxillary process 2  (1/485)  (2/3) N/A
Midbrain 2  (1/485) N/A
Nose 2  (1/51)  (2/3) N/A
Oral cavity 2  (1/485) Image Only N/A
Skin 2  (1/485) N/A
Spinal cord 2  (1/50)  (2/3) N/A
Tail 2  (1/485)  (2/3) N/A
Tail somite 2  (1/485) N/A
Vibrissa 2  (1/47)  (2/2) N/A

 Associated Images

Original Image
Adult LacZ: LacZ Images Section
5 Images
Gross Morphology Embryo E18.5
2 Images
Sleep Wake: Wake state (bmp file)
9 Images
Electroretinography 2: Rod and cone PDF
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Runx3tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Runx3tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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