Gene: Ppp5c

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protein phosphatase 5, catalytic subunit
PP5 ANP receptor
Other links
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
vertebral fusion Ppp5ctm1a(EUCOMM)Wtsi HOM postnatal 1.23×10-05
increased CD8-positive, alpha-beta T cell number Ppp5ctm1a(EUCOMM)Wtsi HOM postnatal 9.49×10-05
decreased circulating triglyceride level Ppp5ctm1a(EUCOMM)Wtsi HOM postnatal 1.41×10-07
increased T cell number Ppp5ctm1a(EUCOMM)Wtsi HOM postnatal 3.04×10-17
increased total body fat amount Ppp5ctm1a(EUCOMM)Wtsi HOM postnatal 1.13×10-09
decreased body weight Ppp5ctm1a(EUCOMM)Wtsi HOM postnatal 4.75×10-09
increased lean body mass Ppp5ctm1a(EUCOMM)Wtsi HOM postnatal 1.59×10-08
abnormal rib morphology Ppp5ctm1a(EUCOMM)Wtsi HOM postnatal 3.31×10-08
abnormal bone structure Ppp5ctm1a(EUCOMM)Wtsi HOM postnatal 7.82×10-06
decreased body length Ppp5ctm1a(EUCOMM)Wtsi HOM postnatal 2.17×10-10
decreased circulating glucose level Ppp5ctm1a(EUCOMM)Wtsi HOM postnatal 5.47×10-06
abnormal coat/hair pigmentation Ppp5ctm1a(EUCOMM)Wtsi HOM postnatal 1.28×10-06

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Select physiological systems to view:
Viewing: all phenotypes


IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/2) N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (1/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/2) N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Esophagus 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (1/2) N/A
Parathyroid gland 2 No  (1/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (1/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (1/2) N/A
Trachea 2 No N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Phenotype associated images not available

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Ppp5ctm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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