Ppp5c | protein phosphatase 5, catalytic subunit
Physiological systems
21 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Pigmentation Integument Growth/size/body region Skeleton
16 No significant impact
3 Not tested
Data collections
Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
abnormal rib morphology | 2 supporting datasets | Ppp5ctm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.31x10-8 | ||
vertebral fusion | 1 supporting dataset | Ppp5ctm1a(EUCOMM)Wtsi | homozygote | Early adult | 6.98x10-6 | ||
increased thoracic vertebrae number | 1 supporting dataset | Ppp5ctm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.85x10-6 | ||
abnormal coat/hair pigmentation | 1 supporting dataset | Ppp5ctm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.28x10-6 | ||
increased lumbar vertebrae number | 2 supporting datasets | Ppp5ctm1a(EUCOMM)Wtsi | homozygote | Early adult | 5.18x10-6 | ||
decreased circulating triglyceride level | 1 supporting dataset | Ppp5ctm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.15x10-11 | ||
decreased body length | 1 supporting dataset | Ppp5ctm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.39x10-5 | ||
increased rib number | 2 supporting datasets | Ppp5ctm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.09x10-7 | ||
decreased circulating glucose level | 1 supporting dataset | Ppp5ctm1a(EUCOMM)Wtsi | homozygote | Early adult | 8.76x10-8 | ||
increased lean body mass | 1 supporting dataset | Ppp5ctm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.84x10-6 |
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External links
No external links available for Ppp5c.
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Ppp5ctm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Ppp5ctm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |