Tex2 | testis expressed gene 2

GeneMGI:102465Synonyms: Taz4, Def-5, +1 more

Physiological systems

17 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

9 No significant impact

7 Not tested

Gene metrics:18Significant phenotypes
0Associated diseases
Expression examined in:50Adult tissues
51Embryo tissues

Phenotypes

increased circulating alanine transaminase level1 supporting datasetTex2tm1.1(KOMP)VlcghomozygoteLate adult1.55x10-9 
iris synechia1 supporting datasetTex2tm1.1(KOMP)VlcghomozygoteLate adult3.21x10-7 
abnormal bone structure1 supporting datasetTex2tm1.1(KOMP)VlcghomozygoteEarly adult7.44x10-5 
decreased mean corpuscular hemoglobin concentration1 supporting datasetTex2tm1.1(KOMP)VlcgheterozygoteEarly adult5.57x10-6 
decreased heart rate1 supporting datasetTex2em1(IMPC)JhomozygoteEarly adult3.69x10-5 
decreased grip strength1 supporting datasetTex2em1(IMPC)JhomozygoteEarly adult6.11x10-5 
abnormal lens morphology1 supporting datasetTex2tm1.1(KOMP)VlcghomozygoteLate adult4.8x10-5 
decreased body length1 supporting datasetTex2tm1.1(KOMP)VlcghomozygoteLate adult2.63x10-7 
prolonged RR interval1 supporting datasetTex2em1(IMPC)JhomozygoteEarly adult9.56x10-5 
decreased circulating calcium level1 supporting datasetTex2tm1.1(KOMP)VlcgheterozygoteEarly adult1.83x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tex2em1(IMPC)JExon Deletionmouse
Tex2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
mouse
Tex2tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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