Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
tenascin C
Synonyms:
Hxb,  hexabrachion,  C130033P17Rik,  TN-C,  TN,  tenascin-C,  cytotactin

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Tnc mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Tnc by orthology or direct annotation.

Disease Similarity of
phenotypes
Matching phenotypes Source
Deafness, Autosomal Dominant 56
OMIM:615629

The table below shows human diseases predicted to be associated to Tnc by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Severe Primary Trimethylaminuria
Anxiety, Negative affectivity, Aggressive behavior, Emotional lability, Low self esteem, Depression ORPHA:468726
Intellectual Developmental Disorder, Autosomal Recessive 25
Anxiety OMIM:614346
Panic Disorder 1
Anxiety OMIM:167870
Familial Alzheimer-Like Prion Disease
Cognitive impairment, Anxiety, Deficit in phonologic short-term memory, Emotional lability, Depre... ORPHA:280397
Obsessive-Compulsive Disorder
Anxiety, Depression, Skin-picking OMIM:164230
Intellectual Developmental Disorder, X-Linked 63
Anxiety OMIM:300387
Geniospasm 1
Anxiety OMIM:190100
Developmental And Epileptic Encephalopathy 97
Stereotypical hand wringing, Inability to walk, Tremor OMIM:619561
Paragangliomas 6
Elevated circulating catecholamine level, Paraganglioma OMIM:618464
Chorea, Benign Hereditary
Anxiety OMIM:118700
Intellectual Developmental Disorder, X-Linked 109
Stereotypical body rocking, Hyperactivity, Poor coordination, Recurrent hand flapping OMIM:309548
Fraxe Intellectual Disability
Stereotypical body rocking, Clumsiness, Hyperactivity, Recurrent hand flapping ORPHA:100973
Pandas
Abnormal fear/anxiety-related behavior, Emotional lability, Irritability, Separation insecurity, ... ORPHA:66624
Primary Dystonia, Dyt13 Type
Action tremor, Motor stereotypy, Involuntary movements, Torticollis, Postural tremor ORPHA:98807
Neurodevelopmental Disorder With Hypotonia And Autistic Features With Or Without Hyperkinetic Movements
Stereotypical hand wringing, Inability to walk, Chorea OMIM:618760
Atypical Rett Syndrome
Pill-rolling tremor, Apraxia, Loss of ability to walk, Impaired pain sensation, Inability to walk... ORPHA:3095
Childhood Disintegrative Disorder
Progressive language deterioration, Anxiety, Dementia, Motor deterioration, Mental deterioration,... ORPHA:168782
Severe Intellectual Disability And Progressive Spastic Paraplegia
Progressive spastic paraplegia, Motor stereotypy, Spastic dysarthria, Spasticity, Babinski sign, ... ORPHA:280763
Autosomal Recessive Non-Syndromic Intellectual Disability
Hyperactivity, Spasticity, Chorea, Motor stereotypy ORPHA:88616
Foxg1 Syndrome
Choreoathetosis, Motor stereotypy, Stereotypical hand wringing, Inability to walk, Spasticity, Di... ORPHA:561854
Intellectual Developmental Disorder, Autosomal Recessive 73
Gait ataxia, Poor coordination, Recurrent hand flapping OMIM:619717
Behavioral Variant Of Frontotemporal Dementia
Motor stereotypy, Fasciculations, Upper motor neuron dysfunction, Gait disturbance, Abnormality o... ORPHA:275864
Autism Spectrum Disorder Due To Auts2 Deficiency
Repetitive compulsive behavior, Motor stereotypy, Hyperactivity, Cerebral palsy, Spasticity, Atte... ORPHA:352490
Cdkl5-Deficiency Disorder
Stereotypical hand wringing, Impaired pain sensation, Difficulty walking, Gait disturbance ORPHA:505652
Rett Syndrome
Motor stereotypy, Stereotypical hand wringing, Inability to walk, Bradykinesia, Limb apraxia, Inc... ORPHA:778
Severe Neurodevelopmental Disorder With Feeding Difficulties-Stereotypic Hand Movement-Bilateral Cataract
Stereotypical hand wringing, Spasticity ORPHA:500545
Neurodevelopmental Disorder With Language Impairment And Behavioral Abnormalities
Stereotypical hand wringing, Inability to walk, Gait ataxia, Spasticity, Chorea OMIM:618917
Severe Intellectual Disability-Progressive Postnatal Microcephaly-Midline Stereotypic Hand Movements Syndrome
Stereotypical hand wringing, Hyperkinetic movements ORPHA:397933
X-Linked Intellectual Disability-Short Stature-Overweight Syndrome
Motor stereotypy, Upper limb spasticity, Gait disturbance, Decreased response to growth hormone s... ORPHA:457240
Syngap1-Related Developmental And Epileptic Encephalopathy
Ataxia, Poor coordination, Recurrent hand flapping, Abnormality of pain sensation, Gait disturban... ORPHA:544254
Early-Onset Schizophrenia
Suicidal ideation, Cognitive impairment, Unhappy demeanor, Anxiety, Anhedonia, Impairment in pers... ORPHA:96369
Paragangliomas 1
Chemodectoma, Vocal cord paralysis, Glomus tympanicum paraganglioma, Glomus jugular tumor, Adrena... OMIM:168000
Paragangliomas 3
Chemodectoma, Vocal cord paralysis, Glomus jugular tumor, Adrenal pheochromocytoma, Extraadrenal ... OMIM:605373
Intellectual Developmental Disorder, Autosomal Recessive 38
Recurrent hand flapping, Hyperactivity, Unsteady gait OMIM:615516
Lamb-Shaffer Syndrome
Upper motor neuron dysfunction, Hyperactivity, Ataxia, Motor stereotypy ORPHA:530983
Juvenile Neuronal Ceroid Lipofuscinosis
Parkinsonism, Myoclonic spasms, Motor stereotypy, Loss of ability to walk, Poor motor coordinatio... ORPHA:79264
Christianson Syndrome
Gait ataxia, Truncal ataxia, Motor stereotypy ORPHA:85278
48,Xxyy Syndrome
Motor stereotypy, Ataxia, Type II diabetes mellitus, Attention deficit hyperactivity disorder, Hy... ORPHA:10
Early-Onset Epileptic Encephalopathy-Cortical Blindness-Intellectual Disability-Facial Dysmorphism Syndrome
Inability to walk, Myoclonus, Motor stereotypy ORPHA:411986
Intellectual Developmental Disorder, Autosomal Dominant 7
Incoordination, Stereotypical hand wringing, Hyperactivity, Ataxia, Gait disturbance OMIM:614104
Late Infantile Neuronal Ceroid Lipofuscinosis
Cortical myoclonus, Motor stereotypy, Hyperactivity, Inability to walk, Ataxia, Spasticity, Gait ... ORPHA:168491
Developmental And Epileptic Encephalopathy 26
Stereotypical hand wringing OMIM:616056
Narcolepsy 7
Cataplexy, Type II diabetes mellitus, Narcolepsy OMIM:614250
2Q23.1 Microdeletion Syndrome
Hyperactivity, Ataxia, Motor stereotypy ORPHA:228402
Neurodevelopmental Disorder With Or Without Autistic Features And/Or Structural Brain Abnormalities
Spasticity, Recurrent hand flapping OMIM:618859
Cerebellar Ataxia, Deafness, And Narcolepsy, Autosomal Dominant
Dementia, Depression, Memory impairment, Narcolepsy OMIM:604121
Cystinosis
Hypothyroidism, Abnormal pyramidal sign, Motor stereotypy, Gait disturbance, Nephrogenic diabetes... ORPHA:213
Intellectual Disability-Severe Speech Delay-Mild Dysmorphism Syndrome
Hypothyroidism, Repetitive compulsive behavior, Spasticity, Oromotor apraxia, Diabetes mellitus, ... ORPHA:391372
Disseminated Sclerosis With Narcolepsy
Cataplexy, Narcolepsy OMIM:223300
Angelman Syndrome Due To Maternal 15Q11Q13 Deletion
Hyperactivity, Ataxia, Recurrent hand flapping, Tongue thrusting, Myoclonus, Gait imbalance, Broa... ORPHA:98794
Inverted Duplicated Chromosome 15 Syndrome
Hyperactivity, Precocious puberty, Hypogonadism, Motor stereotypy ORPHA:3306
Progressive Supranuclear Palsy
Blepharospasm, Abnormal synaptic transmission, Bradykinesia, Unsteady gait, Rigidity, Falls, Tremor ORPHA:683
Symptomatic Form Of Fragile X Syndrome In Female Carriers
Hypothyroidism, Motor stereotypy, Hyperactivity, Hyperthyroidism, Recurrent hand flapping, Diabet... ORPHA:449291
Pure Autonomic Failure
Abnormality of circulating catecholamine level ORPHA:441
Neurodevelopmental Disorder With Impaired Language And Ataxia And With Or Without Seizures
Opisthotonus, Choreoathetosis, Inability to walk, Limb hypertonia, Ataxia, Recurrent hand flappin... OMIM:619580
Bilateral Generalized Polymicrogyria
Eyelid myoclonus, Spastic tetraplegia, Motor stereotypy, Paroxysmal dyskinesia, Spasticity ORPHA:208447
Fragile X Syndrome
Hyperactivity, Recurrent hand flapping OMIM:300624
Autosomal Dominant Non-Syndromic Intellectual Disability
Eyelid myoclonus, Spasticity, Chorea, Motor stereotypy ORPHA:178469
X-Linked Intellectual Disability, Cantagrel Type
Tetraparesis, Motor stereotypy ORPHA:85277
Hyperammonemia Due To N-Acetylglutamate Synthase Deficiency
Paraplegia, Ataxia, Motor stereotypy ORPHA:927
Angelman Syndrome Due To A Point Mutation
Ataxia, Recurrent hand flapping, Tongue thrusting, Gait imbalance, Broad-based gait ORPHA:411511
Aromatic L-Amino Acid Decarboxylase Deficiency
Choreoathetosis, Blepharospasm, Limb hypertonia, Athetosis, Tongue thrusting, Limb tremor, Exagge... OMIM:608643
Leber Congenital Amaurosis 2
Eye poking OMIM:204100
Developmental And Epileptic Encephalopathy 87
Hypertonia, Recurrent hand flapping OMIM:618916
Developmental And Speech Delay Due To Sox5 Deficiency
Attention deficit hyperactivity disorder, Motor stereotypy ORPHA:313892
Severe Intellectual Disability-Short Stature-Behavioral Abnormalities-Facial Dysmorphism Syndrome
Hyperactivity, Motor stereotypy ORPHA:391307
Neurodevelopmental Disorder With Hypotonia, Seizures, And Absent Language
Recurrent hand flapping OMIM:617268
Leber Congenital Amaurosis 1
Eye poking OMIM:204000
4Q21 Microdeletion Syndrome
Tremor, Motor stereotypy ORPHA:238750
Cntnap2-Related Developmental And Epileptic Encephalopathy
Stereotypical hand wringing, Hyperactivity, Lower limb spasticity, Ataxia, Cerebral palsy, Precoc... ORPHA:163681
Autosomal Dominant Nocturnal Frontal Lobe Epilepsy
Attention deficit hyperactivity disorder, Involuntary movements, Motor stereotypy ORPHA:98784
Smith-Magenis Syndrome
Hypothyroidism, Motor stereotypy, Impaired pain sensation, Precocious puberty, Gait disturbance, ... ORPHA:819
Intellectual Developmental Disorder, X-Linked, Syndromic, Lubs Type
Repetitive compulsive behavior, Inability to walk, Lower limb spasticity, Ataxia, Rigidity, Progr... OMIM:300260
Intellectual Developmental Disorder, X-Linked, Syndromic, Bain Type
Hypertonia, Ataxia, Recurrent hand flapping, Gait disturbance, Attention deficit hyperactivity di... OMIM:300986
Microphthalmia-Brain Atrophy Syndrome
Tongue thrusting, Spasticity ORPHA:77299
Proximal 16P11.2 Microdeletion Syndrome
Choreoathetosis, Motor stereotypy, Paroxysmal dyskinesia, Speech apraxia, Attention deficit hyper... ORPHA:261197
Early-Onset Epileptic Encephalopathy And Intellectual Disability Due To Grin2A Mutation
Stereotypical hand wringing, Myoclonus, Hypertonia ORPHA:289266
Narcolepsy 3
Cataplexy, Narcolepsy OMIM:609039
Narcolepsy 1
Cataplexy, Narcolepsy OMIM:161400
Distal Xq28 Microduplication Syndrome
Stereotypical body rocking, Hypothyroidism, Attention deficit hyperactivity disorder, Tip-toe gait ORPHA:293939
22Q11.2 Duplication Syndrome
Attention deficit hyperactivity disorder, Aplasia/Hypoplasia of the thymus, Motor stereotypy ORPHA:1727
Angelman Syndrome Due To Paternal Uniparental Disomy Of Chromosome 15
Tongue thrusting, Gait imbalance, Broad-based gait ORPHA:98795
3P25.3 Microdeletion Syndrome
Attention deficit hyperactivity disorder, Ataxia, Motor stereotypy ORPHA:435638
Marbach-Schaaf Neurodevelopmental Syndrome
Tremor, Speech apraxia, Recurrent hand flapping, Torticollis, Attention deficit hyperactivity dis... OMIM:619680
5Q14.3 Microdeletion Syndrome
Motor stereotypy ORPHA:228384
Angelman Syndrome
Precocious puberty in females, Hyperactivity, Inability to walk, Ataxia, Recurrent hand flapping,... ORPHA:72
Microcephaly-Corpus Callosum And Cerebellar Vermis Hypoplasia-Facial Dysmorphism-Intellectual Disability Syndrom
Diabetes mellitus, Motor stereotypy ORPHA:500159
Cortical Dysgenesis With Pontocerebellar Hypoplasia Due To Tubb3 Mutation
Spastic tetraplegia, Motor stereotypy, Inability to walk, Spasticity, Torticollis, Oculomotor apr... ORPHA:300570
Megalocornea-Intellectual Disability Syndrome
Hypothyroidism, Ataxia, Motor stereotypy ORPHA:2479
Alazami Syndrome
Stereotypical hand wringing, Motor stereotypy ORPHA:319671
Autosomal Dominant Cerebellar Ataxia-Deafness-Narcolepsy Syndrome
Resting tremor, Head tremor, Ataxia, Narcolepsy, Spasticity, Babinski sign ORPHA:314404
Transketolase Deficiency
Attention deficit hyperactivity disorder, Type I diabetes mellitus, Motor stereotypy ORPHA:488618
Intellectual Developmental Disorder, X-Linked 98
Central hypothyroidism, Stereotypical hand wringing, Hyperactivity, Lower limb spasticity, Ataxia... OMIM:300912
Optic Atrophy-Intellectual Disability Syndrome
Repetitive compulsive behavior, Spasticity, Attention deficit hyperactivity disorder ORPHA:401777
Early-Onset Progressive Diffuse Brain Atrophy-Microcephaly-Muscle Weakness-Optic Atrophy Syndrome
Motor stereotypy, Fasciculations, Cataplexy, Ataxia, Tetraplegia, Spasticity, Progressive spasticity ORPHA:496641
Infantile Hypotonia-Oculomotor Anomalies-Hyperkinetic Movements-Developmental Delay Syndrome
Hemiballismus, Repetitive compulsive behavior, Choreoathetosis, Motor stereotypy, Athetoid cerebr... ORPHA:522077
Dilated Cardiomyopathy With Ataxia
Hypothyroidism, Action tremor, Repetitive compulsive behavior, Lower limb spasticity, Ataxia ORPHA:66634
Micrognathia-Recurrent Infections-Behavioral Abnormalities-Mild Intellectual Disability Syndrome
Gait ataxia, Attention deficit hyperactivity disorder, Tremor, Motor stereotypy ORPHA:476126
Intellectual Disability-Autism-Speech Apraxia-Craniofacial Dysmorphism Syndrome
Speech apraxia, Motor stereotypy ORPHA:529965
Childhood Absence Epilepsy
Punding, Limb myoclonus, Attention deficit hyperactivity disorder ORPHA:64280
Bainbridge-Ropers Syndrome
Hypertonia, Inability to walk, Recurrent hand flapping ORPHA:352577
Intellectual Disability-Macrocephaly-Hypotonia-Behavioral Abnormalities Syndrome
Motor stereotypy, Ataxia, Unsteady gait ORPHA:457279
Hydroxykynureninuria
Hypertonia, Motor stereotypy ORPHA:79155
Microcephaly-Intellectual Disability-Sensorineural Hearing Loss-Epilepsy-Abnormal Muscle Tone Syndrome
Inability to walk, Limb hypertonia, Spasticity, Motor stereotypy ORPHA:457351
Macrocephaly-Developmental Delay Syndrome
Motor stereotypy ORPHA:397612
Kohlschutter-Tonz Syndrome-Like
Stereotypical hand wringing, Inability to walk, Lower limb spasticity, Ataxia, Spasticity, Upper ... OMIM:619229
2Q37 Microdeletion Syndrome
Attention deficit hyperactivity disorder, Motor stereotypy ORPHA:1001
Rett Syndrome, Congenital Variant
Apraxia, Athetosis, Tongue thrusting, Spasticity, Chorea OMIM:613454
Foxg1 Syndrome Due To 14Q12 Microdeletion
Motor stereotypy ORPHA:261144
Spastic Tetraplegia-Thin Corpus Callosum-Progressive Postnatal Microcephaly Syndrome
Myoclonic spasms, Motor stereotypy, Hyperactivity, Lower limb spasticity, Clonus, Hypertonia ORPHA:447997
Phelan-Mcdermid Syndrome
Tongue thrusting, Impaired pain sensation, Broad-based gait, Unsteady gait OMIM:606232
White-Sutton Syndrome
Incoordination, Hyperactivity, Motor stereotypy ORPHA:468678
7Q11.23 Microduplication Syndrome
Motor stereotypy, Hyperactivity, Dysmetria, Unsteady gait ORPHA:96121
African Trypanosomiasis
Abnormality of circulating cortisol level, Abnormality of the endocrine system, Somatic sensory d... ORPHA:3385
Skeletal Dysplasia-T-Cell Immunodeficiency-Developmental Delay Syndrome
Motor stereotypy, Inability to walk, Opisthotonus, Hypertonia ORPHA:508533
21Q22.11Q22.12 Microdeletion Syndrome
Tongue thrusting, Stereotypical body rocking, Hyperactivity ORPHA:261323
Niemann-Pick Disease Type C
Abnormal pyramidal sign, Frequent falls, Intention tremor, Cataplexy, Lower limb spasticity, Atax... ORPHA:646
Bainbridge-Ropers Syndrome
Recurrent hand flapping, Hypertonia, Inability to walk, Precocious puberty OMIM:615485
Wiedemann-Steiner Syndrome
Hyperactivity, Decreased response to growth hormone stimulation test, Motor stereotypy ORPHA:319182
Intellectual Disability Syndrome Due To A Dyrk1A Point Mutation
Posterior pituitary hypoplasia, Attention deficit hyperactivity disorder, Motor stereotypy, Gait ... ORPHA:464311
Frontotemporal Lobar Degeneration With Tdp43 Inclusions, Grn-Related
Apraxia, Repetitive compulsive behavior, Parkinsonism OMIM:607485
Dyrk1A-Related Intellectual Disability Syndrome
Motor stereotypy, Hyperactivity, Anterior pituitary hypoplasia, Gait disturbance ORPHA:464306
Prader-Willi Syndrome Due To Translocation
Hypogonadotropic hypogonadism, Anterior pituitary hypoplasia, Motor stereotypy, Decreased respons... ORPHA:177907
Intellectual Disability-Seizures-Abnormal Gait-Facial Dysmorphism Syndrome
Repetitive compulsive behavior, Pineal cyst, Motor stereotypy, Gait ataxia, Stereotypical body ro... ORPHA:513456
Nmda Receptor Encephalitis
Opisthotonus, Choreoathetosis, Motor stereotypy, Involuntary movements, Neoplasm of the thymus, R... ORPHA:217253
Microcephaly 26, Primary, Autosomal Dominant
Stereotypical hand wringing, Spastic tetraparesis OMIM:619179
Developmental Delay, Impaired Speech, And Behavioral Abnormalities
Repetitive compulsive behavior, Spastic tetraplegia, Intention tremor, Isometric tremor, Spastic ... OMIM:619475
Pyruvate Carboxylase Deficiency
Abnormal pyramidal sign, Ataxia, Recurrent hand flapping, Tip-toe gait, Tremor ORPHA:3008
Kleefstra Syndrome
Motor stereotypy ORPHA:261494
Microcephalic Cortical Malformations-Short Stature Due To Rttn Deficiency
Abnormal pyramidal sign, Motor stereotypy, Spasticity, Hyperkinetic movements, Hypertonia ORPHA:468631
Von Hippel-Lindau Disease
Paraganglioma, Pancreatic endocrine tumor, Adrenal pheochromocytoma, Elevated circulating catecho... ORPHA:892
Oculocerebrorenal Syndrome Of Lowe
Diabetes insipidus, Motor stereotypy, Abnormal calcium-phosphate regulating hormone level, Clonus... ORPHA:534
Intellectual Disability-Seizures-Macrocephaly-Obesity Syndrome
Abnormality of the pineal gland, Hemiparesis, Broad-based gait, Tongue thrusting ORPHA:369950
Dyrk1A-Related Intellectual Disability Syndrome Due To 21Q22.13Q22.2 Microdeletion
Hypothyroidism, Posterior pituitary hypoplasia, Stereotypical hand wringing, Ataxia, Gait disturb... ORPHA:268261
Cardiofaciocutaneous Syndrome 1
Tongue thrusting, Oculomotor apraxia, Hypertonia OMIM:115150
Tuberous Sclerosis Complex
Repetitive compulsive behavior, Hyperactivity, Parathyroid adenoma, Pancreatic endocrine tumor, P... ORPHA:805
Dpagt1-Cdg
Inability to walk, Tremor, Akinesia, Ataxia, Stereotypical body rocking, Hypertonia ORPHA:86309
Mgat2-Cdg
Stereotypical hand wringing, Abnormality of the endocrine system ORPHA:79329
Intellectual Disability-Cardiac Anomalies-Short Stature-Joint Laxity Syndrome
Motor stereotypy ORPHA:508498
Mucopolysaccharidosis Type 2
Hyperactivity, Motor stereotypy ORPHA:580
Pura-Related Severe Neonatal Hypotonia-Seizures-Encephalopathy Syndrome
Hypothyroidism, Abnormality of the anterior pituitary, Stereotypical hand wringing, Involuntary m... ORPHA:438213
1P36 Deletion Syndrome
Hypothyroidism, Motor stereotypy, Gait disturbance, Hemiplegia/hemiparesis, Hypogonadism ORPHA:1606
Norrie Disease
Motor stereotypy, Clonus, Diabetes mellitus, Attention deficit hyperactivity disorder, Delayed pu... ORPHA:649
Rubinstein-Taybi Syndrome Due To 16P13.3 Microdeletion
Hyperactivity, Motor stereotypy ORPHA:353281
Rubinstein-Taybi Syndrome Due To Ep300 Haploinsufficiency
Hyperactivity, Motor stereotypy ORPHA:353284
Rubinstein-Taybi Syndrome Due To Crebbp Mutations
Hyperactivity, Motor stereotypy ORPHA:353277
Neurodevelopmental Disorder With Hypotonia And Dysmorphic Facies
Small pituitary gland, Thyroid hypoplasia, Tip-toe gait, Stereotypical body rocking, Decreased re... OMIM:619503
Mowat-Wilson Syndrome Due To Monosomy 2Q22
Motor stereotypy, Impaired pain sensation, Inability to walk, Spasticity, Poor fine motor coordin... ORPHA:261537
Mowat-Wilson Syndrome
Motor stereotypy, Impaired pain sensation, Inability to walk, Ataxia, Spasticity, Broad-based gait ORPHA:2152
Mowat-Wilson Syndrome Due To A Zeb2 Point Mutation
Motor stereotypy, Impaired pain sensation, Inability to walk, Spasticity, Poor fine motor coordin... ORPHA:261552
Deafness, Autosomal Dominant 56
OMIM:615629

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Tnc

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Tnc.

No publications found that use IMPC mice or data for Tnc.

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MGI Allele Allele Type Produced
Tnctm1e(EUCOMM)Wtsi Targeted, non-conditional allele ES Cells
Tnctm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Tnctm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Tnctm2e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells

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