Genes Phenotypes

Gene: Ap1g1

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Name
adaptor protein complex AP-1, gamma 1 subunit
MGI ID
MGI:101919
Synonyms
gamma-adaptin Adtg D8Ertd374e
Viability
Homozygous - Lethal
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (15) Measurements chart (124) All data table (231)
Expression & images (73) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased bone mineral content Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 3.69×10-10
cataract Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 2.33×10-06
abnormal behavioral response to light Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 7.23×10-06
increased lean body mass Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 3.55×10-07
increased bone mineral density Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 5.54×10-05
decreased lean body mass Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 1.56×10-12
abnormal neural tube closure Ap1g1tm1b(EUCOMM)Hmgu HET embryonic day 9.5 0.00
abnormal behavior Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 9.70×10-06
preweaning lethality, complete penetrance Ap1g1tm1b(EUCOMM)Hmgu HOM n/a 0.00
abnormal optic disk morphology Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 8.45×10-05
increased body length Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 2.04×10-06
hyperactivity Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 1.43×10-05
increased total body fat amount Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 2.92×10-05
embryonic growth retardation Ap1g1tm1b(EUCOMM)Hmgu HET embryonic day 9.5 0.00
abnormal retina morphology Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 2.69×10-06

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Section images
Aorta 2 No  (2/2)  Section images
Brain 2 No  (1/2)  Section images
Brainstem 2 No  (1/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/2)  Section images
Cerebellum 2 No  (1/2)  Section images
Cerebral cortex 2 No  (1/2)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (2/2)  Section images
Hippocampus 2 No  (1/2)  Section images
Hypothalamus 2 No  (1/2)  Section images
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584)  (2/2)  Section images
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No  (1/2)  Section images
Olfactory lobe 2 No  (2/2)  Section images
Ovary 2 No  (1/584)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/584)  (1/2)  Section images
Peripheral nervous system 2 No  (1/2)  Section images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2)  Section images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/584)  (2/2)  Section images
Spinal cord 2 No  (1/2)  Section images
Spleen 2 No  (2/584)  (1/2)  Section images
Stomach 2 No  (12/584)  (2/2)  Section images
Striatum 2 No  (1/2)  Section images
Submandibular gland 2 No  (2/132)  (1/2)  Section images
Testis 2 No  (2/584)  (1/2)  Section images
Thalamus 2 No  Section images
Thymus 2 No  (2/2)  Section images
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (1/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
cardiovascular system (3)
Aorta expression
MA:0000062
digestive system (6)
Esophagus expression
MA:0000352
endocrine system (1)
Adrenal gland expression
MA:0000116
exocrine system (1)
Submandibular Gland expression
MA:0001589
immune system (2)
Spleen expression
MA:0000141
integumental system (1)
Skin expression
MA:0000151
nervous system (13)
Brain expression
MA:0000168
postnatal mouse (40)
Adrenal gland expression
MA:0000116
reproductive system (5)
Epididymis expression
MA:0000397
respiratory system (4)
Lung expression
MA:0000415
sensory organ (2)
Eye expression
MA:0000261
set of connective tissues (1)
Cartilage tissue expression
MA:0000104
trunk (22)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Dorsal root ganglion 2  (1/47) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/2)  Wholemount images
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485) N/A
Fronto-nasal process 2  (1/48) N/A
Hand 2  (1/485) N/A
Head 2  (5/485)  (2/2) N/A
Heart 2  (1/485)  (2/2) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Nose 2  (1/51) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Spinal cord 2  (1/50) N/A
Tail 2  (1/485)  (2/2) N/A
Tail somite 2  (1/485) N/A
embryo or Unassigned (8)
Embryo expression
EMAPA:16039 embryo

 Associated Images

X-ray: XRay Images Dorso Ventral
9 Images
X-ray: XRay Images Lateral Orientation
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
Original Image
Adult LacZ: LacZ Images Section
40 Images
X-ray: XRay Images Forepaw
9 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
Embryo LacZ: LacZ images wholemount
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Ap1g1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ap1g1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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