Genes Phenotypes

Gene: Ap1g1

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Name
adaptor protein complex AP-1, gamma 1 subunit
MGI ID
MGI:101919
Synonyms
Adtg gamma-adaptin D8Ertd374e
Viability
Homozygous - Lethal
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (14) Measurements chart (99) All data table (277)
Expression & images (73) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic growth retardation Ap1g1tm1b(EUCOMM)Hmgu HET E9.5 0.00
decreased lean body mass Ap1g1tm1b(EUCOMM)Hmgu HET Early adult 2.54×10-12
abnormal behavior Ap1g1tm1b(EUCOMM)Hmgu HET Early adult 3.27×10-05
increased body length Ap1g1tm1b(EUCOMM)Hmgu HET Early adult 2.98×10-06
hyperactivity Ap1g1tm1b(EUCOMM)Hmgu HET Early adult 3.11×10-05
abnormal optic disk morphology Ap1g1tm1b(EUCOMM)Hmgu HET Early adult 2.08×10-05
preweaning lethality, complete penetrance Ap1g1tm1b(EUCOMM)Hmgu HOM Early adult 0.00
increased total body fat amount Ap1g1tm1b(EUCOMM)Hmgu HET Early adult 2.73×10-05
decreased bone mineral content Ap1g1tm1b(EUCOMM)Hmgu HET Early adult 3.70×10-10
abnormal behavioral response to light Ap1g1tm1b(EUCOMM)Hmgu HET Early adult 2.06×10-05
increased bone mineral density Ap1g1tm1b(EUCOMM)Hmgu HET Early adult 6.27×10-05
abnormal neural tube closure Ap1g1tm1b(EUCOMM)Hmgu HET E9.5 0.00
increased lean body mass Ap1g1tm1b(EUCOMM)Hmgu HET Early adult 5.03×10-07
cataract Ap1g1tm1b(EUCOMM)Hmgu HET Early adult 1.68×10-06

Download data as:  TSV  XLS

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Section images
Aorta 2 No  (2/2)  Section images
Brain 2 No  (1/2)  Section images
Brainstem 2 No  (1/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/2)  Section images
Cerebellum 2 No  (1/2)  Section images
Cerebral cortex 2 No  (1/2)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (2/2)  Section images
Hippocampus 2 No  (1/2)  Section images
Hypothalamus 2 No  (1/2)  Section images
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584)  (2/2)  Section images
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No  (1/2)  Section images
Olfactory lobe 2 No  (2/2)  Section images
Ovary 2 No  (1/584)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/584)  (1/2)  Section images
Peripheral nervous system 2 No  (1/2)  Section images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2)  Section images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/584)  (2/2)  Section images
Spinal cord 2 No  (1/2)  Section images
Spleen 2 No  (2/584)  (1/2)  Section images
Stomach 2 No  (12/584)  (2/2)  Section images
Striatum 2 No  (1/2)  Section images
Submandibular gland 2 No  (2/132)  (1/2)  Section images
Testis 2 No  (2/584)  (1/2)  Section images
Thalamus 2 No  Section images
Thymus 2 No  (2/2)  Section images
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (1/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
cardiovascular system (3)
Aorta expression
MA:0000062
digestive system (6)
Esophagus expression
MA:0000352
endocrine system (1)
Adrenal gland expression
MA:0000116
exocrine system (1)
Submandibular Gland expression
MA:0001589
immune system (2)
Spleen expression
MA:0000141
integumental system (1)
Skin expression
MA:0000151
nervous system (13)
Brain expression
MA:0000168
postnatal mouse (40)
Adrenal gland expression
MA:0000116
reproductive system (5)
Epididymis expression
MA:0000397
respiratory system (4)
Lung expression
MA:0000415
sensory organ (2)
Eye expression
MA:0000261
set of connective tissues (1)
Cartilage tissue expression
MA:0000104
trunk (22)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504) N/A
Dorsal root ganglion 2  (1/57) N/A
Ear 2  (1/504) N/A
Embryo 2  (1/505)  (2/2)  Wholemount images
Eye 2  (1/504) N/A
Foot 2  (1/504) N/A
Forebrain 2  (1/504) N/A
Forelimb 2  (1/504) N/A
Fronto-nasal process 2  (1/58) N/A
Hand 2  (1/503) N/A
Head 2  (5/504)  (2/2) N/A
Heart 2  (1/504)  (2/2) N/A
Hindbrain 2  (6/504) N/A
Hindlimb 2  (1/503) N/A
Liver 2  (1/504) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504) N/A
Maxillary process 2  (1/504) N/A
Midbrain 2  (1/504) N/A
Nose 2  (1/70) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/504) N/A
Spinal cord 2  (1/69) N/A
Tail 2  (1/504)  (2/2) N/A
Tail somite 2  (1/504) N/A
embryo or Unassigned (8)
Embryo expression
EMAPA:16039 embryo

 Associated Images

Original Image
Adult LacZ: LacZ Images Section
40 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Forepaw
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ap1g1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ap1g1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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