Gene: Ap1g1

Name
adaptor protein complex AP-1, gamma 1 subunit
MGI ID
MGI:101919
Synonyms
gamma-adaptin Adtg D8Ertd374e
View
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased lean body mass Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 1.56×10-12
increased body length Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 2.04×10-06
abnormal neural tube closure Ap1g1tm1b(EUCOMM)Hmgu HET embryonic day 9.5 0.00
embryonic growth retardation Ap1g1tm1b(EUCOMM)Hmgu HET embryonic day 9.5 0.00
abnormal behavior Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 9.70×10-06
abnormal optic disk morphology Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 8.45×10-05
preweaning lethality, complete penetrance Ap1g1tm1b(EUCOMM)Hmgu HOM n/a 0.00
decreased bone mineral content Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 3.69×10-10
cataract Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 2.33×10-06
hyperactivity Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 1.43×10-05
increased total body fat amount Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 2.92×10-05
increased lean body mass Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 3.55×10-07
abnormal behavioral response to light Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 7.23×10-06
increased bone mineral density Ap1g1tm1b(EUCOMM)Hmgu HET postnatal 5.54×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Section images
Aorta 2 No  (2/2)  Section images
Brain 2 No  (1/2)  Section images
Brainstem 2 No  (1/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/2)  Section images
Cerebellum 2 No  (1/2)  Section images
Cerebral cortex 2 No  (1/2)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (2/2)  Section images
Hippocampus 2 No  (1/2)  Section images
Hypothalamus 2 No  (1/2)  Section images
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584)  (2/2)  Section images
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No  (1/2)  Section images
Olfactory lobe 2 No  (2/2)  Section images
Ovary 2 No  (1/584)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/584)  (1/2)  Section images
Peripheral nervous system 2 No  (1/2)  Section images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2)  Section images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/584)  (2/2)  Section images
Spinal cord 2 No  (1/2)  Section images
Spleen 2 No  (2/584)  (1/2)  Section images
Stomach 2 No  (12/584)  (2/2)  Section images
Striatum 2 No  (1/2)  Section images
Submandibular gland 2 No  (2/132)  (1/2)  Section images
Testis 2 No  (2/584)  (1/2)  Section images
Thalamus 2 No  Section images
Thymus 2 No  (2/2)  Section images
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (1/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Dorsal root ganglion 2  (1/47) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/2)  Wholemount images
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485) N/A
Fronto-nasal process 2  (1/48) N/A
Hand 2  (1/485) N/A
Head 2  (5/485)  (2/2) N/A
Heart 2  (1/485)  (2/2) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Nose 2  (1/51) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Spinal cord 2  (1/50) N/A
Tail 2  (1/485)  (2/2) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Forepaw
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Lateral Orientation
9 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Dorso Ventral
9 Images
Original Image
Adult LacZ: LacZ Images Section
40 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Ap1g1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ap1g1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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