Gene: Tead1

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Name
TEA domain family member 1
MGI ID
MGI:101876
Synonyms
2610024B07Rik B230114H05Rik TEF-1 Tcf13 TEAD-1 Gtrgeo5 mTEF-1
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased lean body mass Tead1tm1b(KOMP)Wtsi HET Early adult 8.45×10-07
abnormal tooth morphology Tead1tm1b(KOMP)Wtsi HET Early adult 5.27×10-05
preweaning lethality, complete penetrance Tead1tm1a(KOMP)Wtsi HOM Early adult 0.00
abnormal embryo turning Tead1tm1b(KOMP)Wtsi HOM E9.5 0.00
decreased total body fat amount Tead1tm1b(KOMP)Wtsi HET Early adult 2.60×10-09
preweaning lethality, complete penetrance Tead1tm1b(KOMP)Wtsi HOM Early adult 0.00
abnormal embryo size Tead1tm1b(KOMP)Wtsi HOM E9.5 0.00
increased total body fat amount Tead1tm1b(KOMP)Wtsi HET Early adult 2.60×10-09
increased lean body mass Tead1tm1b(KOMP)Wtsi HET Early adult 6.31×10-07
embryonic lethality prior to tooth bud stage Tead1tm1b(KOMP)Wtsi HOM E12.5 0.00
abnormal bone structure Tead1tm1b(KOMP)Wtsi HET Early adult 2.80×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379)  (2/2) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584)  (2/2)  Wholemount images
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (1/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Trigeminal V nerve 2 No  (1/2) N/A
Uterus 2 No  (1/2)  Wholemount images
Vas deferens 2 No  (15/388) N/A
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 3  (1/57)  (3/3) N/A
Axial skeleton 3  (1/61)  (3/3) N/A
Brain 3  (6/504)  (3/3) N/A
Central nervous system ganglion 3  (1/70)  (3/3) N/A
Cranium 3  (1/61)  (3/3) N/A
Dorsal root ganglion 3  (1/57)  (3/3) N/A
Ear 3  (1/504)  (3/3) N/A
Embryo 3  (1/505)  (3/3) N/A
Outer ear 3  (1/66)  (3/3) N/A
Eye 3  (1/504)  (3/3) N/A
Femur pre-cartilage condensation 3  (1/52)  (3/3) N/A
Foot 3  (1/504)  (3/3) N/A
Forearm 3  (1/297)  (3/3) N/A
Forebrain 3  (1/504)  (3/3) N/A
Forelimb 3  (1/504)  (3/3) N/A
Fronto-nasal process 3  (1/58)  (3/3) N/A
Gut 3  (1/56)  (3/3) N/A
Hand 3  (1/503)  (3/3) N/A
Head 3  (5/504)  (3/3) N/A
Head mesenchyme 3  (1/57)  (3/3) N/A
Heart 3  (1/504)  (3/3) N/A
Heart ventricle 3  (1/57)  (3/3) N/A
Hindbrain 3  (6/504)  (3/3) N/A
Hindlimb 3  (1/503)  (3/3) N/A
Humerus pre-cartilage condensation 3  (1/61)  (3/3) N/A
Inner ear 3  (1/61)  (3/3) N/A
Intestine 3  (1/55)  (3/3) N/A
Liver 3  (1/504)  (3/3) N/A
Lower leg 3  (1/297)  (3/3) N/A
Lung 3  (1/500)  (3/3) N/A
Mandibular process 3  (1/504)  (3/3) N/A
Maxillary process 3  (1/504)  (3/3) N/A
Mesonephros of female 3  (1/52)  (3/3) N/A
Mesonephros of male 3  (1/52)  (3/3) N/A
Metanephros 3  (1/52)  (3/3) N/A
Midbrain 3  (1/504)  (3/3) N/A
Nasal septum 3  (1/57)  (3/3) N/A
Nose 3  (1/70)  (3/3) N/A
Notochord 3  (1/57)  (3/3) N/A
Oral cavity 3  (1/504)  (3/3) N/A
Outflow tract 3  (1/57)  (3/3) N/A
Pancreas 3  (1/52)  (3/3) N/A
Pericardium 3  (1/52)  (3/3) N/A
Pharynx 3  (1/52)  (3/3) N/A
Radius-ulna pre-cartilage condensation 3  (1/61)  (3/3) N/A
Rib pre-cartilage condensation 3  (1/54)  (3/3) N/A
Skeleton 3  (1/70)  (3/3) N/A
Skin 3  (1/504)  (3/3) N/A
Spinal cord 3  (1/69)  (3/3) N/A
Stomach 3  (1/52)  (3/3) N/A
Tail 3  (1/504)  (3/3) N/A
Tail somite 3  (1/504)  (3/3) N/A
Thoracic vertebral cartilage condensation 3  (1/52)  (3/3) N/A
Tongue 3  (1/52)  (3/3) N/A
Trachea 3  (1/56)  (3/3) N/A
Trunk mesenchyme 3  (1/57)  (3/3) N/A
Umbilical artery embryonic part 3  (1/57)  (3/3) N/A
Umbilical vein embryonic part 3  (1/57)  (3/3) N/A
Upper arm 3  (1/297)  (3/3) N/A
Upper leg 3  (1/297)  (3/3) N/A
Urinary system 3  (1/56)  (3/3) N/A
Vibrissa 3  (1/66)  (3/3) N/A

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
22 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
22 Images
X-ray: XRay Images Forepaw
22 Images
X-ray: XRay Images Whole Body Lateral Orientation
22 Images
X-ray: XRay Images Whole Body Dorso Ventral
22 Images
Eye Morphology: VIP of left fundus
8 Images
Eye Morphology: VIP of right fundus
14 Images
Eye Morphology: VIP of left eye
2 Images
Eye Morphology: VIP of right eye
1 Images
Adult LacZ: LacZ Images Wholemount
12 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Tead1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells, Tissue
Tead1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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