Gene: Mybl2

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Name
myeloblastosis oncogene-like 2
MGI ID
MGI:101785
Synonyms
Bmyb B-Myb
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Mybl2tm1.1(KOMP)Vlcg HOM   Early adult 0.00
embryonic lethality prior to tooth bud stage Mybl2tm1.1(KOMP)Vlcg HOM   E12.5 0.00
increased neutrophil cell number Mybl2tm1.1(KOMP)Vlcg HET Early adult 4.97×10-06
increased circulating calcium level Mybl2tm1.1(KOMP)Vlcg HET Early adult 2.15×10-05
embryonic lethality prior to organogenesis Mybl2tm1.1(KOMP)Vlcg HOM   E9.5 0.00

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 3 No  (4/583) N/A
Aorta 3 No  (1/583) N/A
Blood 1 No N/A
Bone marrow 1 No N/A
Brain 3 No  (4/583) N/A
Brainstem 3 No  (2/583) N/A
Brown adipose tissue 1 No N/A
Cartilage tissue 3 No  (1/583) N/A
Cecum 1 No  (12/371) N/A
Cerebellum 3 No  (3/583) N/A
Cerebral cortex 3 No  (2/583) N/A
Chest bone 1 No N/A
Colon 1 No  (12/127) N/A
Diaphragm 1 No N/A
Duodenum 1 No  (2/127) N/A
Epididymis 1 No  (18/132)  (1/1)  Section images
Esophagus 3 No  (7/407) N/A
Eye 3 No N/A
Gall bladder 1 No N/A
Gonadal fat pad 1 No N/A
Harderian gland 1 No N/A
Heart 3 No  (2/583) N/A
Hindlimb 1 No N/A
Hippocampus 3 No  (3/583) N/A
Hypothalamus 3 No  (2/583) N/A
Ileum 1 No  (14/127) N/A
Jejunum 1 No  (6/127) N/A
Kidney 3 No  (21/583)  (2/3) N/A
Large intestine 3 No  (10/583)  (2/3) N/A
Liver 3 No  (2/3)  Section images
Lower urinary tract 3 No  (1/583) N/A
Lung 3 No  (2/583) N/A
Lymph node 3 No  (1/583) N/A
Mammary gland 3 No N/A
Mesenteric adipose tissue 1 No N/A
Mesenteric lymph node 1 No N/A
Midbrain 1 No N/A
Olfactory lobe 3 No  (2/583) N/A
Ovary 3 No  (1/583)  (1/3) N/A
Oviduct 3 No  (1/3) N/A
Pancreas 3 No  (5/583)  (2/3)  Section images
Parathyroid gland 1 No  (1/563) N/A
Parotid gland 1 No N/A
Penis 1 No N/A
Peripheral nervous system 3 No  (2/583) N/A
Peyer's patch 3 No N/A
Pituitary gland 3 No  (1/583) N/A
Prostate gland 3 No  (12/583)  (2/3)  Section images
Quadriceps 1 No N/A
Sciatic nerve 1 No N/A
Skeletal muscle 3 No N/A
Skin 3 No  (1/583) N/A
Small intestine 3 No  (9/583)  (2/3) N/A
Spinal cord 3 No  (3/583) N/A
Spleen 3 No  (3/583)  (2/3) N/A
Stomach 3 No  (13/583)  (2/3) N/A
Stomach pyloric region 1 No N/A
Striatum 3 No  (3/583) N/A
Sublingual gland 1 No N/A
Submandibular gland 1 No  (2/130) N/A
Testis 3 No  (6/583)  (2/3)  Section images
Thymus 3 No  (1/583) N/A
Thyroid gland 3 No  (17/583)  (2/3) N/A
Tongue 1 No  (5/127) N/A
Trachea 3 No  (3/583) N/A
Trigeminal V nerve 1 No N/A
Urinary bladder 3 No  (2/3)  Section images
Uterus 3 No  (1/3) N/A
Vagina 1 No N/A
Vas deferens 1 No  (15/382)  (1/1)  Section images
Vascular system 3 No N/A
Vesicular gland 1 No N/A
White adipose tissue 3 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/64) N/A
5  (6/505)  (2/5) N/A
2  (1/73) N/A
5  (1/505) N/A
5  (1/506)  (2/5) N/A
5  (1/505)  (2/5) N/A
5  (1/505) N/A
5  (1/505)  (2/5) N/A
5  (1/505) N/A
2  (1/59) N/A
5  (1/505) N/A
5  (5/505) N/A
5  (1/505)  (2/5) N/A
5  (6/505)  (2/5) N/A
5  (1/505) N/A
5  (1/503) N/A
5  (1/503) N/A
5  (1/505) N/A
5  (1/505) N/A
5  (1/505)  (2/5) N/A
2  (1/75) N/A
5  (1/503) N/A
5  (7/39) N/A
2  (1/75) N/A
5  (1/505) N/A
2  (1/72)  (2/2) N/A
5  (1/505) N/A
5  (1/505) N/A
2  (1/59) N/A
2  (1/59) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Embryo LacZ: LacZ images wholemount
19 Images
Adult LacZ: LacZ Images Section
11 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Mybl2tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Mybl2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Mybl2tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Mybl2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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