A Viability Primary Screen phenotypic assay was performed on a mutant strain carrying the Msh5tm1b(EUCOMM)Wtsi allele. The charts below show the proportion of wild type, heterozygous, and homozygous offspring.
Viability data for Msh5 gene
1 parameter / zygosity / metadata group combinations tested.
| Msh5tm1b(EUCOMM)Wtsi | Viable | homozygote | HMGU | Early adult | H4886-EPD0638_1_B02-1 |
Msh5 Viability Outcome data
Viability OutcomePlease note:
- data for different colonies will be presented separately (e.g. different alleles; same allele but different background strain; same allele but in different phenotyping centers)
- phenotype calls are made when a statistically significant abnormal phenotype is detected (that is, preweaning lethality or absence of expected number of homozygote pups based on Mendelian ratios)
Experiments performed
Associated phenotype
No significant association
Zygosity
homozygote
Testing protocol
Measured value
Viability Outcome
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
HMGU
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Total counts (male and female)
Male counts
Female counts
| Male and female | |||||
| Male | |||||
| Female | N/A |
¹ This Viability procedure (IMPC_VIA_001) does not allow reporting of hemizyous males specifically. This is addressed in the second version (IMPC_VIA_002). Hemizygous males are either reported as homozygous males or the numbers can be derived from the total.