Phenotype: decreased tooth number

Definition
reduction in the number of the bony structures of the upper and lower jaws used in mastication
Synonyms
reduced tooth number,  hypodontia,  reduced number of teeth,  oligodontia,  missing teeth
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased tooth number

Total number of significant genotype-phenotype associations: 4

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Lrrk1
Lrrk1tm1b(KOMP)Wtsi
HOM Early adult absent teeth Combined SHIRPA and Dysmorphology | Teeth presence MRC Harwell | IMPC 9.67×10-10
Lima1
Lima1tm1b(KOMP)Wtsi
HOM Early adult absent teeth Combined SHIRPA and Dysmorphology | Teeth presence JAX | IMPC 2.24×10-05
Zzef1
Zzef1tm2.1(KOMP)Vlcg
HOM Early adult absent teeth Combined SHIRPA and Dysmorphology | Teeth presence JAX | IMPC 3.58×10-05

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 The way we measure

 Phenotype associations stats

0.06% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased tooth number (3/5227)

0.04% females (2/5207) 0.04% males (2/5218)

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