Definition
any structural anomaly of either of the two arches (crescent arrangements) of teeth, one on each jaw, that together constitute the dentition
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with abnormal dental arch morphology
Total number of significant genotype-phenotype associations: 62
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Procedure | Parameter | Phenotyping Center | Source | P Value | |
|---|---|---|---|---|---|---|---|---|
| Mex3b Mex3btm1b(KOMP)Wtsi |
HOM | Early adult | abnormal tooth morphology | Gross Pathology and Tissue Collection | Tooth | CCP-IMG | IMPC | 0.00 | ||
| Mink1 Mink1em1(IMPC)Tcp |
HOM | Early adult | abnormal tooth morphology | Gross Pathology and Tissue Collection | Tooth | TCP | IMPC | 0.00 | ||
| Tent5a Tent5aem1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth morphology | Gross Pathology and Tissue Collection | Tooth | CCP-IMG | IMPC | 0.00 | ||
| Tmem273 Tmem273em1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth morphology | Gross Pathology and Tissue Collection | Tooth | CCP-IMG | IMPC | 0.00 | ||
| Lamb3 Lamb3tm1b(KOMP)Wtsi |
HOM | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Lower teeth appearance | MRC Harwell | IMPC | 1.32×10-21 | ||
| Bnip2 Bnip2tm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal incisor color | Combined SHIRPA and Dysmorphology | Incisor colour | WTSI | IMPC | 3.85×10-17 | ||
| Itga11 Itga11em1(IMPC)H |
HOM | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Upper teeth appearance | MRC Harwell | IMPC | 5.45×10-16 | ||
| Ftl1 Ftl1em1(IMPC)Rbrc |
HOM | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Upper teeth appearance | RBRC | IMPC | 5.02×10-15 | ||
| Lrrk1 Lrrk1tm1b(KOMP)Wtsi |
HOM | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Lower teeth appearance | MRC Harwell | IMPC | 8.59×10-15 | ||
| Ncoa3 Ncoa3tm1b(EUCOMM)Wtsi |
HET | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Lower teeth appearance | MRC Harwell | IMPC | 1.33×10-13 | ||
| Wsb2 Wsb2tm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Upper teeth appearance | HMGU | IMPC | 3.64×10-12 | ||
| Cabp5 Cabp5tm1b(KOMP)Wtsi |
HOM | Middle aged adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Lower teeth appearance | MRC Harwell | IMPC | 6.51×10-12 | ||
| Slc20a2 Slc20a2tm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal incisor color | Combined SHIRPA and Dysmorphology | Incisor colour | WTSI | IMPC | 3.25×10-11 | ||
| Adam23 Adam23tm1b(EUCOMM)Hmgu |
HET | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Lower teeth appearance | MRC Harwell | IMPC | 6.77×10-10 | ||
| Lrrk1 Lrrk1tm1b(KOMP)Wtsi |
HOM | Early adult | absent teeth | Combined SHIRPA and Dysmorphology | Teeth presence | MRC Harwell | IMPC | 9.67×10-10 | ||
| Gfpt2 Gfpt2tm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Upper teeth appearance | HMGU | IMPC | 4.02×10-09 | ||
| Sparc Sparctm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal incisor color | Dysmorphology | Incisor colour | WTSI | EuroPhenome | 5.12×10-09 | ||
| Pdss2 Pdss2tm1b(EUCOMM)Hmgu |
HET | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Lower teeth appearance | MRC Harwell | IMPC | 1.35×10-08 | ||
| Pitx2 Pitx2tm1b(EUCOMM)Wtsi |
HET | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Lower teeth appearance | MRC Harwell | IMPC | 1.35×10-08 | ||
| Pbx3 Pbx3tm1b(EUCOMM)Wtsi |
HET | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Upper teeth appearance | MRC Harwell | IMPC | 8.33×10-08 | ||
| Rgs2 Rgs2em1(IMPC)H |
HOM | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Upper teeth appearance | MRC Harwell | IMPC | 8.33×10-08 | ||
| Tmem189 Tmem189tm1a(KOMP)Wtsi |
HOM | Early adult | abnormal incisor color | Combined SHIRPA and Dysmorphology | Incisor colour | WTSI | IMPC | 2.40×10-07 | ||
| Apoe Apoetm1Unc |
HOM | Early adult | abnormal tooth morphology | X-Ray | Teeth | WTSI | EuroPhenome | 2.51×10-07 | ||
| Atg4b Atg4btm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Lower teeth appearance | MRC Harwell | IMPC | 2.56×10-07 | ||
| Aff3 Aff3tm1a(EUCOMM)Wtsi |
HOM | Early adult | malocclusion | Combined SHIRPA and Dysmorphology | Incisors morphology | WTSI | IMPC | 3.59×10-07 | ||
| Ide Idetm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal incisor morphology | Dysmorphology | Incisor | WTSI | EuroPhenome | 1.73×10-06 | ||
| Ltbp1 Ltbp1tm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal incisor morphology | Dysmorphology | Incisor | WTSI | EuroPhenome | 1.73×10-06 | ||
| Slc25a21 Slc25a21tm1a(KOMP)Wtsi |
HOM | Early adult | abnormal incisor morphology | Dysmorphology | Incisor | WTSI | EuroPhenome | 1.73×10-06 | ||
| Exoc3l2 Exoc3l2tm1a(KOMP)Wtsi |
HOM | Early adult | abnormal tooth morphology | X-ray | Teeth | WTSI | IMPC | 2.05×10-06 | ||
| Aff3 Aff3tm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | X-ray | Teeth | WTSI | IMPC | 2.38×10-06 | ||
| Itch Itchtm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Lower teeth appearance | MRC Harwell | IMPC | 3.70×10-06 | ||
| Setd5 Setd5tm1a(EUCOMM)Wtsi |
HET | Early adult | abnormal tooth morphology | X-ray | Teeth | WTSI | IMPC | 4.08×10-06 | ||
| Cyp2e1 Cyp2e1tm1b(KOMP)Wtsi |
HOM | Early adult | abnormal tooth morphology | X-ray | Teeth | MRC Harwell | IMPC | 4.78×10-06 | ||
| Rlbp1 Rlbp1tm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal tooth morphology | X-ray | Teeth | MRC Harwell | IMPC | 6.36×10-06 | ||
| Exoc3l2 Exoc3l2tm1a(KOMP)Wtsi |
HOM | Early adult | malocclusion | Combined SHIRPA and Dysmorphology | Incisors morphology | WTSI | IMPC | 8.41×10-06 | ||
| Setd5 Setd5tm1a(EUCOMM)Wtsi |
HET | Early adult | malocclusion | Combined SHIRPA and Dysmorphology | Incisors morphology | WTSI | IMPC | 8.41×10-06 | ||
| Hsp90aa1 Hsp90aa1tm1(KOMP)Wtsi |
HOM | Early adult | malocclusion | Combined SHIRPA and Dysmorphology | Incisors morphology | WTSI | IMPC | 1.29×10-05 | ||
| Fam160a2 Fam160a2em1(IMPC)Tcp |
HOM | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Upper teeth appearance | TCP | IMPC | 1.43×10-05 | ||
| Ypel2 Ypel2em1(IMPC)Tcp |
HOM | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Upper teeth appearance | TCP | IMPC | 1.43×10-05 | ||
| Chd1 Chd1tm1b(KOMP)Wtsi |
HET | Early adult | abnormal tooth morphology | X-ray | Teeth | TCP | IMPC | 1.58×10-05 | ||
| Lima1 Lima1tm1b(KOMP)Wtsi |
HOM | Early adult | absent teeth | Combined SHIRPA and Dysmorphology | Teeth presence | JAX | IMPC | 2.24×10-05 | ||
| Fmc1 Fmc1tm1b(EUCOMM)Wtsi |
HET | Early adult | abnormal tooth morphology | X-ray | Teeth | BCM | IMPC | 2.76×10-05 | ||
| Zzef1 Zzef1tm2.1(KOMP)Vlcg |
HOM | Early adult | absent teeth | Combined SHIRPA and Dysmorphology | Teeth presence | JAX | IMPC | 3.58×10-05 | ||
| Tead1 Tead1tm1b(KOMP)Wtsi |
HET | Early adult | abnormal tooth morphology | X-ray | Teeth | BCM | IMPC | 5.27×10-05 | ||
| Zc3hc1 Zc3hc1tm1a(KOMP)Wtsi |
HOM | Early adult | abnormal tooth morphology | X-ray | Teeth | WTSI | MGP | 6.52×10-05 | ||
| Tchp Tchptm1a(EUCOMM)Wtsi |
HOM | Early adult | malocclusion | Combined SHIRPA and Dysmorphology | Incisors morphology | WTSI | IMPC | 6.66×10-05 | ||
| Sdha Sdhatm2b(KOMP)Wtsi |
HET | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Upper teeth appearance | JAX | IMPC | 7.16×10-05 | ||
| Ddc Ddcem1(IMPC)Hmgu |
HET | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Lower teeth appearance | HMGU | IMPC | 7.91×10-05 | ||
| Ppp2r1b Ppp2r1btm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | Combined SHIRPA and Dysmorphology | Lower teeth appearance | MARC | IMPC | 9.14×10-05 | ||
| Agap1 Agap1tm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | X-ray | Teeth | WTSI | IMPC | 9.48×10-05 | ||
| Os9 Os9tm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | X-ray | Teeth | WTSI | IMPC | 9.48×10-05 | ||
| Ropn1l Ropn1ltm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | X-ray | Teeth | WTSI | IMPC | 9.48×10-05 |