Definition
any structural anomaly of either of the two arches (crescent arrangements) of teeth, one on each jaw, that together constitute the dentition
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with abnormal dental arch morphology
Total number of significant genotype-phenotype associations: 129
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Amelx Amelxem1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Amelx Amelxem1(IMPC)Ccpcz |
HEM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Amelx Amelxem1(IMPC)Ccpcz |
HEM | Early adult | abnormal tooth color | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Amelx Amelxem1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth color | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Asphd1 Asphd1em1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Fam122b Fam122bem1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Fam122b Fam122bem1(IMPC)Ccpcz |
HEM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Fam122b Fam122bem1(IMPC)Ccpcz |
HEM | Early adult | abnormal tooth color | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Fam122b Fam122bem1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth color | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Fam219a Fam219aem1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Fbxw16 Fbxw16em1(IMPC)Ccpcz |
HET | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Fbxw18 Fbxw18em1(IMPC)Ccpcz |
HET | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Fbxw20 Fbxw20em1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Krtap9-5 Krtap9-5em1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth color | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Krtap9-5 Krtap9-5em1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Lgr6 Lgr6em1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Lhx5 Lhx5em1(IMPC)Ccpcz |
HET | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Meis3 Meis3tm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal tooth color | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Meis3 Meis3tm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Mex3b Mex3btm1b(KOMP)Wtsi |
HOM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Mink1 Mink1em1(IMPC)Tcp |
HOM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
TCP IMPC |
0.00 | |
| Mmp20 Mmp20em1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Mmp20 Mmp20em1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth color | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Nfam1 Nfam1em1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Odaph Odaphem1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Prdm8 Prdm8em1(IMPC)Wtsi |
HET | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Prss47 Prss47em1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth color | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Prss47 Prss47em1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Tent5a Tent5aem1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Tmem273 Tmem273em1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Zfat Zfatem1(IMPC)Ccpcz |
HET | Early adult | abnormal tooth morphology | Tooth Gross Pathology and Tissue Collection |
CCP-IMG IMPC |
0.00 | |
| Lamb3 Lamb3tm1b(KOMP)Wtsi |
HOM | Early adult | abnormal tooth morphology | Lower teeth appearance Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
6.51×10-22 | |
| Npepps Npeppsem1(IMPC)Hmgu |
HOM | Early adult | abnormal tooth morphology | Upper teeth appearance Combined SHIRPA and Dysmorphology |
HMGU IMPC |
8.16×10-20 | |
| Amelx Amelxem1(IMPC)Ccpcz |
HEM | Early adult | absent teeth | Teeth presence Combined SHIRPA and Dysmorphology |
CCP-IMG IMPC |
5.52×10-19 | |
| Amelx Amelxem1(IMPC)Ccpcz |
HOM | Early adult | absent teeth | Teeth presence Combined SHIRPA and Dysmorphology |
CCP-IMG IMPC |
2.00×10-18 | |
| Camk4 Camk4em1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth morphology | Upper teeth appearance Combined SHIRPA and Dysmorphology |
CCP-IMG IMPC |
2.31×10-18 | |
| Bnip2 Bnip2tm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal incisor color | Incisor colour Combined SHIRPA and Dysmorphology |
WTSI IMPC |
2.23×10-17 | |
| Itga11 Itga11em1(IMPC)H |
HOM | Early adult | abnormal tooth morphology | Upper teeth appearance Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
1.37×10-15 | |
| Ftl1 Ftl1em1(IMPC)Rbrc |
HOM | Early adult | abnormal tooth morphology | Upper teeth appearance Combined SHIRPA and Dysmorphology |
RBRC IMPC |
3.48×10-15 | |
| Lrrk1 Lrrk1tm1b(KOMP)Wtsi |
HOM | Early adult | abnormal tooth morphology | Lower teeth appearance Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
4.99×10-15 | |
| Spred1 Spred1em1(IMPC)Ccpcz |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
CCP-IMG IMPC |
6.14×10-15 | |
| Ncoa3 Ncoa3tm1b(EUCOMM)Wtsi |
HET | Early adult | abnormal tooth morphology | Lower teeth appearance Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
8.35×10-14 | |
| Ftl1 Ftl1em1(IMPC)Rbrc |
HOM | Late adult | abnormal tooth morphology | Upper teeth appearance Combined SHIRPA and Dysmorphology |
RBRC IMPC |
1.06×10-13 | |
| Cabp5 Cabp5tm1b(KOMP)Wtsi |
HOM | Middle aged adult | abnormal tooth morphology | Lower teeth appearance Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
1.39×10-12 | |
| Wsb2 Wsb2tm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal tooth morphology | Upper teeth appearance Combined SHIRPA and Dysmorphology |
HMGU IMPC |
3.49×10-12 | |
| Slc20a2 Slc20a2tm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal incisor color | Incisor colour Combined SHIRPA and Dysmorphology |
WTSI IMPC |
2.26×10-11 | |
| Adam23 Adam23tm1b(EUCOMM)Hmgu |
HET | Early adult | abnormal tooth morphology | Lower teeth appearance Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
4.75×10-10 | |
| Lrrk1 Lrrk1tm1b(KOMP)Wtsi |
HOM | Early adult | absent teeth | Teeth presence Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
7.09×10-10 | |
| Eif3k Eif3kem1(IMPC)Hmgu |
HET | Early adult | abnormal tooth morphology | Upper teeth appearance Combined SHIRPA and Dysmorphology |
HMGU IMPC |
2.20×10-09 | |
| Gfpt2 Gfpt2tm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | Upper teeth appearance Combined SHIRPA and Dysmorphology |
HMGU IMPC |
3.88×10-09 | |
| Sparc Sparctm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal incisor color | Incisor colour Dysmorphology |
WTSI EuroPhenome |
5.12×10-09 | |
| Ltbp1 Ltbp1tm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
WTSI MGP |
5.59×10-09 | |
| Miga2 Miga2tm1a(KOMP)Wtsi |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
WTSI MGP |
8.73×10-09 | |
| Pdss2 Pdss2tm1b(EUCOMM)Hmgu |
HET | Early adult | abnormal tooth morphology | Lower teeth appearance Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
9.91×10-09 | |
| Pitx2 Pitx2tm1b(EUCOMM)Wtsi |
HET | Early adult | abnormal tooth morphology | Lower teeth appearance Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
9.91×10-09 | |
| Slc25a21 Slc25a21tm1a(KOMP)Wtsi |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
WTSI MGP |
3.75×10-08 | |
| Rhobtb3 Rhobtb3tm1a(KOMP)Wtsi |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
WTSI MGP |
1.22×10-07 | |
| Pbx3 Pbx3tm1b(EUCOMM)Wtsi |
HET | Early adult | abnormal tooth morphology | Upper teeth appearance Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
1.65×10-07 | |
| Atg4b Atg4btm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal tooth morphology | Lower teeth appearance Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
1.88×10-07 | |
| Ltbp1 Ltbp1tm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal incisor morphology | Incisor Dysmorphology |
WTSI MGP |
1.97×10-07 | |
| Peds1 Tmem189tm1a(KOMP)Wtsi |
HOM | Early adult | abnormal incisor color | Incisor colour Combined SHIRPA and Dysmorphology |
WTSI IMPC |
2.40×10-07 | |
| Apoe Apoetm1Unc |
HOM | Early adult | abnormal tooth morphology | Teeth X-Ray |
WTSI MGP |
2.51×10-07 | |
| Aff3 Aff3tm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal incisor morphology | Incisors morphology Combined SHIRPA and Dysmorphology |
WTSI IMPC |
2.74×10-07 | |
| Sparc Sparctm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
WTSI EuroPhenome |
4.92×10-07 | |
| Slc6a3 Slc6a3tm1b(KOMP)Wtsi |
HOM | Early adult | absent teeth | Teeth presence Combined SHIRPA and Dysmorphology |
JAX IMPC |
5.59×10-07 | |
| Ide Idetm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal incisor morphology | Incisor Dysmorphology |
WTSI MGP |
9.93×10-07 | |
| Rgs2 Rgs2em1(IMPC)H |
HOM | Early adult | abnormal tooth morphology | Upper teeth appearance Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
1.06×10-06 | |
| Hsd17b4 Hsd17b4em1(IMPC)Tcp |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
TCP IMPC |
1.59×10-06 | |
| Bcorl1 Bcorl1em1(IMPC)Tcp |
HEM | Early adult | abnormal tooth morphology | Teeth X-ray |
TCP IMPC |
1.60×10-06 | |
| Hipk2 Hipk2tm2b(EUCOMM)Hmgu |
HOM | Early adult | abnormal tooth morphology | Upper teeth appearance Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
1.62×10-06 | |
| Slc25a21 Slc25a21tm1a(KOMP)Wtsi |
HOM | Early adult | abnormal incisor morphology | Incisor Dysmorphology |
WTSI MGP |
1.73×10-06 | |
| Exoc3l2 Exoc3l2tm1a(KOMP)Wtsi |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
WTSI IMPC |
1.98×10-06 | |
| Aff3 Aff3tm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
WTSI IMPC |
2.26×10-06 | |
| Bbx Bbxtm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
WTSI EuroPhenome |
2.37×10-06 | |
| Itch Itchtm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal tooth morphology | Lower teeth appearance Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
2.94×10-06 | |
| Slc6a3 Slc6a3tm1b(KOMP)Wtsi |
HOM | Early adult | abnormal tooth morphology | Lower teeth appearance Combined SHIRPA and Dysmorphology |
JAX IMPC |
3.35×10-06 | |
| Sirt1 Sirt1tm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
MRC Harwell IMPC |
3.42×10-06 | |
| Setd5 Setd5tm1a(EUCOMM)Wtsi |
HET | Early adult | abnormal tooth morphology | Teeth X-ray |
WTSI IMPC |
3.90×10-06 | |
| Cyp2e1 Cyp2e1tm1b(KOMP)Wtsi |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
MRC Harwell IMPC |
4.25×10-06 | |
| Rlbp1 Rlbp1tm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
MRC Harwell IMPC |
5.65×10-06 | |
| Fam160a2 Fam160a2em1(IMPC)Tcp |
HOM | Early adult | abnormal tooth morphology | Upper teeth appearance Combined SHIRPA and Dysmorphology |
TCP IMPC |
6.14×10-06 | |
| Ypel2 Ypel2em1(IMPC)Tcp |
HOM | Early adult | abnormal tooth morphology | Upper teeth appearance Combined SHIRPA and Dysmorphology |
TCP IMPC |
6.14×10-06 | |
| Exoc3l2 Exoc3l2tm1a(KOMP)Wtsi |
HOM | Early adult | abnormal incisor morphology | Incisors morphology Combined SHIRPA and Dysmorphology |
WTSI IMPC |
6.43×10-06 | |
| Setd5 Setd5tm1a(EUCOMM)Wtsi |
HET | Early adult | abnormal incisor morphology | Incisors morphology Combined SHIRPA and Dysmorphology |
WTSI IMPC |
6.43×10-06 | |
| Jmjd4 Jmjd4em1(IMPC)Wtsi |
HOM | Early adult | abnormal incisor morphology | Incisors morphology Combined SHIRPA and Dysmorphology |
WTSI IMPC |
8.02×10-06 | |
| Hsp90aa1 Hsp90aa1tm1(KOMP)Wtsi |
HOM | Early adult | abnormal incisor morphology | Incisors morphology Combined SHIRPA and Dysmorphology |
WTSI IMPC |
9.85×10-06 | |
| Chd1 Chd1tm1b(KOMP)Wtsi |
HET | Early adult | abnormal tooth morphology | Teeth X-ray |
TCP IMPC |
1.58×10-05 | |
| Ncoa3 Ncoa3tm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | Lower teeth appearance Combined SHIRPA and Dysmorphology |
MRC Harwell IMPC |
2.90×10-05 | |
| Anks4b Anks4btm2a(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
WTSI MGP |
3.52×10-05 | |
| Ptbp2 Ptbp2em1(IMPC)Hmgu |
HET | Early adult | abnormal tooth morphology | Upper teeth appearance Combined SHIRPA and Dysmorphology |
HMGU IMPC |
3.62×10-05 | |
| Evc2 Evc2em1(IMPC)Mbp |
HOM | Early adult | absent teeth | Teeth presence Combined SHIRPA and Dysmorphology |
UC Davis IMPC |
3.92×10-05 | |
| Gkn1 Gkn1tm1.1(KOMP)Vlcg |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
UC Davis IMPC |
3.97×10-05 | |
| Fmc1 Fmc1tm1b(EUCOMM)Wtsi |
HET | Early adult | abnormal tooth morphology | Teeth X-ray |
BCM IMPC |
4.00×10-05 | |
| Zdhhc20 Zdhhc20em1(IMPC)Hmgu |
HOM | Early adult | abnormal tooth morphology | Lower teeth appearance Combined SHIRPA and Dysmorphology |
HMGU IMPC |
5.15×10-05 | |
| Tchp Tchptm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal incisor morphology | Incisors morphology Combined SHIRPA and Dysmorphology |
WTSI IMPC |
5.55×10-05 | |
| Npepps Npeppsem1(IMPC)Hmgu |
HOM | Early adult | absent teeth | Teeth presence Combined SHIRPA and Dysmorphology |
HMGU IMPC |
5.62×10-05 | |
| Tead1 Tead1tm1b(KOMP)Wtsi |
HET | Early adult | abnormal tooth morphology | Teeth X-ray |
BCM IMPC |
5.81×10-05 | |
| Ddc Ddcem1(IMPC)Hmgu |
HET | Early adult | abnormal tooth morphology | Lower teeth appearance Combined SHIRPA and Dysmorphology |
HMGU IMPC |
7.29×10-05 | |
| Slc38a10 Slc38a10tm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
WTSI MGP |
8.62×10-05 | |
| Agap1 Agap1tm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
WTSI IMPC |
9.12×10-05 | |
| Os9 Os9tm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
WTSI IMPC |
9.12×10-05 | |
| Ropn1l Ropn1ltm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | Teeth X-ray |
WTSI IMPC |
9.12×10-05 | |
| Pvr Pvrem1(IMPC)Wtsi |
HOM | Early adult | abnormal incisor morphology | Incisors morphology Combined SHIRPA and Dysmorphology |
WTSI IMPC |
9.18×10-05 | |
| Ppp2r1b Ppp2r1btm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal tooth morphology | Lower teeth appearance Combined SHIRPA and Dysmorphology |
MARC IMPC |
9.85×10-05 | |
| Sdha Sdhatm2b(KOMP)Wtsi |
HET | Early adult | abnormal tooth morphology | Upper teeth appearance Combined SHIRPA and Dysmorphology |
JAX IMPC |
9.95×10-05 |