IMPC Gene variants with abnormal KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number
Total number of significant genotype-phenotype associations: 7
Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
---|---|---|---|---|---|---|---|
Arhgef1 Arhgef1tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number | KLRG1+ Treg cells - % of Treg Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Arpc1b Arpc1btm1a(EUCOMM)Wtsi |
HOM | Early adult | increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number | KLRG1+ Treg cells - % of Treg Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
Bach2 Bach2tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number | KLRG1+ Treg cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number | KLRG1+ Treg cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Dph6 Dph6tm1a(KOMP)Wtsi |
HOM | Early adult | increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number | KLRG1+ Treg cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
Il27 Il27tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number | KLRG1+ Treg cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number | KLRG1+ Treg cells - % of Treg Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 |