Phenotype: increased cardiac stroke volume

Definition
increase in the volume of blood pushed into the aorta with each beat of the heart
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased cardiac stroke volume

Total number of significant genotype-phenotype associations: 6

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Grem2
Grem2em1(IMPC)Bay
HET Early adult increased cardiac stroke volume Stroke Volume
Echo
BCM
IMPC
1.42×10-09
Gstcd
Gstcdtm1b(EUCOMM)Wtsi
HOM Early adult increased cardiac stroke volume Stroke Volume
Echo
BCM
IMPC
7.94×10-06
Gdf11
Gdf11tm2b(EUCOMM)Hmgu
HET Early adult increased cardiac stroke volume Stroke Volume
Echo
BCM
IMPC
7.99×10-06
Vars2
Vars2em1(IMPC)Bay
HET Early adult increased cardiac stroke volume Stroke Volume
Echo
BCM
IMPC
1.86×10-05
Lep
Leptm1b(EUCOMM)Hmgu
HOM Early adult increased cardiac stroke volume Stroke Volume
Echo
BCM
IMPC
4.92×10-05
AW549877
AW549877tm1b(EUCOMM)Wtsi
HOM Early adult increased cardiac stroke volume Stroke Volume
Echo
BCM
IMPC
5.85×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

0.42% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased cardiac stroke volume (6/1422)

0.21% females (3/1412) 0.27% males (3/1132)



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