IMPC Gene variants with increased cardiac stroke volume
Total number of significant genotype-phenotype associations: 9
Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
---|---|---|---|---|---|---|---|
Hells Hellstm1b(EUCOMM)Wtsi |
HET | Early adult | increased cardiac stroke volume | Stroke Volume Echo |
HMGU IMPC |
3.98×10-11 | |
Psd3 Psd3em1(IMPC)H |
HOM | Late adult | increased cardiac stroke volume | Stroke Volume Echo |
MRC Harwell IMPC |
2.56×10-10 | |
Grem2 Grem2em1(IMPC)Bay |
HET | Early adult | increased cardiac stroke volume | Stroke Volume Echo |
BCM IMPC |
5.19×10-10 | |
Pla2g2e Pla2g2etm1b(EUCOMM)Wtsi |
HOM | Early adult | increased cardiac stroke volume | Stroke Volume Echo |
HMGU IMPC |
2.42×10-06 | |
Lep Leptm1b(EUCOMM)Hmgu |
HOM | Early adult | increased cardiac stroke volume | Stroke Volume Echo |
BCM IMPC |
2.59×10-06 | |
Gdf11 Gdf11tm2b(EUCOMM)Hmgu |
HET | Early adult | increased cardiac stroke volume | Stroke Volume Echo |
BCM IMPC |
3.15×10-06 | |
Fam53b Fam53btm1b(EUCOMM)Hmgu |
HOM | Early adult | increased cardiac stroke volume | Stroke Volume Echo |
HMGU IMPC |
1.27×10-05 | |
Hycc1 Hycc1em1(IMPC)Ccpcz |
HOM | Early adult | increased cardiac stroke volume | Stroke Volume Echo |
CCP-IMG IMPC |
3.06×10-05 | |
Emsy Emsyem1(IMPC)Ccpcz |
HET | Early adult | increased cardiac stroke volume | Stroke Volume Echo |
CCP-IMG IMPC |
9.33×10-05 |