Phenotype: aorta dilation

Definition
the luminal space of the aorta is increased in volume or area, usually with an increase of contained fluid
Synonyms
aortic dilation
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with aorta dilation

Total number of significant genotype-phenotype associations: 10

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Lsm1
Lsm1tm1b(EUCOMM)Hmgu
HET Early adult aorta dilation Echo | Aortic diameter (Dao) HMGU | IMPC 1.69×10-16
1600029I14Rik
1600029I14Riktm1b(KOMP)Wtsi
HOM Early adult aorta dilation Echo | Aortic diameter (Dao) HMGU | IMPC 3.25×10-08
Klrb1
Klrb1tm1b(EUCOMM)Wtsi
HOM Early adult aorta dilation Echo | Aortic diameter (Dao) HMGU | IMPC 1.13×10-06
Nub1
Nub1tm1b(EUCOMM)Hmgu
HOM Early adult aorta dilation Echo | Aortic diameter (Dao) CCP-IMG | IMPC 1.20×10-06
Slc25a15
Slc25a15tm1b(EUCOMM)Hmgu
HET Early adult aorta dilation Echo | Aortic diameter (Dao) HMGU | IMPC 3.25×10-06
Mfn2
Mfn2tm1b(EUCOMM)Wtsi
HET Early adult aorta dilation Echo | Aortic diameter (Dao) HMGU | IMPC 1.31×10-05
Spg20
Spg20tm2b(EUCOMM)Hmgu
HOM Early adult aorta dilation Echo | Aortic diameter (Dao) HMGU | IMPC 2.17×10-05
Bmerb1
Bmerb1em1(IMPC)Ccpcz
HOM Early adult aorta dilation Echo | Aortic diameter (Dao) CCP-IMG | IMPC 2.23×10-05
Pfkfb3
Pfkfb3tm1b(EUCOMM)Wtsi
HET   Early adult aorta dilation Echo | Aortic diameter (Dao) HMGU | IMPC 4.11×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

2.16% of tested genes with null mutations on a B6N genetic background have a phenotype association to aorta dilation (9/417)

0.73% females (3/409) 1.46% males (6/410)



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