Phenotype: aorta dilation

Definition
the luminal space of the aorta is increased in volume or area, usually with an increase of contained fluid
Synonyms
aortic dilation
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with aorta dilation

Total number of significant genotype-phenotype associations: 8

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Lsm1
Lsm1tm1b(EUCOMM)Hmgu
HET Early adult aorta dilation Aortic diameter (Dao)
Echo
HMGU
IMPC
2.29×10-16
Klrb1
Klrb1tm1b(EUCOMM)Wtsi
HOM Early adult aorta dilation Aortic diameter (Dao)
Echo
HMGU
IMPC
1.40×10-08
Nub1
Nub1tm1b(EUCOMM)Hmgu
HOM Early adult aorta dilation Aortic diameter (Dao)
Echo
CCP-IMG
IMPC
9.89×10-07
Spg20
Spg20tm2b(EUCOMM)Hmgu
HOM Early adult aorta dilation Aortic diameter (Dao)
Echo
HMGU
IMPC
1.62×10-06
Asb7
Asb7em1(IMPC)Ccpcz
HOM Early adult aorta dilation Aortic diameter (Dao)
Echo
CCP-IMG
IMPC
6.64×10-06
Bmerb1
Bmerb1em1(IMPC)Ccpcz
HOM Early adult aorta dilation Aortic diameter (Dao)
Echo
CCP-IMG
IMPC
2.82×10-05
Trabd2b
Trabd2bem2(IMPC)Ccpcz
HOM Early adult aorta dilation Aortic diameter (Dao)
Echo
CCP-IMG
IMPC
3.54×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

1.47% of tested genes with null mutations on a B6N genetic background have a phenotype association to aorta dilation (7/475)

0.64% females (3/466) 1.08% males (5/465)



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