Phenotype: aorta dilation

Definition
the luminal space of the aorta is increased in volume or area, usually with an increase of contained fluid
Synonyms
aortic dilation
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with aorta dilation

Total number of significant genotype-phenotype associations: 8

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Lsm1
Lsm1tm1b(EUCOMM)Hmgu
HET Early adult aorta dilation Echo | Aortic diameter (Dao) HMGU | IMPC 2.71×10-16
Klrb1
Klrb1tm1b(EUCOMM)Wtsi
HOM Early adult aorta dilation Echo | Aortic diameter (Dao) HMGU | IMPC 1.72×10-08
Spg20
Spg20tm2b(EUCOMM)Hmgu
HOM Early adult aorta dilation Echo | Aortic diameter (Dao) HMGU | IMPC 1.86×10-06
Nub1
Nub1tm1b(EUCOMM)Hmgu
HOM Early adult aorta dilation Echo | Aortic diameter (Dao) CCP-IMG | IMPC 2.51×10-06
Asb7
Asb7em1(IMPC)Ccpcz
HOM Early adult aorta dilation Echo | Aortic diameter (Dao) CCP-IMG | IMPC 7.26×10-06
Bmerb1
Bmerb1em1(IMPC)Ccpcz
HOM Early adult aorta dilation Echo | Aortic diameter (Dao) CCP-IMG | IMPC 2.66×10-05
Trabd2b
Trabd2bem2(IMPC)Ccpcz
HOM Early adult aorta dilation Echo | Aortic diameter (Dao) CCP-IMG | IMPC 7.98×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

1.64% of tested genes with null mutations on a B6N genetic background have a phenotype association to aorta dilation (7/427)

0.72% females (3/419) 1.19% males (5/420)



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter