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Phenotype: shortened ST segment

Definition
reduction in the length of time between the end of S-wave and the beginning of T-wave; reflects the amount of time the ventricles remain electrically depolarized
Synonyms
reduced ST segment,  decreased ST segment
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with shortened ST segment

Total number of significant genotype-phenotype associations: 14

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Dnajc5b
Dnajc5btm1b(EUCOMM)Hmgu 		HOM Early adult shortened ST segment ST
Electrocardiogram (ECG)		 ICS
IMPC		 5.15×10-09
Pitx3
Pitx3tm1.1(KOMP)Vlcg 		HOM Early adult shortened ST segment ST
Electrocardiogram (ECG)		 JAX
IMPC		 2.38×10-06
Pcdh18
Pcdh18tm1.1(KOMP)Vlcg 		HOM Early adult shortened ST segment ST
Electrocardiogram (ECG)		 UC Davis
IMPC		 2.44×10-06
Ppp2r5c
Ppp2r5cem1(IMPC)Mbp 		HOM Early adult shortened ST segment ST
Electrocardiogram (ECG)		 UC Davis
IMPC		 2.47×10-06
Rrad
Rradtm1.1(KOMP)Vlcg 		HOM   Early adult shortened ST segment ST
Electrocardiogram (ECG)		 JAX
IMPC		 8.99×10-06
Vsig8
Vsig8tm1.1(KOMP)Mbp 		HOM   Early adult shortened ST segment ST
Electrocardiogram (ECG)		 JAX
IMPC		 1.18×10-05
Rnf10
Rnf10tm1b(KOMP)Wtsi 		HOM Early adult shortened ST segment ST
Electrocardiogram (ECG)		 ICS
IMPC		 1.41×10-05
Igfbp3
Igfbp3tm1b(KOMP)Wtsi 		HOM Early adult shortened ST segment ST
Electrocardiogram (ECG)		 MRC Harwell
IMPC		 1.78×10-05
Ebf2
Ebf2em1(IMPC)Mbp 		HET Early adult shortened ST segment ST
Electrocardiogram (ECG)		 UC Davis
IMPC		 2.16×10-05
Gnb2
Gnb2em1(IMPC)J 		HOM   Early adult shortened ST segment ST
Electrocardiogram (ECG)		 JAX
IMPC		 4.55×10-05
Tmem256
Tmem256tm1.1(KOMP)Vlcg 		HOM   Early adult shortened ST segment ST
Electrocardiogram (ECG)		 UC Davis
IMPC		 4.89×10-05
Sorbs2
Sorbs2tm1.1(KOMP)Mbp 		HOM   Early adult shortened ST segment ST
Electrocardiogram (ECG)		 JAX
IMPC		 7.26×10-05
Zfp395
Zfp395tm1b(EUCOMM)Wtsi 		HOM   Early adult shortened ST segment ST
Electrocardiogram (ECG)		 BCM
IMPC		 8.81×10-05
Cldn19
Cldn19tm1.1(KOMP)Vlcg 		HOM   Early adult shortened ST segment ST
Electrocardiogram (ECG)		 JAX
IMPC		 9.56×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Electrocardiogram (ECG)

 Phenotype associations stats

0.32% of tested genes with null mutations on a B6N genetic background have a phenotype association to shortened ST segment (14/4367)

0.05% females (2/4333) 0.12% males (5/4333)



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