Phenotype: shortened ST segment

Definition
reduction in the length of time between the end of S-wave and the beginning of T-wave; reflects the amount of time the ventricles remain electrically depolarized
Synonyms
reduced ST segment,  decreased ST segment
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with shortened ST segment

Total number of significant genotype-phenotype associations: 34

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Gnb2
Gnb2em1(IMPC)J
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST JAX | IMPC 3.07×10-10
Rrad
Rradtm1.1(KOMP)Vlcg
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST JAX | IMPC 7.15×10-09
Pitx3
Pitx3tm1.1(KOMP)Vlcg
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST JAX | IMPC 1.34×10-08
Trip13
Trip13tm1.1(KOMP)Vlcg
HET Early adult shortened ST segment Electrocardiogram (ECG) | ST JAX | IMPC 2.42×10-08
Rundc3a
Rundc3atm1b(EUCOMM)Wtsi
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST BCM | IMPC 2.71×10-08
Dnajc5b
Dnajc5btm1b(EUCOMM)Hmgu
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST ICS | IMPC 5.03×10-08
Dpp10
Dpp10tm1.1(NCOM)Mfgc
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST TCP | IMPC 1.06×10-07
Zfp395
Zfp395tm1b(EUCOMM)Wtsi
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST BCM | IMPC 8.13×10-07
C8a
C8atm1b(EUCOMM)Hmgu
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST TCP | IMPC 1.36×10-06
Loxl1
Loxl1tm1.1(KOMP)Vlcg
HET Early adult shortened ST segment Electrocardiogram (ECG) | ST JAX | IMPC 1.59×10-06
Vsig8
Vsig8tm1.1(KOMP)Mbp
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST JAX | IMPC 1.83×10-06
Trip13
Trip13tm1.1(KOMP)Vlcg
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST JAX | IMPC 5.07×10-06
Cldn13
Cldn13tm1.1(KOMP)Vlcg
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST JAX | IMPC 8.82×10-06
Pacsin2
Pacsin2tm1b(EUCOMM)Hmgu
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST JAX | IMPC 9.06×10-06
Col20a1
Col20a1em1(IMPC)Mbp
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST UC Davis | IMPC 1.02×10-05
Ppp1r9b
Ppp1r9btm1.1(KOMP)Vlcg
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST JAX | IMPC 1.35×10-05
Pja2
Pja2tm1b(EUCOMM)Wtsi
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST BCM | IMPC 1.47×10-05
Rnf10
Rnf10tm1b(KOMP)Wtsi
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST ICS | IMPC 1.92×10-05
Slc8a3
Slc8a3tm1.1(KOMP)Vlcg
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST JAX | IMPC 2.14×10-05
Hnrnpc
Hnrnpctm1b(EUCOMM)Hmgu
HET Early adult shortened ST segment Electrocardiogram (ECG) | ST JAX | IMPC 2.24×10-05
Ebf2
Ebf2em1(IMPC)Mbp
HET Early adult shortened ST segment Electrocardiogram (ECG) | ST UC Davis | IMPC 2.53×10-05
Lin28b
Lin28btm1b(EUCOMM)Hmgu
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST JAX | IMPC 3.11×10-05
Pcdh18
Pcdh18tm1.1(KOMP)Vlcg
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST UC Davis | IMPC 3.49×10-05
Sorbs2
Sorbs2tm1.1(KOMP)Mbp
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST JAX | IMPC 4.15×10-05
Ncald
Ncaldtm1.1(KOMP)Vlcg
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST JAX | IMPC 4.80×10-05
Paqr6
Paqr6tm1b(KOMP)Wtsi
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST BCM | IMPC 5.96×10-05
Tmem256
Tmem256tm1.1(KOMP)Vlcg
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST UC Davis | IMPC 6.19×10-05
Vldlr
Vldlrem1(IMPC)Mbp
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST UC Davis | IMPC 7.90×10-05
Cldn19
Cldn19tm1.1(KOMP)Vlcg
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST JAX | IMPC 8.10×10-05
Igfbp3
Igfbp3tm1b(KOMP)Wtsi
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST MRC Harwell | IMPC 8.17×10-05
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Early adult shortened ST segment Electrocardiogram (ECG) | ST CCP-IMG | IMPC 9.49×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.81% of tested genes with null mutations on a B6N genetic background have a phenotype association to shortened ST segment (30/3705)

0.36% females (13/3649) 0.38% males (14/3647)



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter