Phenotype: shortened PR interval

Definition
decrease in the length of time between the beginning of atrial depolarization and the beginning of ventricular depolarization, measured by the interval from the beginning of the P wave to the beginning of the QRS complex
Synonyms
decreased PR interval,  reduced PR interval
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with shortened PR interval

Total number of significant genotype-phenotype associations: 18

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
MRC Harwell
IMPC
5.28×10-08
Cldn19
Cldn19tm1.1(KOMP)Vlcg
HOM   Early adult shortened PR interval PR
Electrocardiogram (ECG)
JAX
IMPC
4.69×10-07
Sorbs2
Sorbs2tm1.1(KOMP)Mbp
HOM   Early adult shortened PR interval PR
Electrocardiogram (ECG)
JAX
IMPC
1.15×10-06
Eri2
Eri2em1(IMPC)Bay
HET Early adult shortened PR interval PR
Electrocardiogram (ECG)
BCM
IMPC
2.34×10-06
Gnl1
Gnl1em1(IMPC)Tcp
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
TCP
IMPC
8.78×10-06
Limd1
Limd1em1(IMPC)H
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
MRC Harwell
IMPC
9.11×10-06
Gnb2
Gnb2em1(IMPC)J
HOM   Early adult shortened PR interval PR
Electrocardiogram (ECG)
JAX
IMPC
1.39×10-05
Ermp1
Ermp1tm1.1(KOMP)Vlcg
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
JAX
IMPC
1.75×10-05
Zdhhc5
Zdhhc5tm1e.1(EUCOMM)Hmgu
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
HMGU
IMPC
2.80×10-05
Sycp3
Sycp3tm1.1(KOMP)Vlcg
HOM   Early adult shortened PR interval PR
Electrocardiogram (ECG)
JAX
IMPC
3.87×10-05
Efr3b
Efr3bem1(IMPC)Mbp
HOM   Early adult shortened PR interval PR
Electrocardiogram (ECG)
UC Davis
IMPC
4.35×10-05
Iqca
Iqcaem1(IMPC)J
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
JAX
IMPC
4.46×10-05
Cyp4b1
Cyp4b1tm1b(KOMP)Wtsi
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
HMGU
IMPC
4.53×10-05
Gpbp1
Gpbp1tm1b(EUCOMM)Wtsi
HET Early adult shortened PR interval PR
Electrocardiogram (ECG)
HMGU
IMPC
4.99×10-05
Fabp2
Fabp2em1(IMPC)Hmgu
HOM   Early adult shortened PR interval PR
Electrocardiogram (ECG)
HMGU
IMPC
7.14×10-05
Thg1l
Thg1ltm1b(EUCOMM)Wtsi
HET Early adult shortened PR interval PR
Electrocardiogram (ECG)
HMGU
IMPC
9.17×10-05
Gpr150
Gpr150em1(IMPC)J
HOM Early adult shortened PR interval PR
Electrocardiogram (ECG)
JAX
IMPC
9.43×10-05
Ppig
Ppigem1(IMPC)J
HET Early adult shortened PR interval PR
Electrocardiogram (ECG)
JAX
IMPC
9.45×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.35% of tested genes with null mutations on a B6N genetic background have a phenotype association to shortened PR interval (18/5191)

0.12% females (6/5139) 0.12% males (6/5125)



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter