Phenotype: shortened PR interval

Definition
decrease in the length of time between the beginning of atrial depolarization and the beginning of ventricular depolarization, measured by the interval from the beginning of the P wave to the beginning of the QRS complex
Synonyms
decreased PR interval,  reduced PR interval
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with shortened PR interval

Total number of significant genotype-phenotype associations: 26

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Gnl1
Gnl1em1(IMPC)Tcp
HOM Early adult shortened PR interval Electrocardiogram (ECG) | PR TCP | IMPC 1.55×10-10
Dnaaf1
Dnaaf1em1(IMPC)J
HET Early adult shortened PR interval Electrocardiogram (ECG) | PR JAX | IMPC 3.96×10-09
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Early adult shortened PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 2.38×10-08
Gpbp1
Gpbp1tm1b(EUCOMM)Wtsi
HET Early adult shortened PR interval Electrocardiogram (ECG) | PR HMGU | IMPC 6.38×10-07
Gm20498
Gm20498em1(IMPC)J
HOM Early adult shortened PR interval Electrocardiogram (ECG) | PR JAX | IMPC 4.59×10-06
Homer2
Homer2em1(IMPC)J
HOM Early adult shortened PR interval Electrocardiogram (ECG) | PR JAX | IMPC 5.23×10-06
Ypel2
Ypel2em1(IMPC)Tcp
HOM   Early adult shortened PR interval Electrocardiogram (ECG) | PR TCP | IMPC 7.27×10-06
Rab28
Rab28em1(IMPC)J
HOM Early adult shortened PR interval Electrocardiogram (ECG) | PR JAX | IMPC 8.45×10-06
Sorbs2
Sorbs2tm1.1(KOMP)Mbp
HOM   Early adult shortened PR interval Electrocardiogram (ECG) | PR JAX | IMPC 1.18×10-05
Tnks
Tnksem1(IMPC)Hmgu
HOM Early adult shortened PR interval Electrocardiogram (ECG) | PR HMGU | IMPC 1.28×10-05
Ecpas
Ecpasem1(IMPC)J
HOM   Early adult shortened PR interval Electrocardiogram (ECG) | PR JAX | IMPC 1.43×10-05
Pkmyt1
Pkmyt1em1(IMPC)J
HET   Early adult shortened PR interval Electrocardiogram (ECG) | PR JAX | IMPC 2.26×10-05
Scd3
Scd3em1(IMPC)Bay
HOM Early adult shortened PR interval Electrocardiogram (ECG) | PR BCM | IMPC 2.69×10-05
Ythdc2
Ythdc2em1(IMPC)Bay
HOM Early adult shortened PR interval Electrocardiogram (ECG) | PR BCM | IMPC 2.72×10-05
Cav1
Cav1em2(IMPC)Ics
HOM Early adult shortened PR interval Electrocardiogram (ECG) | PR ICS | IMPC 3.23×10-05
A930017K11Rik
A930017K11Riktm1b(KOMP)Wtsi
HOM Early adult shortened PR interval Electrocardiogram (ECG) | PR BCM | IMPC 3.26×10-05
Limd1
Limd1em1(IMPC)H
HOM   Early adult shortened PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 3.26×10-05
AB124611
AB124611tm1.1(KOMP)Vlcg
HOM   Early adult shortened PR interval Electrocardiogram (ECG) | PR UC Davis | IMPC 4.03×10-05
Cyp4b1
Cyp4b1tm1b(KOMP)Wtsi
HOM Early adult shortened PR interval Electrocardiogram (ECG) | PR HMGU | IMPC 4.32×10-05
Ghrhr
Ghrhrtm1.1(KOMP)Vlcg
HOM   Early adult shortened PR interval Electrocardiogram (ECG) | PR JAX | IMPC 4.71×10-05
Kcnv1
Kcnv1em1(IMPC)J
HOM   Early adult shortened PR interval Electrocardiogram (ECG) | PR JAX | IMPC 8.31×10-05
Esrp1
Esrp1em1(IMPC)Mbp
HET Early adult shortened PR interval Electrocardiogram (ECG) | PR UC Davis | IMPC 8.54×10-05
Taf9b
Taf9btm1.1(KOMP)Vlcg
HEM   Early adult shortened PR interval Electrocardiogram (ECG) | PR UC Davis | IMPC 9.39×10-05
Rab31
Rab31em1(IMPC)J
HOM Early adult shortened PR interval Electrocardiogram (ECG) | PR JAX | IMPC 9.48×10-05
Il18bp
Il18bptm1.1(KOMP)Vlcg
HOM   Early adult shortened PR interval Electrocardiogram (ECG) | PR UC Davis | IMPC 9.75×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.52% of tested genes with null mutations on a B6N genetic background have a phenotype association to shortened PR interval (25/4792)

0.23% females (11/4755) 0.11% males (5/4740)



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