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Genes Phenotypes

Phenotype: prolonged RR interval

Definition
increase in the length of the interval between an R wave and the next R wave; the RR interval is the inverse of the heart rate
Synonyms
widened RR interval,  increased RR interval
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with prolonged RR interval

Total number of significant genotype-phenotype associations: 47

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Myo6
Myo6em1(IMPC)Tcp 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR TCP | IMPC 6.27×10-09
Hcn1
Hcn1em1(IMPC)H 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 1.13×10-08
Vgf
Vgfem1(IMPC)H 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 1.27×10-08
Chmp2b
Chmp2bem1(IMPC)Mbp 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 1.69×10-08
Bbox1
Bbox1tm1a(KOMP)Wtsi 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 3.06×10-08
Atp2b3
Atp2b3em1(IMPC)J 		HOM Late adult prolonged RR interval Electrocardiogram (ECG) | RR JAX | IMPC 5.14×10-08
Rab4a
Rab4atm1b(EUCOMM)Hmgu 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 2.13×10-07
Itga11
Itga11em1(IMPC)H 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 4.49×10-07
Pcm1
Pcm1em1(IMPC)Tcp 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR TCP | IMPC 7.85×10-07
Trh
Trhem1(IMPC)Tcp 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR TCP | IMPC 9.06×10-07
Ap4e1
Ap4e1em2(IMPC)Mbp 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 1.14×10-06
Sbno1
Sbno1tm1b(EUCOMM)Hmgu 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 1.42×10-06
Gabra2
Gabra2em1(IMPC)H 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 2.09×10-06
Tmem60
Tmem60em1(IMPC)Ccpcz 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR CCP-IMG | IMPC 2.33×10-06
Mindy2
Mindy2em1(IMPC)H 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 2.38×10-06
Tnfrsf17
Tnfrsf17tm1.1(KOMP)Vlcg 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 2.72×10-06
Tat
Tatem1(IMPC)J 		HOM Late adult prolonged RR interval Electrocardiogram (ECG) | RR JAX | IMPC 2.98×10-06
Grm7
Grm7em1(IMPC)H 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 4.02×10-06
Tnip1
Tnip1tm1b(EUCOMM)Hmgu 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 4.22×10-06
Ndufa6
Ndufa6em1(IMPC)Bay 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR BCM | IMPC 4.43×10-06
Pde2a
Pde2aem1(IMPC)H 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 7.01×10-06
Ccl9
Ccl9tm1.1(KOMP)Vlcg 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 9.18×10-06
Ppm1m
Ppm1mtm2b(EUCOMM)Hmgu 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 1.02×10-05
Got1
Got1tm1b(EUCOMM)Hmgu 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 1.28×10-05
Rest
Resttm2b(EUCOMM)Wtsi 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR HMGU | IMPC 1.30×10-05
Tmem203
Tmem203em1(IMPC)H 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 1.76×10-05
Psme3ip1
Psme3ip1em1(IMPC)Bay 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR BCM | IMPC 2.06×10-05
Lep
Leptm1b(EUCOMM)Hmgu 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR BCM | IMPC 2.11×10-05
Hipk3
Hipk3tm1b(EUCOMM)Hmgu 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR HMGU | IMPC 2.18×10-05
Rbm20
Rbm20em1(IMPC)Mbp 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 2.44×10-05
Rab3gap2
Rab3gap2tm1b(KOMP)Wtsi 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR JAX | IMPC 2.69×10-05
Trim55
Trim55tm2b(EUCOMM)Hmgu 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 3.15×10-05
Ano3
Ano3em2(IMPC)Mbp 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 3.67×10-05
Zbtb37
Zbtb37em1(IMPC)J 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR JAX | IMPC 3.87×10-05
Gcsh
Gcshem1(IMPC)H 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 4.58×10-05
Pak2
Pak2em1(IMPC)H 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 5.15×10-05
Unc45a
Unc45atm1b(EUCOMM)Hmgu 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR HMGU | IMPC 5.25×10-05
Col9a3
Col9a3em1(IMPC)Tcp 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR TCP | IMPC 5.34×10-05
Stx6
Stx6em1(IMPC)H 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 7.33×10-05
Prkra
Prkraem1(IMPC)H 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 8.26×10-05
Ubap2l
Ubap2lem1(IMPC)Bay 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR BCM | IMPC 8.83×10-05
Masp1
Masp1tm1.1(KOMP)Vlcg 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR JAX | IMPC 9.68×10-05
P3h2
P3h2em1(IMPC)H 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 0.000100

Download data as:   TSV   XLS

 The way we measure

Procedure
Electrocardiogram (ECG)

 Phenotype associations stats

0.98% of tested genes with null mutations on a B6N genetic background have a phenotype association to prolonged RR interval (43/4397)

0.30% females (13/4351) 0.55% males (24/4341)

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