Phenotype: prolonged RR interval

Definition increase in the length of the interval between an R wave and the next R wave; the RR interval is the inverse of the heart rate

Synonyms
  • increased RR interval
  • increased RR interval
  • widened RR interval
  • widened RR interval

MP browserMP:0010506

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Phenotype associations stats

0.33% of tested genes with null mutations on a B6N genetic background have a phenotype association to prolonged RR interval (8/2455)

0.24% females (6/2451) 0.20% males (5/2451)



Gene variants with prolonged RR interval

Total number of significant genotype-phenotype associations: 11

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Uhrf2
Uhrf2tm1b(EUCOMM)Wtsi
HOM Female postnatal prolonged RR interval Electrocardiogram (ECG) | RR TCP | IMPC 2.29E-8
Rab3gap2
Rab3gap2tm1b(KOMP)Wtsi
HOM Female Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR JAX | IMPC 2.18E-7
Bbox1
Bbox1tm1a(KOMP)Wtsi
HOM Female Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 2.85E-7
Tnfrsf17
Tnfrsf17tm1.1(KOMP)Vlcg
HOM Female postnatal prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 6.12E-7
P3h1
P3h1tm1b(EUCOMM)Wtsi
HOM Female postnatal prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 7.41E-6
Ccr6
Ccr6tm1.1(KOMP)Vlcg
HOM Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 9.62E-6
Gpr108
Gpr108tm1b(EUCOMM)Hmgu
HOM Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR ICS | IMPC 6.15E-5
Trh
Trhem1Tcp
HOM Female Male postnatal prolonged RR interval Electrocardiogram (ECG) | RR TCP | IMPC 6.87E-5

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