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Phenotype: prolonged RR interval

Definition
increase in the length of the interval between an R wave and the next R wave; the RR interval is the inverse of the heart rate
Synonyms
widened RR interval,  increased RR interval
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with prolonged RR interval

Total number of significant genotype-phenotype associations: 46

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Creg2
Creg2em1(IMPC)J 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR JAX | IMPC 1.68×10-09
Atp2b3
Atp2b3em1(IMPC)J 		HOM   Late adult prolonged RR interval Electrocardiogram (ECG) | RR JAX | IMPC 5.14×10-08
Hcn1
Hcn1em1(IMPC)H 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 6.34×10-08
Zfp280d
Zfp280dem1(IMPC)Hmgu 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR HMGU | IMPC 1.29×10-07
Bbox1
Bbox1tm1a(KOMP)Wtsi 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 1.61×10-07
Ablim3
Ablim3em1(IMPC)Tcp 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR TCP | IMPC 1.77×10-07
Ap4e1
Ap4e1em2(IMPC)Mbp 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 6.49×10-07
Rab4a
Rab4atm1b(EUCOMM)Hmgu 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 6.56×10-07
Trh
Trhem1(IMPC)Tcp 		HOM   Early adult prolonged RR interval Electrocardiogram (ECG) | RR TCP | IMPC 1.26×10-06
Mindy2
Mindy2em1(IMPC)H 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 1.42×10-06
Eftud2
Eftud2tm1b(KOMP)Wtsi 		HET Late adult prolonged RR interval Electrocardiogram (ECG) | RR ICS | IMPC 1.61×10-06
Ist1
Ist1em1(IMPC)J 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR JAX | IMPC 2.48×10-06
Ano3
Ano3em2(IMPC)Mbp 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 3.57×10-06
Ndufa6
Ndufa6em1(IMPC)Bay 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR BCM | IMPC 3.64×10-06
Six1
Six1em1(IMPC)Mbp 		HET Late adult prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 4.72×10-06
Tat
Tatem1(IMPC)J 		HOM Late adult prolonged RR interval Electrocardiogram (ECG) | RR JAX | IMPC 4.72×10-06
Tmem60
Tmem60em1(IMPC)Ccpcz 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR CCP-IMG | IMPC 5.18×10-06
Pycrl
Pycrlem1(IMPC)J 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR JAX | IMPC 5.72×10-06
Pde2a
Pde2aem1(IMPC)H 		HET   Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 6.25×10-06
Sbno1
Sbno1tm1b(EUCOMM)Hmgu 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 8.46×10-06
Ccl9
Ccl9tm1.1(KOMP)Vlcg 		HOM   Early adult prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 9.18×10-06
Cisd1
Cisd1em1(IMPC)Hmgu 		HOM   Early adult prolonged RR interval Electrocardiogram (ECG) | RR HMGU | IMPC 1.31×10-05
Rest
Resttm2b(EUCOMM)Wtsi 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR HMGU | IMPC 1.33×10-05
Atp7a
Atp7aem1(IMPC)J 		HOM   Late adult prolonged RR interval Electrocardiogram (ECG) | RR JAX | IMPC 1.34×10-05
Try10
Try10em1(IMPC)J 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR JAX | IMPC 1.63×10-05
Lep
Leptm1b(EUCOMM)Hmgu 		HOM   Early adult prolonged RR interval Electrocardiogram (ECG) | RR BCM | IMPC 2.12×10-05
Rbm20
Rbm20em1(IMPC)Mbp 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 2.13×10-05
Hipk3
Hipk3tm1b(EUCOMM)Hmgu 		HOM   Early adult prolonged RR interval Electrocardiogram (ECG) | RR HMGU | IMPC 2.18×10-05
Psme3ip1
Psme3ip1em1(IMPC)Bay 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR BCM | IMPC 2.20×10-05
Trim55
Trim55tm2b(EUCOMM)Hmgu 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 2.25×10-05
Gabra2
Gabra2em1(IMPC)H 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 2.82×10-05
Vgf
Vgfem1(IMPC)H 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 2.92×10-05
Unc45a
Unc45atm1b(EUCOMM)Hmgu 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR HMGU | IMPC 2.99×10-05
Pcm1
Pcm1em1(IMPC)Tcp 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR TCP | IMPC 3.69×10-05
Rab3gap2
Rab3gap2tm1b(KOMP)Wtsi 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR JAX | IMPC 3.74×10-05
Klk4
Klk4tm1.1(KOMP)Vlcg 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 3.82×10-05
Myo6
Myo6em1(IMPC)Tcp 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR TCP | IMPC 4.08×10-05
Tmem203
Tmem203em1(IMPC)H 		HOM   Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 5.28×10-05
Chmp2b
Chmp2bem1(IMPC)Mbp 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 7.40×10-05
Zfp593
Zfp593em1(IMPC)J 		HOM Early adult prolonged RR interval Electrocardiogram (ECG) | RR JAX | IMPC 7.53×10-05
Pak2
Pak2em1(IMPC)H 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 8.04×10-05
Ubap2l
Ubap2lem1(IMPC)Bay 		HET   Early adult prolonged RR interval Electrocardiogram (ECG) | RR BCM | IMPC 8.14×10-05
Dyrk1b
Dyrk1btm1b(EUCOMM)Wtsi 		HET Late adult prolonged RR interval Electrocardiogram (ECG) | RR ICS | IMPC 8.29×10-05
P3h2
P3h2em1(IMPC)H 		HET Early adult prolonged RR interval Electrocardiogram (ECG) | RR MRC Harwell | IMPC 9.36×10-05
Maged1
Maged1em1(IMPC)Mbp 		HEM   Early adult prolonged RR interval Electrocardiogram (ECG) | RR UC Davis | IMPC 9.72×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Electrocardiogram (ECG)

 Phenotype associations stats

0.94% of tested genes with null mutations on a B6N genetic background have a phenotype association to prolonged RR interval (45/4792)

0.29% females (14/4755) 0.44% males (21/4741)

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